2020
Predicting Antidepressant Citalopram Treatment Response via Changes in Brain Functional Connectivity After Acute Intravenous Challenge
Klöbl M, Gryglewski G, Rischka L, Godbersen GM, Unterholzner J, Reed MB, Michenthaler P, Vanicek T, Winkler-Pjrek E, Hahn A, Kasper S, Lanzenberger R. Predicting Antidepressant Citalopram Treatment Response via Changes in Brain Functional Connectivity After Acute Intravenous Challenge. Frontiers In Computational Neuroscience 2020, 14: 554186. PMID: 33123000, PMCID: PMC7573155, DOI: 10.3389/fncom.2020.554186.Peer-Reviewed Original ResearchBeck Depression InventoryFunctional connectivitySymptom improvementMajor depressionDepression InventoryLong-term antidepressant effectsSelective serotonin reuptake inhibitorsHamilton Depression Rating ScaleResting-state functional magnetic resonanceAcute pharmacological challengeSerotonin reuptake inhibitorsWhole-brain functional connectivityCross-over fashionDepression Rating ScaleMajor depressive disorderHigher lifetime prevalenceBrain functional connectivityDefault mode networkHeterogeneity of responseFunctional magnetic resonanceEscitalopram therapyAntidepressant effectsReuptake inhibitorsStandard medicationIntravenous challenge
2019
Predicting Ventral Striatal Activation During Reward Anticipation From Functional Connectivity at Rest
Mori A, Klöbl M, Okada G, Reed MB, Takamura M, Michenthaler P, Takagaki K, Handschuh PA, Yokoyama S, Murgas M, Ichikawa N, Gryglewski G, Shibasaki C, Spies M, Yoshino A, Hahn A, Okamoto Y, Lanzenberger R, Yamawaki S, Kasper S. Predicting Ventral Striatal Activation During Reward Anticipation From Functional Connectivity at Rest. Frontiers In Human Neuroscience 2019, 13: 289. PMID: 31507394, PMCID: PMC6718467, DOI: 10.3389/fnhum.2019.00289.Peer-Reviewed Original ResearchVentral striatumFunctional connectivityReward anticipationMonetary incentive delay taskResting-state functional connectivityIncentive delay taskVentral striatal activationFunctional magnetic resonanceTask-related activationDefault mode networkBrain functional networksMotivational salienceTask-free methodGain anticipationIndividual differencesDelay taskReward activationReward responsesStriatal activationMode networkFunctional networksRespective tasksTask implementationReward functionAnticipation