Holly Grossetta Nardini, AHIP
Associate DirectorCards
About
Research
Publications
2023
Systematic review and meta-analysis of the genetics of peripheral arterial disease
Ochoa Chaar C, Kim T, Alameddine D, DeWan A, Guzman R, Dardik A, Grossetta Nardini H, Wallach J, Kullo I, Murray M. Systematic review and meta-analysis of the genetics of peripheral arterial disease. JVS Vascular Science 2023, 5: 100133. PMID: 38314202, PMCID: PMC10832467, DOI: 10.1016/j.jvssci.2023.100133.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsGenome-wide association studiesDNA variantsWide association studyRecent genome-wide association studiesSmall candidate gene studiesCandidate gene studiesGWAS studiesCandidate genesAssociation studiesGene studiesGenetic researchGeneticsOnly variantVariantsHepatic lipaseGenesProgressionSignificant variation
2021
Evidence synthesis papers would benefit from segmented peer review
Nyhan K, Nardini H. Evidence synthesis papers would benefit from segmented peer review. Translational Oncology 2021, 14: 101060. PMID: 33706230, PMCID: PMC7944096, DOI: 10.1016/j.tranon.2021.101060.Commentaries, Editorials and Letters
2020
Long-term natural history of visual acuity in eyes with choroideremia: a systematic review and meta-analysis of data from 1004 individual eyes
Shen LL, Ahluwalia A, Sun M, Young BK, Nardini H, Del Priore LV. Long-term natural history of visual acuity in eyes with choroideremia: a systematic review and meta-analysis of data from 1004 individual eyes. British Journal Of Ophthalmology 2020, 105: 271-278. PMID: 32471821, PMCID: PMC7704705, DOI: 10.1136/bjophthalmol-2020-316028.Peer-Reviewed Original ResearchConceptsBest-corrected visual acuityLong-term natural historyHorizontal translation factorPrimary endpointVisual acuityNatural historyCommon primary endpointBCVA declineYounger patientsUntreated eyesFuture trialsTreatment trialsAge 39Transition ageSystematic reviewFunction of ageIndividual eyesChoroideremiaAgeEndpointSole endpointEyesPatientsAcuityDisease biomarkersProgression of Unifocal versus Multifocal Geographic Atrophy in Age-Related Macular Degeneration A Systematic Review and Meta-analysis
Shen LL, Sun M, Grossetta Nardini HK, Del Priore LV. Progression of Unifocal versus Multifocal Geographic Atrophy in Age-Related Macular Degeneration A Systematic Review and Meta-analysis. Ophthalmology Retina 2020, 4: 899-910. PMID: 32423772, PMCID: PMC7483721, DOI: 10.1016/j.oret.2020.03.020.Peer-Reviewed Original ResearchConceptsMultifocal geographic atrophyGeographic atrophyMacular Degeneration A Systematic ReviewNonexudative age-related macular degenerationAge-related macular degenerationHorizontal translation factorPrognosis Studies toolSignificant prognostic factorsA Systematic ReviewColor fundus photographyGA growth rateMultifocal groupPrognostic factorsFundus autofluorescenceGA patientsFundus photographyEgger's testMacular degenerationStudy qualityFunnel plotSystematic reviewMeta-AnalysisPublication biasGA lesionsLesion perimeterLong-term Natural History of Atrophy in Eyes with Choroideremia—A Systematic Review and Meta-analysis of Individual-Level Data
Shen LL, Ahluwalia A, Sun M, Young BK, Grossetta Nardini HK, Del Priore LV. Long-term Natural History of Atrophy in Eyes with Choroideremia—A Systematic Review and Meta-analysis of Individual-Level Data. Ophthalmology Retina 2020, 4: 840-852. PMID: 32362554, PMCID: PMC7415675, DOI: 10.1016/j.oret.2020.03.003.Peer-Reviewed Original ResearchConceptsResidual retinal pigment epitheliumLong-term natural historyHorizontal translation factorFundus autofluorescenceRPE areaNatural historyUntreated eyesSystematic reviewPrognosis Studies toolRisk of biasRetinal pigment epitheliumLog-transformed areaAnatomic endpointsPatient ageRPE changesTreatment trialsDisease progressionAnatomic measuresPigment epitheliumMeta-AnalysisLiterature databasesIndividual eyesCross-sectional dataChoroideremiaAtrophyUpdating insights into rosiglitazone and cardiovascular risk through shared data: individual patient and summary level meta-analyses
