Denny Sakkas, PhD

2026

• Multicentre randomised comparative effectiveness trial of cleavage-stage versus blastocyst-stage embryo transfer in patients with few embryos (PRECISE): implementation of a study protocol in reproductive medicine

  Neuhausser W, Vaughan D, Sakkas D, Penzias A, Anchan R, Hornstein M, Reeder H, Barnhart K, Stewart E, Cedars M, Halicigil C, Taylor H, Beck M, Hacker M, Marsh E, Gracia C, Rosenwaks Z, Williams Z, Rabideau D, Trial S, Trial C, Trial P, Trial S, Trial D, Trial C, Trial S, Barnhart K, Neuhausser W, Stewart E, Marsh E, Halicigil C, Hornstein M, Penzias A, Williams Z, Stewart J, Gracia C, Rabideau D, Trial C, Neuhausser W, Rabideau D, Barnhart K, Stewart E, Hornstein M, Penzias A, Sakkas D, Halicigil C, Trial P, Hornstein M, Neuhausser W, Rabideau D, Barnhart K, Penzias A, Sakkas D, Ainsworth A, Trial S, Collura B, Fankhauser D, Domar A, Patel J, Freeman N, Bortoletto P, Petrozza J, Ginsburg E, Robbins J, Penzias A, Dlugi A, Psaros C, Trial D, Baker V, Schust D, McCaffrey C, Farland L, Fan L, Cody J, Rebar B, Trial C, Valbrun T, Neuhausser W, Gracia C, Larson E, Trial P, Neuhausser W, Barnhart K, Rinaudo P, Halicigil C, Reeder H, Hornstein M, Sakkas D. Multicentre randomised comparative effectiveness trial of cleavage-stage versus blastocyst-stage embryo transfer in patients with few embryos (PRECISE): implementation of a study protocol in reproductive medicine. BMJ Open 2026, 16: e107903. PMID: 42552004, PMCID: PMC13479505, DOI: 10.1136/bmjopen-2025-107903.

  Peer-Reviewed Original Research

  MeSH Keywords

• Recurrent implantation failure: a committee opinion

  Medicine P, Gracia C, Amato P, Flyckt R, Ginsburg E, Brannigan R, Sakkas D, Senapati S, Smith R, Plowden T, Brooks M, Goldstein J, Hansen K, Hill M, Jindal S, Kalra S, Jain T, Pier B, Robins J, Shannon C, Steiner A, Tanrikut C, Yauger B. Recurrent implantation failure: a committee opinion. Fertility And Sterility 2026, 126: 277-293. PMID: 42538063, DOI: 10.1016/j.fertnstert.2026.03.026.

  Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements

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  MeSH Keywords

• Metabolic imaging for gamete and embryo assessment through advanced microscopy technologies: a novel avenue for artificial intelligence?

  Horta F, Sakkas D, Handley S, Xiong Y, Mihalas B, Deans R, Hart R, Gilchrist R, Goldys E. Metabolic imaging for gamete and embryo assessment through advanced microscopy technologies: a novel avenue for artificial intelligence? Human Reproduction 2026, 41: 1470-1481. PMID: 42449562, PMCID: PMC13550671, DOI: 10.1093/humrep/deag114.

  Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements

  MeSH Keywords

• Position statement on Rho(d) immune globulin Administration in the first trimester

  Medicine P, Gracia C, Yauger B, Sakkas D, Trolice M, Smith R, Flyckt R, Jain T, Plowden T, Senapati S, Pier B, Kalra S, Sparks A, Robins J, Shannon C. Position statement on Rho(d) immune globulin Administration in the first trimester. Fertility And Sterility 2026, 126: 492-493. PMID: 42420053, DOI: 10.1016/j.fertnstert.2026.06.007.

