2008
Prevalence and Correlates of Previous Hepatitis B Vaccination and Infection Among Young Drug-users In New York City
Amesty S, Ompad D, Galea S, Fuller C, Wu Y, Koblin B, Vlahov D. Prevalence and Correlates of Previous Hepatitis B Vaccination and Infection Among Young Drug-users In New York City. Journal Of Community Health 2008, 33: 139-148. PMID: 18185987, DOI: 10.1007/s10900-007-9082-4.Peer-Reviewed Original ResearchConceptsEvidence of infectionHBV vaccinationPrevious vaccinationSerological evidenceHepatitis B vaccination coveragePrevious hepatitis B vaccinationPrevious HBV infectionPrevious HBV vaccinationHepatitis B vaccinationHepatitis B vaccineHigh-risk groupYears of ageCommunity-based sampleB vaccinationHBV infectionB vaccineVaccination statusVaccination coverageRisk groupsHigh school educationVaccinationSusceptible individualsDrug usersInfection rateBivariate analysis
2007
Early immunologic and virologic responses to highly active antiretroviral therapy and subsequent disease progression among HIV-infected injection drug users
Mehta S, Lucas G, Astemborski J, Kirk G, Vlahov D, Galai N. Early immunologic and virologic responses to highly active antiretroviral therapy and subsequent disease progression among HIV-infected injection drug users. AIDS Care 2007, 19: 637-645. PMID: 17505924, DOI: 10.1080/09540120701235644.Peer-Reviewed Original ResearchConceptsInjection drug usersActive antiretroviral therapyRisk of progressionVirologic responseTreatment interruptionImmunologic responseAntiretroviral therapyCommunity-based injection drug usersDrug usersMultiple Cox regression analysisRecent outpatient visitYears of HAARTCox regression analysisInjection drug useNew AIDS diagnosesSubsequent disease progressionEarly responseHAART initiationHAART initiatorsHIV careOutpatient visitsCox regressionPrognostic valueAIDS diagnosisPoor response
2005
Haplotype analysis of the SDF-1 (CXCL12) gene in a longitudinal HIV-1/AIDS cohort study
Modi W, Scott K, Goedert J, Vlahov D, Buchbinder S, Detels R, Donfield S, O'Brien S, Winkler C. Haplotype analysis of the SDF-1 (CXCL12) gene in a longitudinal HIV-1/AIDS cohort study. Genes & Immunity 2005, 6: 691-698. PMID: 16177829, DOI: 10.1038/sj.gene.6364258.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeAdolescentAdultAllelesBlack or African AmericanChemokine CXCL12Chemokines, CXCChildCohort StudiesDisease ProgressionFemaleGene FrequencyHaplotypesHIV InfectionsHIV-1HumansLongitudinal StudiesMaleOdds RatioPolymorphism, Single NucleotideRisk FactorsSurvival AnalysisUnited StatesWhite PeopleConceptsSDF-1 geneCohort studySingle nucleotide polymorphismsAfrican AmericansOnly natural ligandSingle disease outcomesX4 HIV-1HIV-1 infectionAIDS Cohort StudyRisk of infectionMACS cohortDisease outcomeHIV-1Epidemiological studiesSDF-1Significant associationChemokine genesInfectionRs1801157Natural ligandProgressionHaplotype analysisCommon haplotypeCXCR4CohortSexual Risk Behavior Among Injection Drug Users Before Widespread Availability of Highly Active Antiretroviral Therapy
Rusch M, Farzadegan H, Tarwater P, Safaeian M, Vlahov D, Strathdee S. Sexual Risk Behavior Among Injection Drug Users Before Widespread Availability of Highly Active Antiretroviral Therapy. AIDS And Behavior 2005, 9: 289-299. PMID: 16133905, DOI: 10.1007/s10461-005-9003-4.Peer-Reviewed Original ResearchConceptsInjection drug usersCondom useAntiretroviral therapyHIV testingDrug usersEligible injection drug usersRisk behaviorsActive antiretroviral therapyInconsistent condom useSexual risk behaviorsIDU cohortHIV transmissionRetrospective analysisLower riskStudy exposureSexual riskLong-term studiesTherapySignificant changesCounselingRiskExposureLogistic modelWidespread availabilityCohort
