2015
Heart rate is associated with progression of atrial fibrillation, independent of rhythm
Holmqvist F, Kim S, Steinberg BA, Reiffel JA, Mahaffey KW, Gersh BJ, Fonarow GC, Naccarelli GV, Chang P, Freeman JV, Kowey PR, Thomas L, Peterson ED, Piccini JP. Heart rate is associated with progression of atrial fibrillation, independent of rhythm. Heart 2015, 101: 894. PMID: 25732748, PMCID: PMC4453487, DOI: 10.1136/heartjnl-2014-307043.Peer-Reviewed Original ResearchConceptsAtrial fibrillationAF progressionHeart rateBaseline ECGRhythm control strategyBetter Informed TreatmentPredictors of progressionPersistent atrial fibrillationModest discriminatory powerLower heart rateHigher heart rateMore comorbiditiesOutcomes RegistryPatientsClinical practiceInformed TreatmentProgressionStrongest predictorFibrillationPredictorsBaselineAgeECGSustained formsSignificant interaction
2007
Novel predictor of prognosis from exercise stress testing: Heart rate variability response to the exercise treadmill test
Dewey FE, Freeman JV, Engel G, Oviedo R, Abrol N, Ahmed N, Myers J, Froelicher VF. Novel predictor of prognosis from exercise stress testing: Heart rate variability response to the exercise treadmill test. American Heart Journal 2007, 153: 281-288. PMID: 17239690, DOI: 10.1016/j.ahj.2006.11.001.Peer-Reviewed Original ResearchConceptsHeart rate variabilitySquare successive differenceCardiovascular mortalityPrognostic powerHF powerExercise treadmill testingRoot mean square successive differenceFrequency-domain HRV analysisExercise stress testingExercise treadmill testMortality end pointsSuccessive differencesStandard exercise testingHeart rate variability responsesMinutes of recoveryStrongest predictorLow-frequency powerMean square successive differenceHigh-frequency powerR interval dataCardiovascular deathCause mortalityPeak exerciseClinical factorsExercise testing