2022
Prevalence of Plasmodium falciparum haplotypes associated with resistance to sulfadoxine–pyrimethamine and amodiaquine before and after upscaling of seasonal malaria chemoprevention in seven African countries: a genomic surveillance study
Beshir K, Muwanguzi J, Nader J, Mansukhani R, Traore A, Gamougam K, Ceesay S, Bazie T, Kolie F, Lamine M, Cairns M, Snell P, Scott S, Diallo A, Merle C, NDiaye J, Razafindralambo L, Moroso D, Ouedraogo J, Zongo I, Kessely H, Doumagoum D, Bojang K, Ceesay S, Loua K, Maiga H, Dicko A, Sagara I, Laminou I, Ogboi S, Eloike T, Milligan P, Sutherland C. Prevalence of Plasmodium falciparum haplotypes associated with resistance to sulfadoxine–pyrimethamine and amodiaquine before and after upscaling of seasonal malaria chemoprevention in seven African countries: a genomic surveillance study. The Lancet Infectious Diseases 2022, 23: 361-370. PMID: 36328000, DOI: 10.1016/s1473-3099(22)00593-x.Peer-Reviewed Original ResearchConceptsSeasonal malaria chemopreventionMalaria chemopreventionResistance-associated variantsParasite carriageSurvey-weighted prevalenceMalaria transmission seasonQuantitative PCRPrevalence ratiosP falciparumGenomic surveillance studyChemoprevention drugsBlood samplesSurveillance studyTransmission seasonChemopreventionPlasmodium falciparumAmodiaquinePrevalenceMDR1Variant haplotypeSequencing of isolatesSignificant reductionChildrenPyrimethamineCommunity survey
2021
Impact of mass administration of azithromycin as a preventive treatment on the prevalence and resistance of nasopharyngeal carriage of Staphylococcus aureus
Hema-Ouangraoua S, Tranchot-Diallo J, Zongo I, Kabore N, Nikièma F, Yerbanga R, Tinto H, Chandramohan D, Ouedraogo G, Greenwood B, Ouedraogo J. Impact of mass administration of azithromycin as a preventive treatment on the prevalence and resistance of nasopharyngeal carriage of Staphylococcus aureus. PLOS ONE 2021, 16: e0257190. PMID: 34644317, PMCID: PMC8513893, DOI: 10.1371/journal.pone.0257190.Peer-Reviewed Original ResearchConceptsAdministration of azithromycinSerious illnessS. aureusEffectiveness of azithromycinMalaria transmission seasonVulnerable pediatric populationS. aureus isolatesImpact of azithromycinNasal carriageRespiratory infectionsSulfadoxine-pyrimethaminePediatric populationClinical trialsAzithromycin resistanceNasal swabsAureus isolatesTransmission seasonAzithromycinPrevalent strainsMajor causeAdministrationPlaceboStaphylococcus aureusChildrenIllness
2019
Impact of the addition of azithromycin to antimalarials used for seasonal malaria chemoprevention on antimicrobial resistance of Streptococcus pneumoniae
Hema‐Ouangraoua S, Maiga A, Cairns M, Zongo I, Frédéric N, Yerbanga R, Tamboura B, Badji H, Gore‐Langton G, Kuepfer I, Tinto H, Sagara I, Dicko A, Sow S, Chandrahoman D, Greenwood B, Ouedraogo J. Impact of the addition of azithromycin to antimalarials used for seasonal malaria chemoprevention on antimicrobial resistance of Streptococcus pneumoniae. Tropical Medicine And International Health 2019, 24: 1442-1454. PMID: 31655020, PMCID: PMC7687265, DOI: 10.1111/tmi.13321.Peer-Reviewed Original ResearchConceptsSeasonal malaria chemopreventionAddition of azithromycinMalaria chemopreventionNasopharyngeal swabsStreptococcus pneumoniaeAnnual malaria transmission seasonsMalaria transmission seasonResistance of pneumococciMalian childrenHospital admissionAzithromycin 1Nasal isolatesAntimalarial combinationLast administrationPneumococcal isolatesTransmission seasonDrug AdministrationAzithromycinChemopreventionResistant isolatesAntimalarialsAntimicrobial resistancePlaceboBurkina FasoChildrenOptimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children
