2024
FACTFINDERS FOR PATIENT SAFETY: Minimizing risks with cervical epidural injections
Holder E, Lee H, Raghunandan A, Marshall B, Michalik A, Nguyen M, Saffarian M, Schneider B, Smith C, Tiegs-Heiden C, Zheng P, Patel J, Levi D, Committee I. FACTFINDERS FOR PATIENT SAFETY: Minimizing risks with cervical epidural injections. Interventional Pain Medicine 2024, 3: 100430. PMID: 39502902, PMCID: PMC11536293, DOI: 10.1016/j.inpm.2024.100430.Peer-Reviewed Original ResearchEpidural steroid injectionsCervical transforaminal epidural steroid injectionsTransforaminal epidural steroid injectionCervical epidural injectionsSpinal cord injurySteroid injectionContralateral obliqueDural punctureEpidural hematomaCervical interlaminar epidural steroid injectionCord injuryEpidural injectionEpidural spaceCatastrophic neurologic injuryLoss of resistanceInterlaminar epidural steroid injectionsComplication of dural punctureComplication of spinal cord injuryNeedle placementCase reports of patientsReview of cross-sectional imagingSevere systemic complicationsInadvertent dural puncturePatient safetyReports of patientsFACTFINDERS for PATIENT SAFETY: Preventing procedure-related complications: Epidural lipomatosis and postpartum steroid exposure
D'Souza R, Zheng P, Christolias G, Holder E, Lee H, Miller D, Raghunandan A, Smith C, Patel J, Committee I. FACTFINDERS for PATIENT SAFETY: Preventing procedure-related complications: Epidural lipomatosis and postpartum steroid exposure. Interventional Pain Medicine 2024, 3: 100408. PMID: 39238584, PMCID: PMC11372935, DOI: 10.1016/j.inpm.2024.100408.Peer-Reviewed Original ResearchEpidural steroid injectionsSpinal epidural lipomatosisProcedure-related complicationsSpinal stenosisSteroid injectionHypothalamic-pituitary-adrenalEpidural lipomatosisSteroid exposureDuration of breastfeedingLow-level evidenceResponse to steroid administrationPatient safetySteroid administrationNeurological compromiseInsufficient evidencePostpartumBreast milkLipomatosisStenosisSpinalInfant exposureSteroidsComplicationsInjectionBreastfeeding
2023
Risk of SARS‐CoV‐2 following joint and epidural corticosteroid injections: A retrospective study
Raju R, Holder E, Dundas M, Liang J, Donham R. Risk of SARS‐CoV‐2 following joint and epidural corticosteroid injections: A retrospective study. Pain Practice 2023, 24: 472-482. PMID: 37994676, DOI: 10.1111/papr.13321.Peer-Reviewed Original ResearchPCR positivity ratesCharlson Comorbidity IndexInjection groupPositivity rateCS injectionsControl groupCorticosteroid injectionSevere comorbiditiesPolymerase chain reaction positivitySARS-CoV-2 PCREpidural corticosteroid injectionsRetrospective chart reviewTertiary care centerCohort of patientsSignificant disease burdenCoronavirus disease 2019 (COVID-19) pandemicSignificant higher rateSARS-CoV-2Disease 2019 pandemicMultivariate regression analysisComorbidity indexPatients 18Chart reviewRetrospective studyImmunosuppressive effectsFactFinders for patient safety: Preventing local anesthetic-related complications: Local anesthetic chondrotoxicity and stellate ganglion blocks
Saffarian M, Holder E, Mattie R, Smith C, Christolias G, Patel J, McCormick Z, Committee S. FactFinders for patient safety: Preventing local anesthetic-related complications: Local anesthetic chondrotoxicity and stellate ganglion blocks. Interventional Pain Medicine 2023, 2: 100282. PMID: 39239227, PMCID: PMC11372873, DOI: 10.1016/j.inpm.2023.100282.Peer-Reviewed Original ResearchAnesthetic-related complicationsStellate ganglion blockLocal anestheticsGanglion blockAdverse outcomesIntraarticular injectionUltrasound guidanceCurrent evidenceFluoroscopic techniquePatient safetyChondrotoxic effectsVascular structuresEquivalent volumeAnestheticsSoft tissue visualizationComplicationsChondrotoxicityTissue visualizationRiskEvidenceBupivacaineRopivacaineChondrotoxicFactFinders for patient safety: Understanding potential procedure-related complications: RFN/multifidus atrophy, intradiscal biologics, and facet cyst rupture
