2022
Plasmodium infection is associated with cross-reactive antibodies to carbohydrate epitopes on the SARS-CoV-2 Spike protein
Lapidus S, Liu F, Casanovas-Massana A, Dai Y, Huck J, Lucas C, Klein J, Filler R, Strine M, Sy M, Deme A, Badiane A, Dieye B, Ndiaye I, Diedhiou Y, Mbaye A, Diagne C, Vigan-Womas I, Mbengue A, Sadio B, Diagne M, Moore A, Mangou K, Diallo F, Sene S, Pouye M, Faye R, Diouf B, Nery N, Costa F, Reis M, Muenker M, Hodson D, Mbarga Y, Katz B, Andrews J, Campbell M, Srivathsan A, Kamath K, Baum-Jones E, Faye O, Sall A, Vélez J, Cappello M, Wilson M, Ben-Mamoun C, Tedder R, McClure M, Cherepanov P, Somé F, Dabiré R, Moukoko C, Ouédraogo J, Boum Y, Shon J, Ndiaye D, Wisnewski A, Parikh S, Iwasaki A, Wilen C, Ko A, Ring A, Bei A. Plasmodium infection is associated with cross-reactive antibodies to carbohydrate epitopes on the SARS-CoV-2 Spike protein. Scientific Reports 2022, 12: 22175. PMID: 36550362, PMCID: PMC9778468, DOI: 10.1038/s41598-022-26709-7.Peer-Reviewed Original ResearchConceptsCross-reactive antibodiesSARS-CoV-2Positive SARS-CoV-2 antibody resultsPositive SARS-CoV-2 antibodiesSARS-CoV-2 reactivitySARS-CoV-2 antibodiesAcute malaria infectionSpike proteinAntibody test resultsPre-pandemic samplesMalaria-endemic countriesPopulation-level immunityMalaria-endemic regionsSpike S1 subunitNon-endemic countriesSARS-CoV-2 spike proteinSARS-CoV-2 proteinsPopulation-level exposureCOVID-19 transmissionMalaria exposureFalse-positive resultsMalaria infectionDisease burdenPlasmodium infectionAntibody results
2020
Different distribution of malaria parasite in left and right extremities of vertebrate hosts translates into differences in parasite transmission
Pigeault R, Isaïa J, Yerbanga R, Dabiré K, Ouédraogo J, Cohuet A, Lefèvre T, Christe P. Different distribution of malaria parasite in left and right extremities of vertebrate hosts translates into differences in parasite transmission. Scientific Reports 2020, 10: 10183. PMID: 32576924, PMCID: PMC7311528, DOI: 10.1038/s41598-020-67180-6.Peer-Reviewed Original ResearchConceptsGametocyte densityMosquito infection ratesBlood samplesInfection rateNew malaria control strategiesMajor global causeMalaria control strategiesLow parasite burdenGametocyte burdenGametocyte carriersParasite transmissionPlasmodium infectionMosquito transmission potentialRight extremitiesTransmissible stagesParasite burdenMosquito transmissionMalaria parasitesPlasmodium sppGlobal causeTransmission potentialGametocytesVector-borne diseasesDiseaseExtremities
2016
Differential Effects of Azithromycin, Doxycycline, and Cotrimoxazole in Ingested Blood on the Vectorial Capacity of Malaria Mosquitoes
Gendrin M, Yerbanga R, Ouedraogo J, Lefèvre T, Cohuet A, Christophides G. Differential Effects of Azithromycin, Doxycycline, and Cotrimoxazole in Ingested Blood on the Vectorial Capacity of Malaria Mosquitoes. Open Forum Infectious Diseases 2016, 3: ofw074. PMID: 27419152, PMCID: PMC4943539, DOI: 10.1093/ofid/ofw074.Peer-Reviewed Original ResearchIngested bloodMass drug administration programsMosquito lifespanEffect of doxycyclineDrug administration programsMosquito vectorial capacityAntibiotic treatmentMosquito microbiotaPlasmodium infectionBlood meal supplementationInfection loadVectorial capacityGut microbiotaMalaria transmissionAzithromycinMalaria parasitesPlasmodium falciparumDisease eliminationDoxycyclineMalaria vector mosquitoesAntibioticsBlood mealDifferential effectsInfection intensityMicrobiota
2014
Experimental study of the relationship between Plasmodium gametocyte density and infection success in mosquitoes; implications for the evaluation of malaria transmission-reducing interventions
Da D, Churcher T, Yerbanga R, Yaméogo B, Sangaré I, Ouedraogo J, Sinden R, Blagborough A, Cohuet A. Experimental study of the relationship between Plasmodium gametocyte density and infection success in mosquitoes; implications for the evaluation of malaria transmission-reducing interventions. Experimental Parasitology 2014, 149: 74-83. PMID: 25541384, DOI: 10.1016/j.exppara.2014.12.010.Peer-Reviewed Original ResearchConceptsGametocyte densityParasite densityBlood samplesInfected bloodMouse bloodInfectious blood samplesMembrane feeding assaysPlasmodium berghei infectionTransmission-reducing interventionsPlasmodium falciparum samplesBlood dilutionEvaluation of transmissionInfected mouse bloodBerghei infectionPlasmodium infectionMosquito infectivityAnopheles coluzzii mosquitoesInhibitory factorMonoclonal antibodiesBloodAccurate relative measuresInfectionUninfected bloodHost bloodColuzzii mosquitoes