Chotsiri P, Zongo I, Milligan P, Compaore Y, Somé A, Chandramohan D, Hanpithakpong W, Nosten F, Greenwood B, Rosenthal P, White N, Ouédraogo J, Tarning J. Optimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children. Nature Communications 2019, 10: 480. PMID: 30696903, PMCID: PMC6351525, DOI: 10.1038/s41467-019-08297-9.Peer-Reviewed Original ResearchConceptsSeasonal malaria chemopreventionMalaria chemopreventionSmall childrenPlasmodium falciparum malariaHigh transmission seasonLower drug exposureSigmoidal Emax modelHigh transmission periodYoung childrenAlternative regimenFalciparum malariaDose scheduleMonthly dosesOptimal dosingDrug exposurePreventive efficacyTransmission seasonPharmacokinetic parametersBody weightEmax modelMalaria incidenceVulnerable populationsHigh dosageChildrenChemoprevention
2017
Predictors and pathways of language and motor development in four prospective cohorts of young children in Ghana, Malawi, and Burkina Faso
Prado E, Abbeddou S, Adu‐Afarwuah S, Arimond M, Ashorn P, Ashorn U, Bendabenda J, Brown K, Hess S, Kortekangas E, Lartey A, Maleta K, Oaks B, Ocansey E, Okronipa H, Ouédraogo J, Pulakka A, Somé J, Stewart C, Stewart R, Vosti S, Jimenez E, Dewey K. Predictors and pathways of language and motor development in four prospective cohorts of young children in Ghana, Malawi, and Burkina Faso. Journal Of Child Psychology And Psychiatry 2017, 58: 1264-1275. PMID: 28543426, PMCID: PMC5697619, DOI: 10.1111/jcpp.12751.Peer-Reviewed Original ResearchConceptsEarly child developmentIron statusMotor developmentProspective cohortPonderal growthAcute respiratory infectionsInternational LipidMaternal illnessExclusive breastfeedingMiddle-income countriesRespiratory infectionsPrevious reviewsMonths postpartumRisk factorsChild diarrheaCohortDesign of interventionsSocioeconomic statusCaregiver activitiesChild developmentPregnancyYoung childrenBurkina FasoDietary diversityChildren
2016
Linear Growth and Child Development in Burkina Faso, Ghana, and Malawi
Prado E, Abbeddou S, Adu-Afarwuah S, Arimond M, Ashorn P, Ashorn U, Brown K, Hess S, Lartey A, Maleta K, Ocansey E, Ouédraogo J, Phuka J, Somé J, Vosti S, Jimenez E, Dewey K. Linear Growth and Child Development in Burkina Faso, Ghana, and Malawi. Pediatrics 2016, 138: e20154698. PMID: 27474016, DOI: 10.1542/peds.2015-4698.Peer-Reviewed Original ResearchConceptsPersonal-social developmentDevelopmental stimulationAge z-scoreAge 18 monthsMaternal supplementationLinear growthNutritional supplementationGrowth falteringEarly infancyZ-scoreMotor developmentAdjusted estimatesBurkina FasoMonthsBirthChild developmentMotor skillsChildrenSDAssociationExecutive functionSupplementationStimulationExecutive function developmentPoor developmentLipid-Based Nutrient Supplements Plus Malaria and Diarrhea Treatment Increase Infant Development Scores in a Cluster-Randomized Trial in Burkina Faso 1–3
Prado E, Abbeddou S, Yakes Jimenez E, Somé J, Ouédraogo Z, Vosti S, Dewey K, Brown K, Hess S, Ouédraogo J. Lipid-Based Nutrient Supplements Plus Malaria and Diarrhea Treatment Increase Infant Development Scores in a Cluster-Randomized Trial in Burkina Faso 1–3. Journal Of Nutrition 2016, 146: 814-822. PMID: 26962193, DOI: 10.3945/jn.115.225524.Peer-Reviewed Original ResearchAge 18 moPersonal-social developmentRural Burkina FasoSQ-LNSsIC groupLipid-based nutrient supplementsInfant Development scoresAge 9Treatment of malariaRapid brain developmentNutrient supplementsSecondary outcomesPlacebo tabletsAdequate nutritionIC subgroupBrain developmentIC childrenMalariaNonintervention cohortInfant developmentTrialsDevelopment scoresBurkina FasoChildrenTreatment
2015
Randomized Noninferiority Trial of Dihydroartemisinin-Piperaquine Compared with Sulfadoxine-Pyrimethamine plus Amodiaquine for Seasonal Malaria Chemoprevention in Burkina Faso
