2009
How to Identify the Asymptomatic High-Risk Patient?
Schuijf J, Achenbach S, Zoghbi W, Boersma E, Raggi P, Weber M, Nagel E, Narula J, Wackers F, Poldermans D, Bax J. How to Identify the Asymptomatic High-Risk Patient? Current Problems In Cardiology 2009, 34: 539-577. PMID: 19804855, DOI: 10.1016/j.cpcardiol.2009.07.001.Peer-Reviewed Original ResearchConceptsElevated riskAsymptomatic high-risk patientsCardiovascular disease eventsHigh-risk patientsCause of mortalityUse of biomarkersNoninvasive imaging modalityIntermediate riskAsymptomatic individualsCardiovascular diseaseHigh riskDisease eventsPreventive measuresImaging modalitiesSubstantial proportionMorbidityPatientsRisk assessmentAdditional strategiesRiskMortalityTraditional risk assessmentLarge proportionGreat benefitIndividuals
2008
Procedure Guideline for Myocardial Perfusion Imaging 3.3
Strauss H, Miller D, Wittry M, Cerqueira M, Garcia E, Iskandrian A, Schelbert H, Wackers F, Balon H, Lang O, Machac J. Procedure Guideline for Myocardial Perfusion Imaging 3.3. Journal Of Nuclear Medicine Technology 2008, 36: 155-161. PMID: 18703619, DOI: 10.2967/jnmt.108.056465.Peer-Reviewed Original Research
1999
Quantification of SPECT myocardial perfusion images: Methodology and validation of the Yale-CQ method
Liu Y, Sinusas A, DeMan P, Zaret B, Wackers F. Quantification of SPECT myocardial perfusion images: Methodology and validation of the Yale-CQ method. Journal Of Nuclear Cardiology 1999, 6: 190-203. PMID: 10327104, DOI: 10.1016/s1071-3581(99)90080-6.Peer-Reviewed Original Research
1993
Frequency and significance of right ventricular dysfunction during inferior wall left ventricular myocardial infarction treated with thrombolytic therapy (results from the Thrombolysis in Myocardial Infarction [TIMI] II trial)
Berger P, Ruocco N, Ryan T, Jacobs A, Zaret B, Wackers F, Frederick M, Faxon D, Group R. Frequency and significance of right ventricular dysfunction during inferior wall left ventricular myocardial infarction treated with thrombolytic therapy (results from the Thrombolysis in Myocardial Infarction [TIMI] II trial). The American Journal Of Cardiology 1993, 71: 1148-1152. PMID: 8097614, DOI: 10.1016/0002-9149(93)90637-r.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAngioplasty, Balloon, CoronaryCombined Modality TherapyConstriction, PathologicCoronary VesselsFemaleHeart DiseasesHeart VentriclesHumansMaleMiddle AgedMyocardial InfarctionRadionuclide VentriculographyThrombolytic TherapyTissue Plasminogen ActivatorVentricular Function, LeftVentricular Function, RightConceptsRV wall motion abnormalitiesRight ventricular dysfunctionRV dysfunctionVentricular myocardial infarctionWall motion abnormalitiesVentricular dysfunctionThrombolytic therapyRadionuclide ventriculographyMyocardial infarctionMotion abnormalitiesInferior wallLower mean left ventricular ejection fractionMean left ventricular ejection fractionLeft ventricular ejection fractionBaseline clinical characteristicsInfarct-related arteryMyocardial Infarction (TIMI) II trialVentricular ejection fractionEquilibrium radionuclide ventriculographyHospital complicationsMultivessel diseaseII trialClinical characteristicsHospital dischargeEjection fraction
1992
Comparison of thallium-201 and technetium-99m methoxyisobutyl isonitrile
Wackers F. Comparison of thallium-201 and technetium-99m methoxyisobutyl isonitrile. The American Journal Of Cardiology 1992, 70: e30-e34. PMID: 1442570, DOI: 10.1016/0002-9149(92)90036-x.Peer-Reviewed Original ResearchConceptsThallium-201Coronary artery diseaseComparative clinical trialsSimilar diagnostic yieldSingle photon emissionSymptomatic patientsArtery diseaseMethoxyisobutyl isonitrileNormalcy ratePrognostic significanceViable myocardiumClinical trialsDiagnostic yieldNumerous patientsMyocardial perfusionDiagnostic concordanceImaging protocolClinical applicationPatientsPrognostic proceduresGood specificityTechnetiumAgentsPerfusionMyocardium
1988
Peak filling rate normalized to mitral stroke volume: A new Doppler echocardiographic filling index validated by radionuclide angiographic techniques
Bowman L, Lee F, Jaffe C, Mattera J, Wackers F, Zaret B. Peak filling rate normalized to mitral stroke volume: A new Doppler echocardiographic filling index validated by radionuclide angiographic techniques. Journal Of The American College Of Cardiology 1988, 12: 937-943. PMID: 3417992, DOI: 10.1016/0735-1097(88)90458-5.Peer-Reviewed Original ResearchConceptsPeak filling rateMitral stroke volumeMean peak filling rateEnd-diastolic volumeStroke volumeFilling indexDoppler echocardiographyNormal patientsFilling velocityEarly peak filling velocityLate filling ratioEarly filling velocityDiastolic filling indexesLeft ventricular fillingTime-velocity integralPeak filling velocityRadionuclide angiographic techniquesFilling rateMitral inflowVentricular fillingMitral leafletEchocardiographic determinationMitral apparatusVelocity integralVentricular volume
