2024
A simple, field-applicable method to increase the infectivity of wild isolates of Plasmodium falciparum to mosquito vectors
Ouattara S, Hien D, Nao E, Paré P, Guissou E, Cohuet A, Morlais I, Yerbanga R, Dabiré K, Ouédraogo J, Mouline K, Lefèvre T. A simple, field-applicable method to increase the infectivity of wild isolates of Plasmodium falciparum to mosquito vectors. Malaria Journal 2024, 23: 135. PMID: 38711028, PMCID: PMC11075210, DOI: 10.1186/s12936-024-04969-0.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnophelesFeeding BehaviorFemaleHumansMalaria, FalciparumMosquito VectorsPlasmodium falciparumConceptsDirect membrane feeding assaysGametocyte densityHuman-to-mosquito transmissionDonor bloodLow gametocyte densitiesMembrane feeding assaysPlasmodium falciparum gametocytesTransmission-blocking interventionsWhole bloodInfection rateFalciparum gametocytesInfectious reservoirNaive serumAsymptomatic individualsMosquito infectionHuman donorsRemoval of plasmaEndemic countriesSerumPlasmodiumParasite isolatesInfectionBlood treatmentGametocytesPlasma volume
2022
Evaluation of the Pfs25-IMX313/Matrix-M malaria transmission-blocking candidate vaccine in endemic settings
Mulamba C, Williams C, Kreppel K, Ouedraogo J, Olotu A. Evaluation of the Pfs25-IMX313/Matrix-M malaria transmission-blocking candidate vaccine in endemic settings. Malaria Journal 2022, 21: 159. PMID: 35655174, PMCID: PMC9161629, DOI: 10.1186/s12936-022-04173-y.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsHumansInsecticide ResistanceMalaria VaccinesMosquito VectorsNanoparticlesSaponinsConceptsEndemic settingsMalaria transmission-blocking vaccineHuman vaccine trialsTransmission-blocking vaccinesPublic health importanceMosquito vectorsMiddle-income settingsAnti-malarial drugsImmunological mechanismsCandidate vaccinesVaccine trialsHealthy individualsIncome settingsTransmission blockingHealth importanceMalaria controlMalaria parasitesVaccineLocal interventionsDrugsInterventionSettingSexual stagesPfs25Disease
2021
Contrasting effects of the alkaloid ricinine on the capacity of Anopheles gambiae and Anopheles coluzzii to transmit Plasmodium falciparum
Hien D, Paré P, Cooper A, Koama B, Guissou E, Yaméogo K, Yerbanga R, Farrell I, Ouédraogo J, Gnankiné O, Ignell R, Cohuet A, Dabiré R, Stevenson P, Lefèvre T. Contrasting effects of the alkaloid ricinine on the capacity of Anopheles gambiae and Anopheles coluzzii to transmit Plasmodium falciparum. Parasites & Vectors 2021, 14: 479. PMID: 34526119, PMCID: PMC8444468, DOI: 10.1186/s13071-021-04992-z.Peer-Reviewed Original ResearchConceptsAnopheles coluzziiAnopheles gambiaeCastor bean Ricinus communisSecondary phytochemicalsKey phenotypic traitsNovel control agentsPlant-derived sugarsAbility of mosquitoesPhenotypic traitsPlasmodium falciparumParasite growth ratePlant sugarsPlant nectarFeeding assaysControl agentsMosquito physiologyGrowth rateAnopheles speciesSensu latoAnopheles gambiae sensu latoColuzziiGambiae sensu latoPutative roleP. falciparum infectionMosquito survivalInsecticide resistance profiles in malaria vector populations from Sud-Kivu in the Democratic Republic of the Congo
N'Do S, Bandibabone J, Soma D, Musaka B, Prudhomme J, Habamungu C, Namountougou M, Sangaré I, Kientega M, Kaboré D, Bayili K, Yerbanga R, Diabate A, Dabire R, Ouedraogo J, Belem A, Boëte C, Guardiola-Claramonte M, Chimanuka B. Insecticide resistance profiles in malaria vector populations from Sud-Kivu in the Democratic Republic of the Congo. Transactions Of The Royal Society Of Tropical Medicine And Hygiene 2021, 115: 1339-1344. PMID: 34324683, DOI: 10.1093/trstmh/trab116.Peer-Reviewed Original ResearchConceptsA. gambiaeInsecticide resistance profileInsecticide resistanceAce-1R mutationMalaria vector populationsVector populationsInsecticide susceptibility bioassaysWild populationsAce-1RPiperonyl butoxideAnopheles gambiaeKdr mutationSusceptibility bioassaysSusceptibility of vectorsMosquito speciesGambiaeAnopheles funestusVector susceptibilitySud-KivuMutationsA. funestusVector control toolsResistance status
2020
High Plasmodium infection intensity in naturally infected malaria vectors in Africa
Bompard A, Da D, Yerbanga S, Morlais I, Awono-Ambéné P, Dabiré R, Ouédraogo J, Lefèvre T, Churcher T, Cohuet A. High Plasmodium infection intensity in naturally infected malaria vectors in Africa. International Journal For Parasitology 2020, 50: 985-996. PMID: 32681932, DOI: 10.1016/j.ijpara.2020.05.012.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnophelesBurkina FasoCross-Sectional StudiesHumansMalariaMosquito VectorsOocystsPlasmodium falciparumConceptsOocyst-positive mosquitoesInfectious blood mealEfficacy of transmissionControl of malariaWild malaria vectorsMalaria parasite transmissionCross-sectional surveyInfection loadSalivary gland sporozoitesMalaria vectorsMalaria endemicityNumber of oocystsInfected mosquitoesMalaria transmissionOocyst prevalenceStrong positive associationPrevalencePositive associationBlood mealOocyst loadInfection intensityEpidemiologyEfficacyParasite transmissionInterventionDifferent distribution of malaria parasite in left and right extremities of vertebrate hosts translates into differences in parasite transmission
Pigeault R, Isaïa J, Yerbanga R, Dabiré K, Ouédraogo J, Cohuet A, Lefèvre T, Christe P. Different distribution of malaria parasite in left and right extremities of vertebrate hosts translates into differences in parasite transmission. Scientific Reports 2020, 10: 10183. PMID: 32576924, PMCID: PMC7311528, DOI: 10.1038/s41598-020-67180-6.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCanariesCarrier StateChildChild, PreschoolCulexFemaleHumansMalaria, FalciparumMaleMosquito VectorsPlasmodiumVertebratesConceptsGametocyte densityMosquito infection ratesBlood samplesInfection rateNew malaria control strategiesMajor global causeMalaria control strategiesLow parasite burdenGametocyte burdenGametocyte carriersParasite transmissionPlasmodium infectionMosquito transmission potentialRight extremitiesTransmissible stagesParasite burdenMosquito transmissionMalaria parasitesPlasmodium sppGlobal causeTransmission potentialGametocytesVector-borne diseasesDiseaseExtremities