Zongo I, Milligan P, Compaore Y, Some A, Greenwood B, Tarning J, Rosenthal P, Sutherland C, Nosten F, Ouedraogo J. Randomized Noninferiority Trial of Dihydroartemisinin-Piperaquine Compared with Sulfadoxine-Pyrimethamine plus Amodiaquine for Seasonal Malaria Chemoprevention in Burkina Faso. Antimicrobial Agents And Chemotherapy 2015, 59: 4387-4396. PMID: 25918149, PMCID: PMC4505196, DOI: 10.1128/aac.04923-14.Peer-Reviewed Original ResearchConceptsSeasonal malaria chemopreventionMalaria chemopreventionAlternative drugsControl groupPrimary outcome measureSeasonal malaria transmissionRandomized noninferiority trialPotential alternative drugDihydroartemisinin-PiperaquinePfdhps mutationsClinical malariaMalaria attacksSulfadoxine-pyrimethamineOdds ratioNoninferiority trialOutcome measuresDHAPQChildren 3Malaria transmissionDrug resistanceAntifolate resistanceChemopreventionChildrenAmodiaquineTrialsTreated Malaria Does Not Affect Physical Growth And Hemoglobin Concentration of Young Children in Burkina Faso
Some J, Abbeddou S, Jimenez E, Hess S, Ouedraogo Z, Guissou R, Vosti S, Ouedraogo J, Brown K. Treated Malaria Does Not Affect Physical Growth And Hemoglobin Concentration of Young Children in Burkina Faso. The FASEB Journal 2015, 29 DOI: 10.1096/fasebj.29.1_supplement.757.7.Peer-Reviewed Original ResearchLipid-based nutrient supplementationRapid diagnostic testsPhysical growthHemoglobin concentrationZ-scoreYoung Burkinabe childrenLength z-scoreCause of anemiaAssociation of malariaAge z-scoreYoung childrenMo of ageMalaria episodesMorbidity assessmentBurkinabe childrenMean changeMalariaDiagnostic testsDifferent dosesEarly childhoodChildrenDiarrheaFeverEpisodesFrequency categories
2014
Burkinabe infants given small quantity lipid‐based nutrient supplements and illness treatment in infancy score higher in motor, language, and personal‐social development (251.1)
Prado E, Abbeddou S, Jimenez E, Somé J, Ouédraogo Z, Vosti S, Dewey K, Hess S, Ouédraogo J, Brown K. Burkinabe infants given small quantity lipid‐based nutrient supplements and illness treatment in infancy score higher in motor, language, and personal‐social development (251.1). The FASEB Journal 2014, 28 DOI: 10.1096/fasebj.28.1_supplement.251.1.Peer-Reviewed Original ResearchSmall-quantity lipid-based nutrient supplementsLipid-based nutrient supplementsPersonal-social developmentNon-intervention communitiesYoung Burkinabe childrenTreatment of malariaMonths of ageRural Burkina FasoNutrient supplementsSQ-LNSBurkinabe childrenIllness treatmentBrain growthAdequate nutritionMacronutrient metabolismBrain developmentIC childrenMelinda Gates FoundationDevelopment of motorChildrenMalariaLowest decileTreatmentGrant funding sourcesSDAdherence to small‐quantity lipid based nutrient supplement among young Burkinabe children (624.19)
Abbeddou S, Hess S, Jimenez E, Somé J, Guissou R, Ouedraogo Z, Vosti S, Ouedraogo J, Brown K. Adherence to small‐quantity lipid based nutrient supplement among young Burkinabe children (624.19). The FASEB Journal 2014, 28 DOI: 10.1096/fasebj.28.1_supplement.624.19.Peer-Reviewed Original ResearchSQ-LNSDays/weekHome visitsSmall-quantity lipid-based nutrient supplementsLipid-based nutrient supplementsSmall-Quantity LipidYoung Burkinabe childrenRandomized clinical trialsReporting of adherenceWeekly home visitsDisappearance rateWeekly adherenceNutrient supplementsBurkinabe childrenClinical trialsSupplementation regimensCaregiver interviewsFull doseHome ObservationMelinda Gates FoundationOlder childrenObservation periodAdherenceChildrenGrant funding sources
2013
Comparison of field-based xenodiagnosis and direct membrane feeding assays for evaluating host infectiousness to malaria vector Anopheles gambiae
