2022
Pregnenolone Reduces Stress-Induced Craving, Anxiety, and Autonomic Arousal in Individuals with Cocaine Use Disorder
Milivojevic V, Charron L, Fogelman N, Hermes G, Sinha R. Pregnenolone Reduces Stress-Induced Craving, Anxiety, and Autonomic Arousal in Individuals with Cocaine Use Disorder. Biomolecules 2022, 12: 1593. PMID: 36358943, PMCID: PMC9687893, DOI: 10.3390/biom12111593.Peer-Reviewed Original ResearchConceptsDiastolic blood pressureCocaine use disorderHeart ratePrecursor pregnenoloneUse disordersCocaine cravingCue-induced cocaine cravingCue-induced anxietyWeeks of treatmentCue-induced cravingAutonomic arousalChronic cocaine usePreg groupBlood pressureDay groupRelapse riskHigher cocainePregnenolone levelsCue-provoked cravingSeparate daysAutonomic responsesCocaine useTreatment-seeking individualsCravingSteroid systems
2011
Identification of a Sporozoite-Specific Antigen from Toxoplasma gondii
Hill D, Coss C, Dubey J, Wroblewski K, Sautter M, Hosten T, Muñoz-Zanzi C, Mui E, Withers S, Boyer K, Hermes G, Coyne J, Jagdis F, Burnett A, McLeod P, Morton H, Robinson D, McLeod R. Identification of a Sporozoite-Specific Antigen from Toxoplasma gondii. Journal Of Parasitology 2011, 97: 328-337. PMID: 21506817, PMCID: PMC3684278, DOI: 10.1645/ge-2782.1.Peer-Reviewed Original ResearchConceptsDetectable antibodiesToxoplasma gondiiEarly T. gondii infectionWestern blotT. gondii infectionRoute of infectionT. gondii sporozoitesAgents of infectionAcute stageChronic stageGondii infectionSerum antibodiesEpidemiological dataUninfected individualsInfection routeSerological assaysInfectionSporozoite-specific proteinsPrevious exposureAntibodiesReduction of riskAnimal infectionsPredominant routeDifference gel electrophoresisTandem mass spectroscopy
2005
Social isolation and the inflammatory response: sex differences in the enduring effects of a prior stressor
Hermes GL, Rosenthal L, Montag A, McClintock MK. Social isolation and the inflammatory response: sex differences in the enduring effects of a prior stressor. AJP Regulatory Integrative And Comparative Physiology 2005, 290: r273-r282. PMID: 16210419, DOI: 10.1152/ajpregu.00368.2005.Peer-Reviewed Original ResearchConceptsChronic social isolationInflammatory responseSocial isolationAnimal studiesPrior stressorsInnate inflammatory responseRobust inflammatory responseNumerous epidemiological studiesFemale Sprague-DawleyLong-term social isolationFirst animal studyAdverse psychological statesSex differencesNumerous disease processesInflammatory processSubcutaneous injectionSprague-DawleyLong-term effectsEpidemiological studiesDisease processShort-term effectsAcute stressSignificant sex differencesYoung adulthoodIsolated malesThe sectored foraging field: A novel design to quantify spatial strategies, learning, memory, and emotion
Hermes GL, Jacobs LF, McClintock MK. The sectored foraging field: A novel design to quantify spatial strategies, learning, memory, and emotion. Neurobiology Of Learning And Memory 2005, 84: 69-73. PMID: 15936684, DOI: 10.1016/j.nlm.2005.02.001.Peer-Reviewed Original ResearchConceptsNatural learning contextSame motor actionAnalysis of cognitionLearning strategiesSpatial navigation taskSpatial strategiesDifferent learning strategiesKinesthetic strategyCognitive performanceCue removalMotor actionsDifferent social ecologiesGroup contextMultiple learning strategiesLearning contextNavigation taskSocial ecologySocial environmentLocal cuesEmotionsCognitionGroup-housed ratsGroup-housed malesStressful environmentsAdulthood