1984
Pathoanatomic correlates of regional left ventricular wall motion assessed by equilibrium radionuclide angiocardiography: A postmortem correlation
Sinusas A, Hardin N, Clements J, Wackers F. Pathoanatomic correlates of regional left ventricular wall motion assessed by equilibrium radionuclide angiocardiography: A postmortem correlation. The American Journal Of Cardiology 1984, 54: 975-981. PMID: 6496360, DOI: 10.1016/s0002-9149(84)80128-9.Peer-Reviewed Original ResearchConceptsAbnormal regional wall motionRegional wall motionPostmortem findingsPathoanatomic correlatesEquilibrium radionuclideLeft bundle branch blockNormal regional wall motionGross myocardial lesionsLeft ventricular wall motionBundle branch blockLeft ventricular segmentsRegional left ventricular wall motionVentricular wall motionFalse-negative segmentsCoronary arterySevere stenosisMyocardial infarctionNontransmural infarctionBranch blockVentricular segmentsWall motionMyocardial lesionsPatientsPredictive valueAbnormal segments
1983
Anatomic and prognostic significance of new T-wave inversion in unstable angina
Haines D, Raabe D, Gundel W, Wackers F. Anatomic and prognostic significance of new T-wave inversion in unstable angina. The American Journal Of Cardiology 1983, 52: 14-18. PMID: 6602539, DOI: 10.1016/0002-9149(83)90061-9.Peer-Reviewed Original ResearchConceptsT-wave inversionNew T-wave inversionAnterior T-wave inversionSignificant right coronary artery diseaseRight coronary artery diseaseLeft anterior descending (LAD) arteryPositive predictive value 86Anterior descending (LAD) arteryCoronary artery diseaseSignificant LAD stenosisCoronary care unitInferior T-wave inversionsUnstable anginaArtery diseaseConsecutive patientsCoronary angiographyLAD stenosisCare unitInferior leadsSpecificity 89PatientsDiameter reductionAnginaHospitalizationStenosis
1981
Exercise left ventricular performance in patients with chest pain, ischemic-appearing exercise electrocardiograms, and angiographically normal coronary arteries.
Berger HJ, Sands MJ, Davies RA, Wackers FJ, Alexander J, Lachman AS, Williams BW, Zaret BL. Exercise left ventricular performance in patients with chest pain, ischemic-appearing exercise electrocardiograms, and angiographically normal coronary arteries. Annals Of Internal Medicine 1981, 94: 186-91. PMID: 7469209, DOI: 10.7326/0003-4819-94-2-186.Peer-Reviewed Original ResearchConceptsNormal coronary arteriesLeft ventricular performanceChest painVentricular performanceCoronary arteryExercise electrocardiogramAbnormal ejection fraction responseMaximal upright bicycle exerciseCoronary arterial spasmUpright bicycle exerciseEjection fraction responseFirst-pass radionuclide angiocardiographyThallium-201 imagingErgonovine testingVentricular dysfunctionArterial spasmBicycle exerciseErgonovine provocationAdditional patientsTreadmill exercisePerfusion defectsRadionuclide angiocardiographyRegional dysfunctionPatientsFraction response
1980
Radionuclide Evaluation of Patients in the Coronary Care Unit
Wackers F. Radionuclide Evaluation of Patients in the Coronary Care Unit. Advances In Cardiology 1980, 27: 105-113. PMID: 7446281, DOI: 10.1159/000383980.Peer-Reviewed Original Research
1976
Coronary artery disease in patients dying from cardiogenic shock or congestive heart failure in the setting of acute myocardial infarction.
Wackers F, Lie K, Becker A, Durrer D, Wellens H. Coronary artery disease in patients dying from cardiogenic shock or congestive heart failure in the setting of acute myocardial infarction. Heart 1976, 38: 906. PMID: 971375, PMCID: PMC483104, DOI: 10.1136/hrt.38.9.906.Peer-Reviewed Original ResearchConceptsCongestive heart failureAcute myocardial infarctionHeart failureCardiogenic shockCoronary arteryMyocardial infarctionSevere diseaseFatal congestive heart failureRefractory congestive heart failurePump failureThree-vessel diseaseCoronary bypass surgeryRight coronary arteryCoronary artery diseaseLeft circumflex arteryCent narrowingBypass surgeryArtery diseaseLeft anteriorCircumflex arteryPathological findingsSevere narrowingEqual incidenceAnatomical findingsPatients