2005
The origin and evolution of human pathogens
Groisman EA, Casadesús J. The origin and evolution of human pathogens. Molecular Microbiology 2005, 56: 1-7. PMID: 15773974, DOI: 10.1111/j.1365-2958.2005.04564.x.Peer-Reviewed Original ResearchConceptsCreation of genesNon-host environmentsHuman pathogensRelated bacterial speciesCertain pathogensORFan genesHomologous genesCell surface modificationExpression of productsHousekeeping functionsRelated membersHost rangeColonization processTissue specificityPathogenicity islandSequence databasesCertain lociBacterial speciesGenesCell surfaceDisparate regulationGenetic originBacterial pathogensNew functionsGene variation
2002
Pathogenicity Islands of Shigella
Ingersoll M, Groisman EA, Zychlinsky A. Pathogenicity Islands of Shigella. Current Topics In Microbiology And Immunology 2002, 264: 49-65. PMID: 12014181, DOI: 10.1007/978-3-662-09217-0_4.Peer-Reviewed Original ResearchPathogenicity Islands of Shigella
Ingersoll M, Groisman E, Zychlinsky A. Pathogenicity Islands of Shigella. Current Topics In Microbiology And Immunology 2002, 264/2: 49-65. DOI: 10.1007/978-3-642-56031-6_4.Peer-Reviewed Original ResearchIntestinal epithelial barrierResident tissue macrophagesAbdominal crampsLymphoid folliclesMild diarrheaSevere formTissue macrophagesEpithelial barrierEnteric pathogensShigella speciesBacillary dysenteryM cellsDisease rangeCausative agentShigellaeHost cell cytoplasmHuman pathogensShigellaPathogenicity islandDisease symptoms