2004
Comparison of HIV infection risk behaviors among injection drug users from East and West Coast US cities
Garfein R, Monterroso E, Tong T, Vlahov D, Des Jarlais D, Selwyn P, Kerndt P, Word C, Fernando M, Ouellet L, Holmberg S. Comparison of HIV infection risk behaviors among injection drug users from East and West Coast US cities. Journal Of Urban Health 2004, 81: 260-267. PMID: 15136659, PMCID: PMC3456450, DOI: 10.1093/jurban/jth112.Peer-Reviewed Original ResearchConceptsInjection drug usersRisk behaviorsHIV seroprevalenceHigh human immunodeficiency virus (HIV) seroprevalenceDrug usersHIV infection risk behaviorsHuman immunodeficiency virus (HIV) seroprevalenceInfection risk behaviorsPotential risk factorsHIV risk behaviorsHIV incidenceHIV statusRisk factorsVirus seroprevalenceSexual partnersPrevention effortsSeroprevalenceBaseline dataHIVFace interviewsInjectionNew York CityFurther effortsNew HavenParticipantsIncrease in Sexual Risk Behavior Associated with Immunologic Response to Highly Active Antiretroviral Therapy among HIV-Infected Injection Drug Users
Tun W, Gange S, Vlahov D, Strathdee S, Celentano D. Increase in Sexual Risk Behavior Associated with Immunologic Response to Highly Active Antiretroviral Therapy among HIV-Infected Injection Drug Users. Clinical Infectious Diseases 2004, 38: 1167-1174. PMID: 15095224, DOI: 10.1086/383033.Peer-Reviewed Original ResearchConceptsInjection drug usersActive antiretroviral therapyHAART initiationCell countAntiretroviral therapyDrug usersSexual intercourseRisk reduction counselingHuman immunodeficiency virusLarge cohort studyDrug injection behaviorInjection of drugsUnprotected sexual intercourseSemiannual visitsReduction counselingCohort studyHIV infectionHIV serostatusImmunodeficiency virusImmunologic responseNeedle sharingBlood samplesSurvival analysisRisk behaviorsCD4Explaining the relationship between race/ethnicity and pharmacy purchased syringes among injection drug users in New York City.
Fuller C, Galea S, Blaney S, Ompad D, Deren S, Des Jarlais D, Vlahov D. Explaining the relationship between race/ethnicity and pharmacy purchased syringes among injection drug users in New York City. Ethnicity & Disease 2004, 14: 589-96. PMID: 15724781.Peer-Reviewed Original Research
2003
Retinoids and Drugs of Abuse: Implications for Neurological Disease Risk in Human Immunodeficiency Virus Type 1 Infection
Royal W, Vlahov D, Lyles C, Gajewski C. Retinoids and Drugs of Abuse: Implications for Neurological Disease Risk in Human Immunodeficiency Virus Type 1 Infection. Clinical Infectious Diseases 2003, 37: s427-s432. PMID: 14648459, DOI: 10.1086/377554.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virus type 1 (HIV-1) infectionVirus type 1 infectionType 1 infectionDrug usersSeronegative control subjectsRetinoic acidDevelopment of HIVInjection drug usersTumor necrosis factorNervous system diseasesLevels of retinolMononuclear cell lineNeurological disease riskTrans retinoic acidDrugs of abuseRetinoid administrationClinical outcomesRetinol-binding proteinImmunomodulatory effectsControl subjectsNecrosis factorSystem diseasesNeurological diseasesHIVDisease riskLongitudinal Patterns of Drug Injection Behavior in the ALIVE Study Cohort,1988–2000: Description and Determinants