  Peer-Reviewed Original Research

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• Diagnosis and treatment of luteal phase deficiency: a Committee Opinion

  Endocrinology and Infertility P, Gracia C, Jain T, Kalra S, Pier B, Sakkas D, Yauger B, Flyckt R, Plowden T, Smith R, Senapati S, Brannigan R, Sparks A, Robins J, Shannon C, Goldstein J, Brooks M. Diagnosis and treatment of luteal phase deficiency: a Committee Opinion. Fertility And Sterility 2026 PMID: 42414147, DOI: 10.1016/j.fertnstert.2026.06.014.

  Peer-Reviewed Original Research

  Citations

• Fertility care and family building for LGBTQ+ individuals: a committee opinion

  Medicine P, Gracia C, Flyckt R, Hansen K, Hill M, Jain T, Kalra S, Pier B, Sakkas D, Steiner A, Tanrikut C, Yauger B, Plowden T, Smith R, Trolice M, Senapati S, Brannigan R, Amato P, Sparks A, Robins J, Shannon C, Brooks M. Fertility care and family building for LGBTQ+ individuals: a committee opinion. Fertility And Sterility 2026, 126: 312-323. PMID: 42264981, DOI: 10.1016/j.fertnstert.2026.05.005.

  Peer-Reviewed Original Research

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• Clinical embryology in the United States: current landscape and considerations for professional development and standardization

  Gvakharia M, Sakkas D, Ezzati M, Ribeiro S, Sparks A, Go K, Bartolucci A, Celia G, Nichols-Burns S, Ali S, Baker M, Swain J, VerMilyea M, Albertini D, Jellerette-Nolan T, Jindal S, Gvakharia M, Sakkas D, Bartolucci A, Ali S, Baker M, Swain J, VerMilyea M, Albertini D, Jindal S. Clinical embryology in the United States: current landscape and considerations for professional development and standardization. Fertility And Sterility 2026, 126: 475-480. PMID: 42176841, DOI: 10.1016/j.fertnstert.2026.05.159.

  Peer-Reviewed Original Research

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• Intracytoplasmic sperm injection for nonmale factor indications: a Committee opinion

  Medicine P, Gracia C, Flyckt R, Hansen K, Jain T, Kalra S, Pier B, Sakkas D, Yauger B, Plowden T, Smith R, Trolice M, Senapati S, Brannigan R, Sparks A, Robins J, Shannon C, Goldstein J, Brooks M, Technology P. Intracytoplasmic sperm injection for nonmale factor indications: a Committee opinion. Fertility And Sterility 2026, 126: 49-56. PMID: 42091403, DOI: 10.1016/j.fertnstert.2026.03.032.

  Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements

  Citations

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  MeSH Keywords

• Witnessing and protocol deviations in the in vitro fertilization and andrology laboratory: a committee opinion

  Medicine P, Gracia C, Flyckt R, Sakkas D, Hansen K, Jain T, Kalra S, Pier B, Yauger B, Plowden T, Smith R, Trolice M, Senapati S, Brannigan R, Sparks A, Robins J, Shannon C, Goldstein J, Brooks M, Biologists and Technologists P. Witnessing and protocol deviations in the in vitro fertilization and andrology laboratory: a committee opinion. Fertility And Sterility 2026, 126: 38-48. PMID: 42067437, DOI: 10.1016/j.fertnstert.2026.03.014.

  Peer-Reviewed Original Research

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• Can Cell-Free DNA in the Culture Medium Predict the Chromosomal Constitution of Preimplantation Embryos? Final Results from a Multicenter Study with 2539 Blastocysts

  Navarro-Sánchez L, Sakkas D, Frantz N, de la Fuente Lucena E, Venier W, Soscia D, Barroso G, Bisioli C, DiMattina M, Teke B, Escudero L, Rubio C. Can Cell-Free DNA in the Culture Medium Predict the Chromosomal Constitution of Preimplantation Embryos? Final Results from a Multicenter Study with 2539 Blastocysts. Genes 2026, 17: 416. PMID: 42074534, PMCID: PMC13116962, DOI: 10.3390/genes17040416.

  Peer-Reviewed Original Research

  MeSH Keywords