2016
Protocol for a population-based molecular epidemiology study of tuberculosis transmission in a high HIV-burden setting: the Botswana Kopanyo study
Zetola N, Modongo C, Moonan P, Click E, Oeltmann J, Shepherd J, Finlay A, Basotli J, Bile E, Boyd R, Mbashi D, Fane O, Shin S, Surie D, Cowger V, Matsire O, Posey J, Serumola C, Tobias J. Protocol for a population-based molecular epidemiology study of tuberculosis transmission in a high HIV-burden setting: the Botswana Kopanyo study. BMJ Open 2016, 6: e010046. PMID: 27160840, PMCID: PMC4874111, DOI: 10.1136/bmjopen-2015-010046.Peer-Reviewed Original ResearchConceptsTB transmissionHIV infectionHigh HIV burden settingsPopulation-based molecular epidemiology studiesHIV burden settingsTuberculosis index casesAirborne droplet nucleiHigh rateMolecular epidemiology studiesMtb transmissionIndependent review boardTuberculosis transmissionUS CentersRecent transmissionHigh riskIndex caseLow prevalenceMTB isolatesParticipants' residencesEthical approvalEpidemiology studiesDisease controlHIVReview boardMycobacterium tuberculosis
2014
Increase in anti-tuberculosis drug resistance in Botswana: results from the fourth National Drug Resistance Survey
Menzies H, Moalosi G, Anisimova V, Gammino V, Sentle C, Bachhuber M, Bile E, Radisowa K, Kachuwaire O, Basotli J, Maribe T, Makombe R, Shepherd J, Kim B, Samandari T, El-Halabi S, Chirenda J, Cain K. Increase in anti-tuberculosis drug resistance in Botswana: results from the fourth National Drug Resistance Survey. The International Journal Of Tuberculosis And Lung Disease 2014, 18: 1026-1033. PMID: 25189548, PMCID: PMC5531285, DOI: 10.5588/ijtld.13.0749.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAntitubercular AgentsBotswanaChildChild, PreschoolDrug Resistance, Multiple, BacterialFemaleHealth Care SurveysHumansMaleMicrobial Sensitivity TestsMiddle AgedMycobacterium tuberculosisSputumTime FactorsTreatment OutcomeTuberculosis, Multidrug-ResistantTuberculosis, PulmonaryYoung AdultConceptsAnti-tuberculosis drug resistanceMultidrug-resistant tuberculosisPrevious anti-tuberculosis treatmentAnti-tuberculosis treatmentNew TB patientsDrug resistance surveyTB patientsDrug susceptibility testingDrug resistanceNew sputum smear-positive TB patientsAnti-tuberculosis drug susceptibility testingSputum smear-positive TB patientsNational drug resistance surveyHigh TB burden countriesMDR-TB diagnosisPositive TB patientsDrug-resistant TBTB burden countriesResistance surveyEmergence of resistanceTB controlBurden countriesDST resultsNew patientsMycobacterial culture
1994
Peptide length and sequence specificity of the mouse TAP1/TAP2 translocator.
Schumacher T, Kantesaria D, Heemels M, Ashton-Rickardt P, Shepherd J, Fruh K, Yang Y, Peterson P, Tonegawa S, Ploegh H. Peptide length and sequence specificity of the mouse TAP1/TAP2 translocator. Journal Of Experimental Medicine 1994, 179: 533-540. PMID: 8294864, PMCID: PMC2191358, DOI: 10.1084/jem.179.2.533.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateAmino Acid SequenceAnimalsATP Binding Cassette Transporter, Subfamily B, Member 2ATP Binding Cassette Transporter, Subfamily B, Member 3ATP-Binding Cassette TransportersBinding, CompetitiveBiological TransportCarrier ProteinsFemaleHistocompatibility Antigens Class IIMiceMice, Inbred C57BLMolecular Sequence DataPeptidesTemperature
1993
TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective
Shepherd J, Schumacher T, Ashton-Rickardt P, Imaeda S, Ploegh H, Janeway C, Tonegawa S. TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective. Cell 1993, 74: 577-584. PMID: 8348620, DOI: 10.1016/0092-8674(93)80058-m.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateAmino Acid SequenceAnimalsATP Binding Cassette Transporter, Subfamily B, Member 2ATP-Binding Cassette TransportersBiological TransportCarrier ProteinsCrosses, GeneticHistocompatibility Antigens Class IIMiceMice, Inbred C57BLMice, Inbred StrainsMicrosomesMicrosomes, LiverMolecular Sequence DataOligopeptidesPeptidesPoly I-CSpleenThymus GlandT-Lymphocytes