Galai N, Safaeian M, Vlahov D, Bolotin A, Celentano D. Longitudinal Patterns of Drug Injection Behavior in the ALIVE Study Cohort,1988–2000: Description and Determinants. American Journal Of Epidemiology 2003, 158: 695-704. PMID: 14507606, DOI: 10.1093/aje/kwg209.Peer-Reviewed Original ResearchConceptsInjection drug usersDrug injection behaviorDrug usersIntravenous Experience (ALIVE) studyDrug treatment programsHistory of incarcerationLogistic regression modelsALIVE studySemiannual visitsMultinomial logistic regression modelsBaseline factorsChronic diseasesDrug injectionRecent overdoseCessation attemptsDrug use transitionsDrug injectorsCommunity outreach effortsLongitudinal patternsHigh mortalityEarly determinantsYounger ageTreatment programInjection behaviorStudy periodUnderstanding the dynamics of sexual transmission of HIV among drug-using populations: An integration of biological, behavioral, and environmental perspectives
Normand J, Lambert E, Vlahov D. Understanding the dynamics of sexual transmission of HIV among drug-using populations: An integration of biological, behavioral, and environmental perspectives. Journal Of Urban Health 2003, 80: iii1-iii6. PMID: 14713666, PMCID: PMC3456263, DOI: 10.1093/jurban/jtg077.Peer-Reviewed Original ResearchVariability in the Incidence of Human Immunodeficiency Virus, Hepatitis B Virus, and Hepatitis C Virus Infection among Young Injecting Drug Users in New York City
Des Jarlais D, Diaz T, Perlis T, Vlahov D, Maslow C, Latka M, Rockwell R, Edwards V, Friedman S, Monterroso E, Williams I, Garfein R. Variability in the Incidence of Human Immunodeficiency Virus, Hepatitis B Virus, and Hepatitis C Virus Infection among Young Injecting Drug Users in New York City. American Journal Of Epidemiology 2003, 157: 467-471. PMID: 12615611, DOI: 10.1093/aje/kwf222.Peer-Reviewed Original ResearchConceptsHepatitis B virusHuman immunodeficiency virusHepatitis C virusImmunodeficiency virusB virusDrug usersHepatitis C virus infectionC virus infectionInjecting Drug UsersHigh HIV seroprevalenceHigh rateHBV incidenceHCV incidenceHCV transmissionCohort studyHIV seroprevalenceHIV incidenceHIV transmissionYoung Injecting Drug UsersC virusVirus infectionNew York CityIncidenceVirusYork CitySocial Circumstances of Initiation of Injection Drug Use and Early Shooting Gallery Attendance: Implications for HIV Intervention Among Adolescent and Young Adult Injection Drug Users
Fuller C, Vlahov D, Latkin C, Ompad D, Celentano D, Strathdee S. Social Circumstances of Initiation of Injection Drug Use and Early Shooting Gallery Attendance: Implications for HIV Intervention Among Adolescent and Young Adult Injection Drug Users. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2003, 32: 86. PMID: 12514419, DOI: 10.1097/00126334-200301010-00013.Peer-Reviewed Original ResearchConceptsInjection drug usersNew injection drug usersOlder injection drug usersYoung adult injection drug usersDrug usersHigh-risk injection drug usersStreet-recruited injection drug usersAdult injection drug usersYoung injection drug usersGallery attendanceProspective cohort studyInjection drug useMultiple logistic regressionHigh-risk practicesCohort studyMedian ageHIV incidenceHIV prevalenceInnovative intervention strategiesHIV interventionsDrug useLogistic regressionHIVBaseline dataMost participants
2002
Regional variation in CCR5-Δ32 gene distribution among women from the US HIV Epidemiology Research Study (HERS)
