2009
Detection of coronary artery disease with perfusion stress echocardiography using a novel ultrasound imaging agent: two Phase 3 international trials in comparison with radionuclide perfusion imaging
Senior R, Monaghan M, Main M, Zamorano J, Tiemann K, Agati L, Weissman N, Klein A, Marwick T, Ahmad M, DeMaria A, Zabalgoitia M, Becher H, Kaul S, Udelson J, Wackers F, Walovitch R, Picard M. Detection of coronary artery disease with perfusion stress echocardiography using a novel ultrasound imaging agent: two Phase 3 international trials in comparison with radionuclide perfusion imaging. European Heart Journal - Cardiovascular Imaging 2009, 10: 26-35. PMID: 19131498, DOI: 10.1093/ejechocard/jen321.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overArea Under CurveContrast MediaCoronary Artery DiseaseDipyridamoleEchocardiography, StressFemaleFluorocarbonsGated Blood-Pool ImagingHumansImage EnhancementImage Interpretation, Computer-AssistedInternational CooperationMaleMiddle AgedObserver VariationROC CurveSensitivity and SpecificityStatistics, NonparametricTomography, Emission-Computed, Single-PhotonYoung AdultConceptsChest pain patientsPain patientsStress echocardiographyPerfusion imagingNon-inferior sensitivityPhase 3 trialCoronary artery diseaseCoronary artery disease detectionQuantitative coronary angiographyNon-inferiority analysisRadionuclide perfusion imagingSingle photon emissionAdverse eventsArtery diseaseCoronary angiographyBlinded cardiologistsClinical reviewDipyridamole stressMyocardial perfusionSPECT perfusionInternational trialRAMP 1Diagnostic performanceSPECTCharacteristic curve
2008
Utility of Cardiac Biomarkers in Predicting Infarct Size, Left Ventricular Function, and Clinical Outcome After Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction
Chia S, Senatore F, Raffel O, Lee H, Wackers F, Jang I. Utility of Cardiac Biomarkers in Predicting Infarct Size, Left Ventricular Function, and Clinical Outcome After Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction. JACC Cardiovascular Interventions 2008, 1: 415-423. PMID: 19463339, DOI: 10.1016/j.jcin.2008.04.010.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryBenzenesulfonatesBiomarkersCardiovascular AgentsCoronary AngiographyCreatine Kinase, MB FormDisease-Free SurvivalFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMyocardial InfarctionMyocardiumPiperazinesPredictive Value of TestsProportional Hazards ModelsProspective StudiesRisk AssessmentStroke VolumeTime FactorsTomography, Emission-Computed, Single-PhotonTreatment OutcomeTroponin ITroponin TUnited StatesVentricular Function, LeftConceptsST-segment elevation myocardial infarctionPrimary percutaneous coronary interventionPrimary PCIElevation myocardial infarctionPercutaneous coronary interventionInfarct sizeClinical outcomesMyocardial infarctionCardiac biomarkersCoronary interventionCreatine kinaseCK-MBLarge ST-segment elevation myocardial infarctionTroponin TIntracellular calcium modulatorsLarger infarct sizeVentricular ejection fractionCardiac biomarker levelsLeft ventricular functionComposite clinical eventsTime-concentration curveEVOLVE trialLower LVEFAdverse eventsEjection fraction