2005
Connexin26 is responsible for anionic molecule permeability in the cochlea for intercellular signalling and metabolic communications
Zhao H. Connexin26 is responsible for anionic molecule permeability in the cochlea for intercellular signalling and metabolic communications. European Journal Of Neuroscience 2005, 21: 1859-1868. PMID: 15869481, PMCID: PMC2548270, DOI: 10.1111/j.1460-9568.2005.04031.x.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateAffinity LabelsAnimalsAnionsAnti-Inflammatory AgentsCalciumCationsCell CommunicationCell CountCell Membrane PermeabilityCells, CulturedCochleaConnexin 26ConnexinsDose-Response Relationship, DrugEnzyme InhibitorsFluorescent DyesGap JunctionsGlycyrrhetinic AcidGuinea PigsIntracellular MembranesPlatelet Aggregation InhibitorsProadifenPyridoxal PhosphateSpectrometry, FluorescenceTime FactorsConceptsCharge selectivityLarge pore sizeCationic fluorescent dyeIntercellular signalingAnionic dyesDye sizeGap junctionsMetabolic communicationPore sizeMolecule permeabilityMolecular permeabilitySelectivityEnergy moleculesCationic probePassage of ionsFluorescent dyeGap junctional permeabilityMoleculesCochlear sensory epitheliumDyeCochlear gap junctions
2001
Chlorpromazine Alters Outer Hair Cell Electromotility
Lue A, Zhao H, Brownell W. Chlorpromazine Alters Outer Hair Cell Electromotility. Otolaryngology 2001, 125: 71-76. PMID: 11458218, DOI: 10.1067/mhn.2001.116446.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell MovementCells, CulturedChlorpromazineCochleaDose-Response Relationship, DrugElectric ConductivityFemaleGuinea PigsHair Cells, Auditory, OuterMaleMembrane PotentialsSensitivity and SpecificityConceptsOuter hair cellsHair cellsDose-dependent depolarizationGuinea pig outer hair cellsEffect of chlorpromazineElectromotile responseAntipsychotic medicationChlorpromazine treatmentHearing thresholdsLarge dosesCochlear sensitivityOtoacoustic emissionsInner earChlorpromazineOuter Hair Cell ElectromotilityHair cell electromotilityOHC electromotilityMembrane voltageRecording conditionsCellsMedicationsResponseElectromotility