Gouagna L, Yao F, Yameogo B, Dabiré R, Ouédraogo J. Comparison of field-based xenodiagnosis and direct membrane feeding assays for evaluating host infectiousness to malaria vector Anopheles gambiae. Acta Tropica 2013, 130: 131-139. PMID: 24262642, DOI: 10.1016/j.actatropica.2013.10.022.Peer-Reviewed Original ResearchConceptsMosquito bitesOocyst infectionDirect membrane feeding assaysInfectious mosquito bitesAnopheles mosquitoesMembrane feeding assaysMalaria-endemic areasLow gametocyte densitiesCross-sectional surveyGametocyte densityEndemic areasDay 7Classical microscopic examinationHost infectiousnessBlood smearsOocyst prevalenceXenodiagnosisHost skinMembrane feederInfectionInfectious individualsInfectiousnessMicroscopic examinationHuman subjectsChildrenThe effects of the acute phase response on biomarkers of iron status differ in the presence of malaria infection
Wessells R, Hess S, Ouedraogo Z, Rouamba N, Erhardt J, Ouedraogo J, Brown K. The effects of the acute phase response on biomarkers of iron status differ in the presence of malaria infection. The FASEB Journal 2013, 27: 107.7-107.7. DOI: 10.1096/fasebj.27.1_supplement.107.7.Peer-Reviewed Original ResearchC-reactive proteinAcute phase responseIron statusAsymptomatic childrenSubclinical inflammationPlasma ferritinMalaria infectionMalarial parasitemiaPhase responseHigh prevalenceHigher geometric meanMalariaPrevalenceAP proteinInflammationChildrenInfectionGrant funding sourcesDeficiencyAGPGeometric meanStatusAntigenemiaBurkina FasoParasitemia
2012
Vitamin A supplementation of young children in Burkina Faso, and risk factors for non‐coverage
Hess S, Ouédraogo C, Wilson S, Prince L, Rouamba N, Ouédraogo J, Vosti S, Dakkak M, Brown K. Vitamin A supplementation of young children in Burkina Faso, and risk factors for non‐coverage. The FASEB Journal 2012, 26: 1031.4-1031.4. DOI: 10.1096/fasebj.26.1_supplement.1031.4.Peer-Reviewed Original ResearchVitamin A supplementsVAS coverageChildren 6High-dose vitamin A supplementsThrasher Research FundYoung mothersCross-sectional household surveyHealth districtRisk factorsA supplementsBurkina FasoAge rangeChildrenYoung childrenSpecific targetingCaregiversStaff trainingMothersHousehold surveySupplementation
2011
The effect of zinc supplementation, provided as either a liquid ZnSO4 solution or a dispersible tablet, on plasma zinc concentration among young Burkinabé children
Wessells R, Ouédraogo Z, Rouamba N, Hess S, Ouédraogo J, Brown K. The effect of zinc supplementation, provided as either a liquid ZnSO4 solution or a dispersible tablet, on plasma zinc concentration among young Burkinabé children. The FASEB Journal 2011, 25: 236.1-236.1. DOI: 10.1096/fasebj.25.1_supplement.236.1.Peer-Reviewed Original ResearchPlasma zinc concentrationPlacebo groupZinc supplementationZinc supplementsPreventive zinc supplementationDispersible tabletsCause mortalityZinc concentrationsZn concPlacebo solutionChildren 6Study populationDaily supplementSD changeWeight gainZinc deficiencyZn supplementsFurther studiesYoung childrenDifferential changesSupplementationSupplementsChildrenGroupZinc sulfate
2010
Acceptability of zinc‐fortified, lipid‐based nutrient supplements (LNS) prepared for young children in Burkina Faso
Hess S, Bado L, Aaron G, Ouédraogo J, Zeilani M, Brown K. Acceptability of zinc‐fortified, lipid‐based nutrient supplements (LNS) prepared for young children in Burkina Faso. Maternal And Child Nutrition 2010, 7: 357-367. PMID: 21159124, PMCID: PMC6860760, DOI: 10.1111/j.1740-8709.2010.00287.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBurkina FasoConsumer BehaviorDietary FatsDietary SupplementsDose-Response Relationship, DrugFemaleFocus GroupsHumansInfantInfant FoodInfant Nutritional Physiological PhenomenaInterviews as TopicMaleMicronutrientsNutritive ValueSocioeconomic FactorsSurveys and QuestionnairesYoung AdultZincConceptsLipid-based nutrient supplementsAcceptability studyYoung childrenPublic health concernPossible adverse effectsNutrient supplementsNutritional statusComplementary foodsChildren 9Health concernLow-income countriesMaternal reportsAdverse effectsTrialsChildren's consumptionMicronutrient deficienciesMothersChildrenGood acceptabilityDoseDetectable differenceTime of consumptionSupplementsNovel strategyDetection of differences