Nguyen M, Saffarian M, Smith C, Holder E, Lee H, Marshall B, Mattie R, Patel J, Schneider B, McCormick Z, Committee S. FactFinders for patient safety: Understanding potential procedure-related complications: RFN/multifidus atrophy, intradiscal biologics, and facet cyst rupture. Interventional Pain Medicine 2023, 2: 100248. PMID: 39238672, PMCID: PMC11372888, DOI: 10.1016/j.inpm.2023.100248.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsLumbar medial branch radiofrequency neurotomyPotential procedure-related complicationsProcedure-related complicationsMultifidus atrophyCyst ruptureHigh-quality prospective studiesMedial branch radiofrequency neurotomyNerve root compressionRisk of complicationsReports of complicationsCross-sectional imagingRadiofrequency neurotomyRoot compressionProspective studyIntradiscal injectionBiologic interventionsClinical relevanceComplicationsLarger sample sizeAtrophyNatural historyPatient safetyAvailable evidenceComparison groupBiologicsDoes Lumbar Medial Branch Radiofrequency Neurotomy Cause Multifidus Atrophy? Spine Intervention Society Factfinders for Patient Safety
Nguyen M, Holder EK, Marshall BJ, Smith CC, Patel J, McCormick ZL. Does Lumbar Medial Branch Radiofrequency Neurotomy Cause Multifidus Atrophy? Spine Intervention Society Factfinders for Patient Safety. February 2023Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsEpidural Injections for Radicular Pain Due to Spinal Stenosis Caused by Lipomatosis. Spine Intervention Society Factfinders for Patient Safety
D'Souza RS, Christiolas G, Holder EK, Lee H, Smith C, Patel J. Epidural Steroid Injections for Radicular Pain Due to Spinal Stenosis caused by Lipomatosis. Spine Intervention Society Factfinders for Patient Safety.June 2023Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2022
Changes in the Utilization of Lumbosacral Epidural Injections Between 2010 and 2019
Ratnasamy PP, Gouzoulis MJ, Kammien AJ, Holder EK, Grauer JN. Changes in the Utilization of Lumbosacral Epidural Injections Between 2010 and 2019. Spine 2022, 47: 1669-1674. PMID: 36281568, PMCID: PMC9643603, DOI: 10.1097/brs.0000000000004467.Peer-Reviewed Original ResearchConceptsElixhauser Comorbidity IndexEpidural injectionTransforaminal injectionsSpinal epidural injectionDescriptive epidemiologic studyLumbosacral epidural injectionNumber of injectionsCurrent Procedural Terminology codingCaudal injectionComorbidity indexPatient agePatient characteristicsPearlDiver databaseLumbar pathologyTerms of specialtyInsurance authorizationPractice patternsService utilizationAverage patientEpidemiologic studiesMedicaid coveragePatientsTransforaminalMedicare coverageUtilization trendsAtypical knee pain.
Berger GK, Milligan K, Holder EK, Schwab JM, Rubin LE. Atypical knee pain. The Journal Of Family Practice 2022, 71: 181-184. PMID: 35730713, DOI: 10.12788/jfp.0404.Peer-Reviewed Case Reports and Technical NotesIs there an association between lumbosacral epidural lipomatosis and lumbosacral epidural steroid injections? A comprehensive narrative literature review
Holder EK, Raju R, Dundas MA, Husu EN, McCormick ZL. Is there an association between lumbosacral epidural lipomatosis and lumbosacral epidural steroid injections? A comprehensive narrative literature review. North American Spine Society Journal (NASSJ) 2022, 9: 100101. PMID: 35243452, PMCID: PMC8857075, DOI: 10.1016/j.xnsj.2022.100101.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsLumbosacral epidural lipomatosisLumbosacral epidural steroid injectionsSpinal epidural lipomatosisEpidural steroid injectionsEpidural lipomatosisRadicular painCorticosteroid exposureSteroid injectionSystemic steroid exposureHigh-quality studiesPatients' clinical dataDevelopment/progressionIndependent causal relationshipCurrent management recommendationsSteroid exposureTreatment optionsRisk factorsClinical dataPainLipomatosisNarrative literature reviewNotable associationGoogle ScholarPotential painComprehensive narrative literature reviewChondrotoxicity: Which Local Anesthetics are Safest for Intraarticular Injections? Spine Intervention Society Factfinders for Patient Safety
