2023
The impact of anti-malarial markets on artemisinin resistance: perspectives from Burkina Faso
Guissou R, Amaratunga C, de Haan F, Tou F, Cheah P, Yerbanga R, Moors E, Dhorda M, Tindana P, Boon W, Dondorp A, Ouédraogo J. The impact of anti-malarial markets on artemisinin resistance: perspectives from Burkina Faso. Malaria Journal 2023, 22: 269. PMID: 37705004, PMCID: PMC10498571, DOI: 10.1186/s12936-023-04705-0.Peer-Reviewed Original ResearchConceptsDepth interviewsGroup discussionsNational policy makersDrug marketBurkina FasoFocus group discussionsPolicy publicationsPublic policyCommunity membersFunding systemPolicy makersAfrican countriesPolicyAnti-malarial policyMarket characteristicsAnti-malarial marketInterviewsRepresentative sampleGrey literatureMarketFasoPerspectiveEmergenceTerms of availabilityDiscussion
2015
Dynamic of plasmodium falciparum chloroquine resistance transporter gene Pfcrt K76T mutation five years after withdrawal of chloroquine in Burkina Faso
Sondo P, Derra K, Tarnagda Z, Nakanabo S, Zampa O, Kazienga A, Valea I, Sorgho H, Ouedraogo J, Guiguemde T, Tinto H. Dynamic of plasmodium falciparum chloroquine resistance transporter gene Pfcrt K76T mutation five years after withdrawal of chloroquine in Burkina Faso. Pan African Medical Journal 2015, 21: 101. PMID: 26516402, PMCID: PMC4606025, DOI: 10.11604/pamj.2015.21.101.6437.Peer-Reviewed Original Research
2014
Polymorphisms in Plasmodium falciparum Chloroquine Resistance Transporter and Multidrug Resistance 1 Genes: Parasite Risk Factors That Affect Treatment Outcomes for P. falciparum Malaria After Artemether-Lumefantrine and Artesunate-Amodiaquine
Venkatesan M, Gadalla N, Stepniewska K, Dahal P, Nsanzabana C, Moriera C, Price R, Mårtensson A, Rosenthal P, Dorsey G, Sutherland C, Guérin P, Davis T, Ménard D, Adam I, Ademowo G, Arze C, Baliraine F, Berens-Riha N, Björkman A, Borrmann S, Checchi F, Desai M, Dhorda M, Djimdé A, El-Sayed B, Eshetu T, Eyase F, Falade C, Faucher J, Fröberg G, Grivoyannis A, Hamour S, Houzé S, Johnson J, Kamugisha E, Kariuki S, Kiechel J, Kironde F, Kofoed P, LeBras J, Malmberg M, Mwai L, Ngasala B, Nosten F, Nsobya S, Nzila A, Oguike M, Otienoburu S, Ogutu B, Ouédraogo J, Piola P, Rombo L, Schramm B, Somé A, Thwing J, Ursing J, Wong R, Zeynudin A, Zongo I, Plowe C, Sibley C, Asaq Molecular Marker Study Group. Polymorphisms in Plasmodium falciparum Chloroquine Resistance Transporter and Multidrug Resistance 1 Genes: Parasite Risk Factors That Affect Treatment Outcomes for P. falciparum Malaria After Artemether-Lumefantrine and Artesunate-Amodiaquine. American Journal Of Tropical Medicine And Hygiene 2014, 91: 833-843. PMID: 25048375, PMCID: PMC4183414, DOI: 10.4269/ajtmh.14-0031.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SubstitutionAmodiaquineAntimalarialsArtemetherArtemisininsChildChild, PreschoolChloroquineDatasets as TopicDrug CombinationsDrug ResistanceDrug Therapy, CombinationEthanolaminesFluorenesGenetic MarkersGenotypeHumansInfantKaplan-Meier EstimateLumefantrineMalaria, FalciparumMembrane Transport ProteinsMultidrug Resistance-Associated ProteinsPlasmodium falciparumPolymorphism, GeneticProtozoan ProteinsRisk FactorsConceptsArtemether-lumefantrineP. falciparum multidrug resistance 1 genePlasmodium falciparum chloroquine resistance transporterPfmdr1 copy numberArtemisinin combination therapyIndividual patient dataChloroquine resistance transporterMultidrug resistance 1 geneWorldWide Antimalarial Resistance NetworkParasitologic cureCombination therapyParasite polymorphismsPartner drugsTherapeutic responseClinical trialsRelevant outcomesArtemisinin componentPatient dataResistance transporterStandardized methodPolymorphismPatientsPfmdr1PfcrtAmodiaquine
