2013
Direct assessment of hepatic mitochondrial oxidative and anaplerotic fluxes in humans using dynamic 13C magnetic resonance spectroscopy
Befroy DE, Perry RJ, Jain N, Dufour S, Cline GW, Trimmer JK, Brosnan J, Rothman DL, Petersen KF, Shulman GI. Direct assessment of hepatic mitochondrial oxidative and anaplerotic fluxes in humans using dynamic 13C magnetic resonance spectroscopy. Nature Medicine 2013, 20: 98-102. PMID: 24317120, PMCID: PMC3947269, DOI: 10.1038/nm.3415.Peer-Reviewed Original Research
1992
Cerebral Lactate Turnover after Electroshock: In vivo Measurements by 1H/13C Magnetic Resonance Spectroscopy
Petroff O, Novotny E, Avison M, Rothman D, Alger J, Ogino T, Shulman G, Prichard J. Cerebral Lactate Turnover after Electroshock: In vivo Measurements by 1H/13C Magnetic Resonance Spectroscopy. Cerebrovascular And Brain Metabolism Reviews 1992, 12: 1022-1029. PMID: 1400641, DOI: 10.1038/jcbfm.1992.139.Peer-Reviewed Original ResearchConceptsBlood lactateLactate poolNuclear magnetic resonance spectroscopyMetabolic stateBrain lactateBlood gasesBlood glucoseElevated lactateMagnetic resonance spectroscopyProlonged elevationRabbit brainPerchloric acid extractsPathological conditionsBrain activationBrainResonance spectroscopyLactate turnoverHigh resolution 1H NMRIntracellular pHElectroshockLactateHuman brainVivo 1HSignificant changesAcid extracts