Wallach JD, Wang K, Zhang AD, Cheng D, Grossetta Nardini HK, Lin H, Bracken MB, Desai M, Krumholz HM, Ross JS. Updating insights into rosiglitazone and cardiovascular risk through shared data: individual patient and summary level meta-analyses. The BMJ 2020, 368: l7078. PMID: 32024657, PMCID: PMC7190063, DOI: 10.1136/bmj.l7078.Peer-Reviewed Original ResearchConceptsIndividual patient-level dataCardiovascular related deathsCardiovascular riskMyocardial infarctionRelated deathsSummary-level dataHeart failureOdds ratioSystematic reviewIncreased cardiovascular riskMore myocardial infarctionsHeart failure eventsCochrane Central RegistryAcute myocardial infarctionMyocardial infarction eventsPatient-level dataRandom-effects modelWeb of ScienceAnalysis of trialsEligible trialsComposite outcomeAdverse eventsContinuity correctionControlled TrialsRosiglitazone treatmentTopographic Variation of the Growth Rate of Geographic Atrophy in Nonexudative Age-Related Macular Degeneration: A Systematic Review and Meta-analysis
Shen LL, Sun M, Khetpal S, Nardini H, Del Priore LV. Topographic Variation of the Growth Rate of Geographic Atrophy in Nonexudative Age-Related Macular Degeneration: A Systematic Review and Meta-analysis. Investigative Ophthalmology & Visual Science 2020, 61: 2. PMID: 31995152, PMCID: PMC7205189, DOI: 10.1167/iovs.61.1.2.Peer-Reviewed Original Research
2019
Librarians as methodological peer reviewers for systematic reviews: results of an online survey
Grossetta Nardini HK, Batten J, Funaro MC, Garcia-Milian R, Nyhan K, Spak JM, Wang L, Glover JG. Librarians as methodological peer reviewers for systematic reviews: results of an online survey. Research Integrity And Peer Review 2019, 4: 23. PMID: 31798974, PMCID: PMC6882225, DOI: 10.1186/s41073-019-0083-5.Peer-Reviewed Original ResearchRECLASSIFICATION OF FUNDUS AUTOFLUORESCENCE PATTERNS SURROUNDING GEOGRAPHIC ATROPHY BASED ON PROGRESSION RATE
Shen LL, Liu F, Nardini HG, Del Priore LV. RECLASSIFICATION OF FUNDUS AUTOFLUORESCENCE PATTERNS SURROUNDING GEOGRAPHIC ATROPHY BASED ON PROGRESSION RATE. Retina 2019, Publish Ahead of Print: &na;. PMID: 30829988, DOI: 10.1097/iae.0000000000002480.Peer-Reviewed Original ResearchConceptsGA progression ratesFAF patternsGeographic atrophyProgression rateHorizontal translation factorFundus autofluorescence patternsDifferent entry timesLesion progression ratesFundus autofluorescenceCochrane LibraryClinical trialsAutofluorescence patternsGroup 2Group 1Group 3Group 4Natural historyAtrophyGroupRadius growth rateYearsEMBASEMEDLINEPubMedNatural History of Autosomal Recessive Stargardt Disease in Untreated Eyes A Systematic Review and Meta-analysis of Study- and Individual-Level Data
Shen LL, Sun M, Grossetta Nardini HK, Del Priore LV. Natural History of Autosomal Recessive Stargardt Disease in Untreated Eyes A Systematic Review and Meta-analysis of Study- and Individual-Level Data. Ophthalmology 2019, 126: 1288-1296. PMID: 31227323, DOI: 10.1016/j.ophtha.2019.05.015.Peer-Reviewed Original ResearchConceptsBaseline lesion sizeHorizontal translation factorAutosomal recessive Stargardt diseaseRecessive Stargardt diseaseLog-transformed areaLesion sizeUntreated eyesAtrophic lesionsStargardt diseaseSystematic reviewNatural historyOnset of symptomsNewcastle-Ottawa ScaleRisk of biasReliable outcome measuresIndividual-level dataAtrophy progressionFundus autofluorescenceInclusion criteriaOutcome measuresMeta-AnalysisLesion onsetProgression patternsLiterature databasesLesions
Academic Achievements & Community Involvement
News & Links
News
- September 01, 2022Source: Harvey Cushing/John Hay Whitney Medical Library News
Holly Grossetta Nardini Selected as NLM/AAHSL Leadership Fellow
- July 30, 2018
Holly Grossetta Nardini Receives Estelle Brodman Academic Medical Librarian of the Year Award
- April 30, 2017
Library provides new tool to speed and improve systematic reviews