2008
Chloroquine‐resistance molecular markers (Pfcrt T76 and Pfmdr‐1 Y86) and amodiaquine resistance in Burkina Faso
Tinto H, Guekoun L, Zongo I, Guiguemdé R, D’Alessandro U, Ouédraogo J. Chloroquine‐resistance molecular markers (Pfcrt T76 and Pfmdr‐1 Y86) and amodiaquine resistance in Burkina Faso. Tropical Medicine And International Health 2008, 13: 238-240. PMID: 18304270, DOI: 10.1111/j.1365-3156.2007.01995.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAmodiaquineAnimalsAntimalarialsBurkina FasoChildChild, PreschoolChloroquineDrug ResistanceHumansInfantInfant, NewbornMalaria, FalciparumMembrane Transport ProteinsMultidrug Resistance-Associated ProteinsMutationPlasmodium falciparumPolymerase Chain ReactionPrevalenceProtozoan ProteinsTreatment FailureTreatment Outcome
2007
Sulfadoxine-pyrimethamine efficacy and selection of Plasmodium falciparum DHFR mutations in Burkina Faso before its introduction as intermittent preventive treatment for pregnant women.
Tinto H, Ouédraogo J, Zongo I, van Overmeir C, van Marck E, Guiguemdé T, D'Alessandro U. Sulfadoxine-pyrimethamine efficacy and selection of Plasmodium falciparum DHFR mutations in Burkina Faso before its introduction as intermittent preventive treatment for pregnant women. American Journal Of Tropical Medicine And Hygiene 2007, 76: 608-13. PMID: 17426157, DOI: 10.4269/ajtmh.2007.76.608.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnimalsAntimalarialsBurkina FasoChildChild, PreschoolChloroquineDrug Administration ScheduleDrug CombinationsDrug ResistanceFemaleGenotypeHumansInfantMalaria, FalciparumMaleMutationPlasmodium falciparumPregnancyPregnancy Complications, ParasiticPyrimethamineSelection, GeneticSulfadoxineTetrahydrofolate DehydrogenaseConceptsSulfadoxine-pyrimethamine efficacyTriple dhfr mutationDHFR mutationsRecurrent parasitemiaIntermittent preventive treatmentSulfadoxine-pyrimethamine resistanceYears of ageSuch high prevalenceDihydropteroate synthetase (Pfdhps) mutationsPCR-restriction fragment length polymorphismSulfadoxine-pyrimethamineTreatment failurePregnant womenPolymerase chain reactionPreventive treatmentHigh prevalenceNew infectionsChain reactionMutant parasitesPatientsParasitemiaTreatmentFragment length polymorphismPrevalenceEfficacy
2006
In vivo sensitivity of Plasmodium faciparum to chloroquine and sulfadoxine pyrimethamine in the Bobo Dioulasso region (1998-2001): risk factors associated with treatments failures to the two drugs.
Tinto H, Sanou B, Erhart A, D'Alessandro U, Ouédraogo J, Guiguemdé T. In vivo sensitivity of Plasmodium faciparum to chloroquine and sulfadoxine pyrimethamine in the Bobo Dioulasso region (1998-2001): risk factors associated with treatments failures to the two drugs. Bulletin De La Société De Pathologie Exotique 2006, 99: 161-5. PMID: 16983817.Peer-Reviewed Original ResearchConceptsCQ treatment failureTreatment failureRisk factorsMultivariate analysisVivo field testTotal treatment failureYears of ageTime of recruitmentSignificant increaseSulfadoxine-pyrimethamineCQ groupUnivariate analysisHealth centersAge of childrenLate failureLow parasitaemiaBetter efficacyDay 14Therapeutic efficacyDay 0SP groupVivo sensitivityParasitaemiaChloroquineDrugs
2005
Usefulness of the Plasmodium falciparum chloroquine resistance transporter T76 genotype failure index for the estimation of in vivo chloroquine resistance in Burkina Faso.