2002
Chloroquine and sulphadoxine‐pyrimethamine efficacy for uncomplicated malaria treatment and haematological recovery in children in Bobo‐Dioulasso, Burkina Faso during a 3‐year period 1998–2000
Tinto H, Zoungrana E, Coulibaly S, Ouedraogo J, Traoré M, Guiguemde T, Van Marck E, D'Alessandro U. Chloroquine and sulphadoxine‐pyrimethamine efficacy for uncomplicated malaria treatment and haematological recovery in children in Bobo‐Dioulasso, Burkina Faso during a 3‐year period 1998–2000. Tropical Medicine And International Health 2002, 7: 925-930. PMID: 12390597, DOI: 10.1046/j.1365-3156.2002.00952.x.Peer-Reviewed Original ResearchConceptsPrevalence of anemiaClinical failureParasitological resistancePacked cell volumeUncomplicated malariaDay 14Day 0Uncomplicated malaria treatmentHaematological recoveryMalaria treatmentCQ resistanceHealth centersRegular surveillanceAntimalarial drugsChloroquineBurkina FasoPrevalenceBobo-DioulassoChildrenAnemiaEvidence of increasesMalariaTreatmentFailureCell volume
1997
Esquisse d'une méthode d'estimation du coût économique chiffré des accès palustres: application à une zone rurale au Burkina Faso (Afrique de l'Ouest)
Guiguemdé T, Coulibaly N, Coulibaly S, Ouedraogo J, Gbary A. Esquisse d'une méthode d'estimation du coût économique chiffré des accès palustres: application à une zone rurale au Burkina Faso (Afrique de l'Ouest). Tropical Medicine And International Health 1997, 2: 646-653. PMID: 9289349, DOI: 10.1046/j.1365-3156.1997.d01-351.x.Peer-Reviewed Original ResearchConceptsDuration of illnessIndirect costsDirect costsHealth center clientsCosts of malariaAccount direct costsAge of subjectsMost patientsConsultation feesAverage durationDegree of invalidityMicroscopic examinationBurkina FasoCenter clientsIllnessMalariaAdultsChildrenYearsDurationMedicationsRural areasPatients
1992
Variation of the parasite density of Plasmodium falciparum in asymptomatic carriers: consequences for malaria chemoresistance studies.
Guiguemde T, Toe A, Sadeler B, Gbary A, Ouedraogo J, Louboutin-Croc J. Variation of the parasite density of Plasmodium falciparum in asymptomatic carriers: consequences for malaria chemoresistance studies. Medecine Tropicale 1992, 52: 313-5. PMID: 1435194.Peer-Reviewed Original ResearchConceptsDay 4Parasite densityDay 0Plasmodium falciparumAsymptomatic peopleAsymptomatic carriersInclusion criteriaMalaria prevalenceStudy 16Drug absorptionPrimary school childrenParasitaemiaBobo-DioulassoNycthemeral variationsFurther studiesSignificant differencesChildrenSchool childrenVivo testsFalciparumNegativationChemosensitivityGreater numberPrevalenceChemoresistance
1988
Emergence of chloroquine-resistant malaria in West Africa: the case of Sokode (Togo).
Gbary A, Guiguemdé T, Ouedraogo J. Emergence of chloroquine-resistant malaria in West Africa: the case of Sokode (Togo). Tropical Medicine And Parasitology 1988, 39: 142-4. PMID: 3051292.Peer-Reviewed Original ResearchConceptsDose of chloroquineVivo chloroquine resistanceChloroquine-resistant malariaThin blood smearsChloroquine resistanceChloroquine sensitivityStandard doseFever attacksWHO methodologyReference centerBlood smearsDoseMajor endemic diseaseEndemic diseaseVivo surveyWest African countriesSecond groupFirst groupMalariaChloroquineChildrenRI typeRII typeGroupAfrican countries