1990
Quantitative analysis of planar technetium-99m-sestamibi myocardial perfusion images using modified background subtraction.
Koster K, Wackers F, Mattera J, Fetterman R. Quantitative analysis of planar technetium-99m-sestamibi myocardial perfusion images using modified background subtraction. Journal Of Nuclear Medicine 1990, 31: 1400-8. PMID: 2143529.Peer-Reviewed Original Research
1989
Variables predictive of good functional outcome following thrombolytic therapy in the Thrombolysis in Myocardial Infarction phase II (TIMI II) pilot study
Rogers W, Bourge R, Papapietro S, Wackers F, Zaret B, Forman S, Dodge H, Robertson T, Passamani E, Braunwald E, Investigators F. Variables predictive of good functional outcome following thrombolytic therapy in the Thrombolysis in Myocardial Infarction phase II (TIMI II) pilot study. The American Journal Of Cardiology 1989, 63: 503-512. PMID: 2521976, DOI: 10.1016/0002-9149(89)90889-8.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionGood functional outcomeAngioplasty groupEjection fractionPeak exerciseHospital dischargeFunctional outcomePilot studyMyocardial Infarction Phase II (TIMI II) studyIntravenous recombinant tissue plasminogen activatorLeft ventricular ejection fractionPhase II pilot studyRecombinant tissue plasminogen activatorPhase II studyGood ventricular functionHours of onsetPercutaneous transluminal angioplastyRt-PA infusionVentricular ejection fractionObservational pilot studyST-segment elevationEquilibrium radionuclide ventriculographyGated equilibrium radionuclide ventriculographyAbsence of arrhythmiasTissue plasminogen activatorTechnetium-99m hexakis 2-methoxyisobutyl isonitrile: human biodistribution, dosimetry, safety, and preliminary comparison to thallium-201 for myocardial perfusion imaging.
Wackers F, Berman D, Maddahi J, Watson D, Beller G, Strauss H, Boucher C, Picard M, Holman B, Fridrich R. Technetium-99m hexakis 2-methoxyisobutyl isonitrile: human biodistribution, dosimetry, safety, and preliminary comparison to thallium-201 for myocardial perfusion imaging. Journal Of Nuclear Medicine 1989, 30: 301-11. PMID: 2525610.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseArtery diseaseMulticenter phase II clinical trialSignificant coronary artery diseasePhase II clinical trialMulticenter phase IStress imagesMyocardial perfusion imagingNew myocardial imaging agentHuman biodistributionClinical efficacyClinical trialsMyocardial analysisStress imagingMyocardial imaging agentMyocardial uptakeMyocardial segmentsNormal volunteersThallium-201Myocardial imagingPerfusion imagingPatientsPhase IExact concordanceMyocardial images