Tinto H, Sanou B, Dujardin J, Ouédraogo J, VAN Overmeir C, Erhart A, VAN Marck E, Guiguemdé T, D'Alessandro U. Usefulness of the Plasmodium falciparum chloroquine resistance transporter T76 genotype failure index for the estimation of in vivo chloroquine resistance in Burkina Faso. American Journal Of Tropical Medicine And Hygiene 2005, 73: 171-3. PMID: 16014853, DOI: 10.4269/ajtmh.2005.73.171.Peer-Reviewed Original Research
2003
Relationship between the Pfcrt T76 and the Pfmdr-1 Y86 mutations in Plasmodium falciparum and in vitro/in vivo chloroquine resistance in Burkina Faso, West Africa
Tinto H, Ouédraogo J, Erhart A, Van Overmeir C, Dujardin J, Van Marck E, Guiguemdé T, D’Alessandro U. Relationship between the Pfcrt T76 and the Pfmdr-1 Y86 mutations in Plasmodium falciparum and in vitro/in vivo chloroquine resistance in Burkina Faso, West Africa. Infection Genetics And Evolution 2003, 3: 287-292. PMID: 14636690, DOI: 10.1016/j.meegid.2003.08.002.Peer-Reviewed Original ResearchConceptsPfcrt T76 mutationT76 mutationPfcrt T76CQ resistancePlasmodium falciparumVivo chloroquine resistancePre-treatment samplesPfcrt K76Uncomplicated malariaChloroquine resistanceStrong linkage disequilibriumGeometric mean valuesBurkina FasoSuch associationsChloroquinePrevious reportsFalciparumMutationsT76
2002
Chloroquine and sulphadoxine‐pyrimethamine efficacy for uncomplicated malaria treatment and haematological recovery in children in Bobo‐Dioulasso, Burkina Faso during a 3‐year period 1998–2000
Tinto H, Zoungrana E, Coulibaly S, Ouedraogo J, Traoré M, Guiguemde T, Van Marck E, D'Alessandro U. Chloroquine and sulphadoxine‐pyrimethamine efficacy for uncomplicated malaria treatment and haematological recovery in children in Bobo‐Dioulasso, Burkina Faso during a 3‐year period 1998–2000. Tropical Medicine And International Health 2002, 7: 925-930. PMID: 12390597, DOI: 10.1046/j.1365-3156.2002.00952.x.Peer-Reviewed Original ResearchConceptsPrevalence of anemiaClinical failureParasitological resistancePacked cell volumeUncomplicated malariaDay 14Day 0Uncomplicated malaria treatmentHaematological recoveryMalaria treatmentCQ resistanceHealth centersRegular surveillanceAntimalarial drugsChloroquineBurkina FasoPrevalenceBobo-DioulassoChildrenAnemiaEvidence of increasesMalariaTreatmentFailureCell volume
2000
The simplified isotopic microtest: a method for studying the drug resistance in vitro of Plasmodium falciparum to antimalarial drugs.
Tinto H, Ouédraogo J, Coulibaly S, Traoré B, Guiguemdé T. The simplified isotopic microtest: a method for studying the drug resistance in vitro of Plasmodium falciparum to antimalarial drugs. Cahiers De Santé 2000, 10: 353-6. PMID: 11125342.Peer-Reviewed Original Research
1998
In vitro sensitivity of Plasmodium falciparum to halofantrine compared with chloroquine, quinine and mefloquine in the region of Bobo-Dioulasso, Burkina Faso (West Africa).