Downer M, Hodge T, Smith D, Qari S, Schuman P, Mayer K, Klein R, Vlahov D, Gardner L, McNicholl J. Regional variation in CCR5-Δ32 gene distribution among women from the US HIV Epidemiology Research Study (HERS). Genes & Immunity 2002, 3: 295-298. PMID: 12140749, DOI: 10.1038/sj.gene.6363884.Peer-Reviewed Original ResearchConceptsHIV Epidemiology Research StudyRace/ethnicityHIV-1HIV Epidemiologic Research StudyAfrican AmericansCCR5-Δ32 genotypeHIV-1 transmissionEpidemiologic research studiesHost genetic factorsHispanic/LatinaBlack/African AmericanUninfected womenAA womenUS womenCCR5-Δ32US populationWhite womenFrequency of heterozygotesWomenGenetic factorsDistributions of heterozygotesRegional variationResearch studiesProspective study of infective endocarditis among injection drug users
Wilson L, Thomas D, Astemborski J, Freedman T, Vlahov D. Prospective study of infective endocarditis among injection drug users. The Journal Of Infectious Diseases 2002, 185: 1761-1766. PMID: 12085322, DOI: 10.1086/340827.Peer-Reviewed Original ResearchConceptsInjection drug usersInfective endocarditisHIV-seronegative injection drug usersDrug usersHuman immunodeficiency virus (HIV) infectionCohort of IDUsInjection drug use behaviorsCD4 lymphocyte countImmunodeficiency virus infectionCase-control studyDrug use frequencyDrug use behaviorsHIV immunosuppressionLymphocyte countCase patientsHIV statusAlcohol intakeProspective studyInverse associationRisk factorsVirus infectionMultivariate analysisEndocarditisHIVIncidenceHighly active antiretroviral treatment does not increase sexual risk behaviour among French HIV infected injecting drug users
Bouhnik A, Moatti J, Vlahov D, Gallais H, Dellamonica P, Obadia Y. Highly active antiretroviral treatment does not increase sexual risk behaviour among French HIV infected injecting drug users. Journal Of Epidemiology & Community Health 2002, 56: 349. PMID: 11964431, PMCID: PMC1732133, DOI: 10.1136/jech.56.5.349.Peer-Reviewed Original ResearchConceptsSexual risk behaviorsAntiretroviral treatmentDrug usersRisk behaviorsPrescription of HAARTActive antiretroviral therapyProportion of patientsActive antiretroviral treatmentUnprotected sexual intercourseFrench HIVAntiretroviral therapyClinical improvementCohort studyTreatment-NaiveHIV transmissionAIDS careHAARTHIV riskHigh-risk activitiesHospital departmentsSexual riskHIVSexual intercourseMultivariate modelLongitudinal analysisHigh Prevalence of Iron Deficiency and Anemia Among Female Injection Drug Users With and Without HIV Infection.
Semba R, Shah N, Strathdee S, Vlahov D. High Prevalence of Iron Deficiency and Anemia Among Female Injection Drug Users With and Without HIV Infection. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2002, 29: 142. PMID: 11832682, DOI: 10.1097/00042560-200202010-00005.Peer-Reviewed Original ResearchConceptsFemale injection drug usersInjection drug usersIron deficiency anemiaHIV infectionDeficiency anemiaIron deficiencyIron supplementationDrug usersHigh mortalityHepatitis C virus infectionC virus infectionHIV-negative womenHepatitis C infectionPrevalence of anemiaHepatitis C virusCross-sectional studyProgression of diseaseC infectionPlasma ferritinC virusOverall prevalenceHigh prevalenceVirus infectionAnemia patientsAnemiaRisk factors and cumulative incidence of anaemia among HIV-infected injection drug users
Semba R, Shah N, Vlahov D. Risk factors and cumulative incidence of anaemia among HIV-infected injection drug users. International Journal Of STD & AIDS 2002, 13: 119-123. PMID: 11839167, DOI: 10.1258/0956462021924758.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnemiaFemaleHIV InfectionsHumansIncidenceMaleRisk FactorsSubstance Abuse, IntravenousSurveys and QuestionnairesConceptsInjection drug usersCumulative incidenceRisk factorsDrug usersMycobacterium avium complex infectionHigher body mass indexBody mass indexLongitudinal cohort studyZidovudine useCohort studyLymphocyte countOral thrushMass indexComplex infectionFemale genderHigh riskLower riskAnemiaMicrocytic anemiaIncidenceWeight lossCells/Marijuana useRiskCD4
