1995
Nitric oxide synthase inhibition and extracellular glutamate concentration after cerebral ischemia/reperfusion.
Zhang J, Benveniste H, Klitzman B, Piantadosi C. Nitric oxide synthase inhibition and extracellular glutamate concentration after cerebral ischemia/reperfusion. Stroke 1995, 26: 298-304. PMID: 7530389, DOI: 10.1161/01.str.26.2.298.Peer-Reviewed Original ResearchConceptsIschemia/reperfusionBlood-brain barrierCerebral blood flowBrain ischemia/reperfusionExcitatory amino acidsExtracellular glutamate concentrationL-NAMEBlood flowGlutamate concentrationSynthase inhibitionL-arginineExcitatory amino acid toxicityL-NAME-treated ratsPostischemic cerebral blood flowNitric oxide synthase inhibitionCerebral ischemia/reperfusionBlood-brain barrier functionL-arginine methyl esterCerebral blood flow responseBlood-brain barrier permeabilityGlobal brain ischemia/reperfusionElevated glutamate concentrationsImmediate postischemic periodInterstitial glutamate concentrationL-NAME administration
1991
MR imaging of microcirculation in rat brain: Correlation with carbon dioxide‐induced changes in blood flow
Maki J, Benveniste H, Macfall J, Piantadosi C, Johnson G. MR imaging of microcirculation in rat brain: Correlation with carbon dioxide‐induced changes in blood flow. Journal Of Magnetic Resonance Imaging 1991, 1: 673-681. PMID: 1823172, DOI: 10.1002/jmri.1880010609.Peer-Reviewed Original ResearchConceptsCerebral blood flowRat cerebral blood flowBlood flowArterial carbon dioxide pressureLaser Doppler flowmetry studyMR imaging studiesMagnetic resonance imaging techniquesRat brainLDF valuesCarbon dioxide pressureImaging studiesMR imagingTissue microcirculationImaging valuesPaCO2MicrocirculationQualitative pictureMotion sensitivityPresent studyCarbon dioxide-induced changeImaging techniquesFC techniqueRat motionsGradient coilsImagingDiffusion/microcirculation MRI in the rat brain
Macfall J, Maki J, Johnson G, Hedlund L, Benveniste H, Copher G. Diffusion/microcirculation MRI in the rat brain. Magnetic Resonance In Medicine 1991, 19: 305-310. PMID: 1908936, DOI: 10.1002/mrm.1910190219.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrainCarbon DioxideCerebrovascular CirculationDiffusionMagnetic Resonance ImagingMicrocirculationRatsRats, Inbred Strains
1987
Regional Cerebral Glucose Phosphorylation and Blood Flow After Insertion of a Microdialysis Fiber Through the Dorsal Hippocampus in the Rat
Benveniste H, Drejer J, Schousboe A, Diemer N. Regional Cerebral Glucose Phosphorylation and Blood Flow After Insertion of a Microdialysis Fiber Through the Dorsal Hippocampus in the Rat. Journal Of Neurochemistry 1987, 49: 729-734. PMID: 3612121, DOI: 10.1111/j.1471-4159.1987.tb00954.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAutoradiographyBrainCatheters, IndwellingCerebrovascular CirculationDeoxyglucoseDialysisGlucoseHippocampusMalePhosphorylationRatsRats, Inbred StrainsRegional Blood FlowConceptsLocal cerebral blood flowBlood flowDorsal hippocampusGlucose metabolismMicrodialysis fibersLocal cerebral glucose metabolismCerebral glucose metabolismCerebral blood flowRat dorsal hippocampusGlucose phosphorylationNear normalizationFocal disturbanceRecovery periodPronounced disturbancesHippocampusRatsImplantationMetabolismPhosphorylationRecovery timeGliosisSlight reductionLCMRglcLCMRglu