Ouédraogo J, Dutheil Y, Tinto H, Traoré B, Zampa H, Tall F, Coulibaly S, Guiguemdé T. In vitro sensitivity of Plasmodium falciparum to halofantrine compared with chloroquine, quinine and mefloquine in the region of Bobo-Dioulasso, Burkina Faso (West Africa). Tropical Medicine And International Health 1998, 3: 381-4. PMID: 9623943.Peer-Reviewed Original ResearchConceptsChloroquine-resistant isolatesMean IC50 valuesChloroquine-sensitive isolatesDrug-resistant isolatesBobo-DioulassoIC50 valuesProportion of isolatesParasite densityMefloquineSignificant positive correlationHalofantrinePlasmodium falciparumNew antimalarialsCase of quinineSignificant differencesQuinineChloroquineAntimalarialsPositive correlationIsolatesBurkina FasoProportion
1996
How to perform and interpret the results of a chemoresistance test of Plasmodium falciparum in malaria patients in a tropical region.
Guiguemdé R, Gbary R, Coulibaly S, Ouedraogo J. How to perform and interpret the results of a chemoresistance test of Plasmodium falciparum in malaria patients in a tropical region. Cahiers De Santé 1996, 6: 187-91. PMID: 8764454.Peer-Reviewed Original Research
1994
Ten-year surveillance of drug-resistant malaria in Burkina Faso (1982-1991).
Guiguemde T, Aouba A, Ouedraogo J, Lamizana L. Ten-year surveillance of drug-resistant malaria in Burkina Faso (1982-1991). American Journal Of Tropical Medicine And Hygiene 1994, 50: 699-704. PMID: 8024062, DOI: 10.4269/ajtmh.1994.50.699.Peer-Reviewed Original ResearchConceptsTen-year surveillanceBobo-DioulassoDrug-resistant malariaDrug-resistant formsPrevalence of resistanceFirst caseChloroquine sensitivityVivo resistanceCases of resistanceMalaria transmissionBurkina FasoPlasmodium falciparumMefloquineHigh rateMalariaPyrimethamineChloroquineVitroVivoActive surveyLevel of resistancePrevalence
1991
Current aspects of malarial chemoresistance of subjects autochthonous in the OCCGE countries (West Africa).
Guiguemdé T, Gbary A, Ouedraogo J, Gayibor A, Lamizana L, Maiga A, Boureima H, Comlanvi C, Faye O, Niang S. Current aspects of malarial chemoresistance of subjects autochthonous in the OCCGE countries (West Africa). Tropical Medicine And International Health 1991, 71: 199-207. PMID: 1958105.Peer-Reviewed Original Research
1988
Emergence of chloroquine-resistant malaria in West Africa: the case of Sokode (Togo).
Gbary A, Guiguemdé T, Ouedraogo J. Emergence of chloroquine-resistant malaria in West Africa: the case of Sokode (Togo). Tropical Medicine And Parasitology 1988, 39: 142-4. PMID: 3051292.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsChildChild, PreschoolChloroquineDrug ResistanceHumansMalariaPlasmodium falciparumTogoConceptsDose of chloroquineVivo chloroquine resistanceChloroquine-resistant malariaThin blood smearsChloroquine resistanceChloroquine sensitivityStandard doseFever attacksWHO methodologyReference centerBlood smearsDoseMajor endemic diseaseEndemic diseaseVivo surveyWest African countriesSecond groupFirst groupMalariaChloroquineChildrenRI typeRII typeGroupAfrican countries
1987
Surveillance of the sensitivity of Plasmodium falciparum to chloroquine in Western Africa: value of in vivo tests using 5 and 10 mg/kg.
Baudon D, Guiguemde T, Ouedraogo J. Surveillance of the sensitivity of Plasmodium falciparum to chloroquine in Western Africa: value of in vivo tests using 5 and 10 mg/kg. Bulletin De La Société De Pathologie Exotique 1987, 80: 469-76. PMID: 3319257.Peer-Reviewed Original ResearchMeSH KeywordsAfrica, WesternAnimalsChildChloroquineDrug ResistanceHumansMalariaParasitologyPlasmodium falciparum