Holder E.K., Christolias G, Saffarian M, Patel J, McCormick ZL. Chondrotoxicity: Which Local Anesthetics are Safest for Intraarticular Injection? Spine Intervention Society Factfinders for Patient Safety. Interventional Pain Medicine. April 2022.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2020
Clinical and Anatomical Considerations for Management of a Complete Tear of the Distal Rectus Femoris Myotendinous Junction
Holder EK, Rose A, Haims A. Clinical and Anatomical Considerations for Management of a Complete Tear of the Distal Rectus Femoris Myotendinous Junction. American Journal Of Physical Medicine & Rehabilitation 2020, 100: e69-e72. PMID: 32769377, DOI: 10.1097/phm.0000000000001559.Peer-Reviewed Case Reports and Technical NotesConceptsCase reportMuscle injuryDistal myotendinous junctionQuadriceps muscle injuriesRectus femoris injuriesKnee extensor mechanismMyotendinous junctionFemoris injuriesRadiologic presentationSurgical managementComplete tearsExtensor mechanismAnatomical considerationsClinical considerationsInjuryPresentationManagement considerationsSparse literatureReportDiagnosisTears
2018
Chapter 7: Arthritis and Joint Replacement
Moley P, Holder EK. Arthritis and Joint Replacement. Geriatric Rehabilitation. 1st Edition edited by Cifu, David, Lew Henry, Oh-Park Mooyeon. Elsevier Publishing Company.Chapters
2017
Abdominal wall Type-I complex regional pain syndrome treated effectively with peripheral nerve field stimulation: a case report
Zhou L, Chou H, Holder E. Abdominal wall Type-I complex regional pain syndrome treated effectively with peripheral nerve field stimulation: a case report. Journal Of Surgical Case Reports 2017, 2017: rjw222. PMID: 28044002, PMCID: PMC5204132, DOI: 10.1093/jscr/rjw222.Peer-Reviewed Case Reports and Technical NotesComplex regional pain syndromeSpinal cord stimulationPeripheral nerve field stimulationThoracic spinal cord stimulationRegional pain syndromePain reliefPain syndromeField stimulationChronic abdominal wall painSubstantial pain reliefAbdominal wall painRare medical conditionPeriumbilical painUnderlining pathologyConservative therapyAbdominal surgeryCord stimulationCase reportSignificant reliefMedical conditionsPainStimulationSyndromeReliefPNFChapter 10: Functional Therapeutic and Core Strengthening.
Malanga, G.A., Aydin, S.M., Holder, E.K., Petrin, Z. (2017). Functional Therapeutic and Core Strengthening. In: Seidenberg MD, FAAFP, FACSM, RMSK, P., Bowen MD, FAAPMR, CAQSM, RMSK, CSCS, J., King MD, D. (eds) The Hip and Pelvis in Sports Medicine and Primary Care. Springer, Cham. https://doi.org/10.1007/978-3-319-42788-1_10Chapters
2015
Acute Disseminated Encephalomyelitis in an Adult: An Uncommon Case of Paroxysmal Sympathetic Hyperactivity
Holder EK, McCall JC, Feeko KJ. Acute Disseminated Encephalomyelitis in an Adult: An Uncommon Case of Paroxysmal Sympathetic Hyperactivity. PM&R 2015, 7: 781-784. PMID: 25724850, DOI: 10.1016/j.pmrj.2015.02.006.Peer-Reviewed Case Reports and Technical NotesConceptsAcute disseminated encephalomyelitisParoxysmal sympathetic hyperactivitySympathetic hyperactivityDisseminated encephalomyelitisCentral nervous systemList of diagnosesAutonomic dysreflexiaProgressive autoimmuneFulminant casesHypertensive emergenciesAdult patientsMultiple sclerosisPediatric casesCase reportUncommon caseNervous systemHyperactivityEncephalomyelitisDysreflexiaAutoimmuneAcuteSclerosisPatientsRecurrenceImmunization
2014
Radiologic Presentation of a Type 1 Dens Fracture
Holder EK, Husu EN, Flanders AE. Radiologic Presentation of a Type 1 Dens Fracture. PM&R 2014, 7: 547-549. PMID: 25511689, DOI: 10.1016/j.pmrj.2014.11.012.Peer-Reviewed Case Reports and Technical NotesPathophysiology and Treatment of Discogenic and Radicular Lower Back Pain.
Zhou L, Holder EK, Leahy HP. Pathophysiology and Treatment of Discogenic and Radicular Lower Back Pain. Int J Phys Med Rehabil 2:e107. doi: 10.4172/2329-9096.1000e107Commentaries, Editorials and Letters