2023
Brain Networks and Adolescent Alcohol Use
Yip S, Lichenstein S, Liang Q, Chaarani B, Dager A, Pearlson G, Banaschewski T, Bokde A, Desrivières S, Flor H, Grigis A, Gowland P, Heinz A, Brühl R, Martinot J, Martinot M, Artiges E, Nees F, Orfanos D, Paus T, Poustka L, Hohmann S, Millenet S, Fröhner J, Smolka M, Vaidya N, Walter H, Whelan R, Schumann G, Garavan H. Brain Networks and Adolescent Alcohol Use. JAMA Psychiatry 2023, 80: 1131-1141. PMID: 37647053, PMCID: PMC10469292, DOI: 10.1001/jamapsychiatry.2023.2949.Peer-Reviewed Original ResearchConceptsAlcohol Use Disorders Identification TestAlcohol use riskAlcohol misuseUse riskAlcohol use disorderMale adolescentsDisorders Identification TestSingle-site studyIntervention effortsWhole-brain patternsMean ageAlcohol use dataLeading causeMagnetic resonance imaging dataMAIN OUTCOMEReward-related processesHigh riskSeparate cohortUse disordersAlcohol consumptionCurrent severityAdolescent neurodevelopmentAlcohol use behaviorsAlcohol useAUDIT scores
2010
Changes in Memory Function and Neuronal Activation Associated with Atorvastatin Therapy
Parker B, Polk D, Rabdiya V, Meda S, Anderson K, Hawkins K, Pearlson G, Thompson P. Changes in Memory Function and Neuronal Activation Associated with Atorvastatin Therapy. Pharmacotherapy The Journal Of Human Pharmacology And Drug Therapy 2010, 30: 625-625. DOI: 10.1592/phco.30.6.625.Peer-Reviewed Original ResearchFunctional magnetic resonance imagingCognitive complaintsCognitive test performanceMemory taskCognitive testsFMRI findingsFMRI patternsCognitive testingCognitive functionMemory functionCognitive symptomsMemory impairmentTest performanceNeuronal activationBrain functionPreliminary evidenceObjective measuresMemory lossPsychiatric problemsAtorvastatin therapyMajor head traumaFirst case reportDays of cessationCentral nervous systemAlcohol consumption
1991
Effects of Substance Abuse on Ventricular and Sulcal Measures Assessed by Computerised Tomography
Cascella N, Pearlson G, Wong D, Broussolle E, Nagoshi C, Margolin R, London E. Effects of Substance Abuse on Ventricular and Sulcal Measures Assessed by Computerised Tomography. The British Journal Of Psychiatry 1991, 159: 217-221. PMID: 1773237, DOI: 10.1192/bjp.159.2.217.Peer-Reviewed Original ResearchConceptsSubstance abuseSulcal measuresCocaine useSulcal widthWider third ventriclesEffect of ageBrain atrophyBrain ratioChronic useComputerised tomographyThird ventricleNormal controlsAlcohol consumptionBrain morphologyAlcohol usePolydrug abusersSignificant predictorsAgeVentricleSeverityTomographyPositive correlationAbusePossible effectsVentricular