2001
Cancer incidence in women with or at risk for HIV
Phelps R, Smith D, Heilig C, Gardner L, Carpenter C, Klein R, Jamieson D, Vlahov D, Schuman P, Holmberg S, Group S. Cancer incidence in women with or at risk for HIV. International Journal Of Cancer 2001, 94: 753-757. PMID: 11745473, DOI: 10.1002/ijc.1528.Peer-Reviewed Original ResearchConceptsInvasive cervical cancerLung cancerHigh-risk human immunodeficiency virusRace-matched womenCurrent antiretroviral therapyHistory of smokingMonths of diagnosisInjection drug useHuman immunodeficiency virusHIV Epidemiology Research StudyCare of womenRates of cancerCancer incidence dataInterval diagnosisUninfected womenAntiretroviral therapyHIV infectionStudy closureCervical cancerImmunodeficiency virusYoung smokersHodgkin's lymphomaMedical recordsCancer incidenceKaposi's sarcomaEffects of CCR5-Delta32, CCR2-64I, and SDF-1 3'A alleles on HIV-1 disease progression: An international meta-analysis of individual-patient data.
Ioannidis J, Rosenberg P, Goedert J, Ashton L, Benfield T, Buchbinder S, Coutinho R, Eugen-Olsen J, Gallart T, Katzenstein T, Kostrikis L, Kuipers H, Louie L, Mallal S, Margolick J, Martinez O, Meyer L, Michael N, Operskalski E, Pantaleo G, Rizzardi G, Schuitemaker H, Sheppard H, Stewart G, Theodorou I, Ullum H, Vicenzi E, Vlahov D, Wilkinson D, Workman C, Zagury J, O'Brien T. Effects of CCR5-Delta32, CCR2-64I, and SDF-1 3'A alleles on HIV-1 disease progression: An international meta-analysis of individual-patient data. Annals Of Internal Medicine 2001, 135: 782-95. PMID: 11694103, DOI: 10.7326/0003-4819-135-9-200111060-00008.Peer-Reviewed Original ResearchConceptsHIV-1 infectionCCR2-64I alleleHIV-1 RNA levelsHIV-1 disease progressionDevelopment of AIDSIndividual patient dataCCR5-Delta32Decreased riskDisease progressionProtective effectLower HIV-1 RNA levelsRNA levelsProspective cohort studyCase-control studyClear protective effectStrong protective effectChemokine receptor genesRandom-effects modelCCR2-64ICohort studyStudy entryCertain chemokinesAIDSInfectionProgressionCollaboration among Community Members, Local Health Service Providers, and Researchers in an Urban Research Center in Harlem, New York
Galea S, Factor S, Bonner S, Foley M, Freudenberg N, Latka M, Palermo A, Vlahov D. Collaboration among Community Members, Local Health Service Providers, and Researchers in an Urban Research Center in Harlem, New York. Public Health Reports 2001, 116: 530-539. PMID: 12196612, PMCID: PMC1497380, DOI: 10.1093/phr/116.6.530.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAsthmaChildCommunity Health PlanningCommunity ParticipationCommunity-Institutional RelationsCooperative BehaviorDecision Making, OrganizationalHealth Planning CouncilsHealth PrioritiesHealth Services AccessibilityHealth Services ResearchHepatitis CHIV InfectionsHumansModels, OrganizationalNew York CityPublic Health AdministrationSocial EnvironmentSubstance Abuse, IntravenousUrban HealthConceptsInjection drug usersCommunity advisory boardUrban Research CenterDrug usersInfectious diseasesLocal health service providersPublic health professionalsSelf-management skillsHealth service providersUrban Epidemiologic StudiesCenter experienceAsthma awarenessEpidemiologic studiesCare providersLocal community-based organizationsHealth professionalsProblem substance useAsthmaChild care providersSubstance useEducational interventionSubstance usersCommunity healthCommunity-based organizationsIntervention