1993
Detection of Human Immunodeficiency Virus Type 1 Infection by Polymerase Chain Reaction in a Cohort of Seronegative Intravenous Drug Users
Farzadegan H, Vlahov D, Solomon L, Muñoz A, Astemborski J, Taylor E, Burnley A, Nelson K. Detection of Human Immunodeficiency Virus Type 1 Infection by Polymerase Chain Reaction in a Cohort of Seronegative Intravenous Drug Users. The Journal Of Infectious Diseases 1993, 168: 327-331. PMID: 8335969, DOI: 10.1093/infdis/168.2.327.Peer-Reviewed Original ResearchConceptsSeronegative intravenous drug usersIntravenous drug usersHuman immunodeficiency virus type 1 (HIV-1) infectionVirus type 1 infectionType 1 infectionPolymerase chain reactionDrug usersHIV-1 infectionHIV-1 antibodiesChain reactionLarge cohortBlood specimensProviral DNAInfectionCohortPCR analysisPersonsSerologyFollowVisitsAntibodiesMonthsFrequency of left ventricular dysfunction and other echocardiographic abnormalities in human immunodeficiency virus seronegative intravenous drug users
Willoughby S, Vlahov D, Herskowitz A. Frequency of left ventricular dysfunction and other echocardiographic abnormalities in human immunodeficiency virus seronegative intravenous drug users. The American Journal Of Cardiology 1993, 71: 446-447. PMID: 8430637, DOI: 10.1016/0002-9149(93)90451-h.Peer-Reviewed Original ResearchConceptsIntravenous drug usersSeronegative intravenous drug usersIllicit drug useDrug usersDrug useLeft ventricularHIV-seronegative intravenous drug usersHuman immunodeficiency virus (HIV) infectionHIV-seropositive patientsNormal coronary arteriesImmunodeficiency virus infectionLeft ventricular dysfunctionLV ejection fractionGlobal left ventricularDevelopment of cardiomyopathyEchocardiographic abnormalitiesEchocardiographic findingsLV dysfunctionSeropositive patientsVentricular dysfunctionEjection fractionHIV infectionRetrospective reviewImmunodeficiency syndromeCoronary angiogram
1992
Changes in T-Lymphocyte Subsets in Intravenous Drug Users With HIV-1 Infection
Margolick J, Muñoz A, Vlahov D, Solomon L, Astemborski J, Cohn S, Nelson K. Changes in T-Lymphocyte Subsets in Intravenous Drug Users With HIV-1 Infection. JAMA 1992, 267: 1631-1636. PMID: 1347321, DOI: 10.1001/jama.1992.03480120069035.Peer-Reviewed Original ResearchConceptsSeropositive intravenous drug usersIntravenous drug usersHIV-1 infectionHIV-1-seropositive intravenous drug usersDrug usersCell countSeronegative intravenous drug usersHuman immunodeficiency virus type 1Complete blood cell countImmunodeficiency virus type 1Absolute numberCD4 cell countCD4 lymphocyte countPercentage of CD4T lymphocyte subsetsCD8 T cellsT cell subsetsCommunity-based clinicsBlood cell countTime of seroconversionVirus type 1Multivariate regression analysisUse of drugsCD4 lymphocytesCD8 lymphocytesPrevalence of Tuberculin Positivity and Skin Test Anergy in HIV-1—Seropositive and —Seronegative Intravenous Drug Users
Graham N, Nelson K, Solomon L, Bonds M, Rizzo R, Scavotto J, Astemborski J, Vlahov D. Prevalence of Tuberculin Positivity and Skin Test Anergy in HIV-1—Seropositive and —Seronegative Intravenous Drug Users. JAMA 1992, 267: 369-373. PMID: 1727959, DOI: 10.1001/jama.1992.03480030047035.Peer-Reviewed Original ResearchConceptsIntravenous drug usersHIV-1 seropositivesSkin test anergyHIV-1 seropositive groupSeronegative intravenous drug usersTuberculin positivityLymphocyte countPPD positivityHIV-1-seropositive intravenous drug usersPPD tuberculinDrug usersHuman immunodeficiency virus serostatusSeropositive intravenous drug usersHIV-1 seropositive patientsTuberculin skin test resultsHIV-1 seronegativeHIV-1 seronegativesPPD test resultsHIV-1 seropositivityDelayed-type hypersensitivityCommunity-based cohortSkin test resultsYears of agePositive test resultsInverse linear trend
1991
HIV-1 infection and nervous system abnormalities among a cohort of intravenous drug users.
Royal W, Updike M, Seines O, Proctor T, Nance-Sproson L, Solomon L, Vlahov D, Cornblath D, McArthur J. HIV-1 infection and nervous system abnormalities among a cohort of intravenous drug users. Neurology 1991, 41: 1905-10. PMID: 1745346, DOI: 10.1212/wnl.41.12.1905.Peer-Reviewed Original ResearchConceptsHIV-1 serostatusIntravenous drug usersNeurologic abnormalitiesDrug usersSeronegative intravenous drug usersCD4 cell countHIV-seropositive subjectsHIV-1 infectionNervous system abnormalitiesConstitutional symptomsElectrophysiologic evaluationSeropositive participantsSeropositive subjectsElectrophysiologic abnormalitiesHIV infectionStudy cohortNeurologic diseaseSystem abnormalitiesHomosexual menCell countSerologic groupsCohortAbnormalitiesClear associationNeuropsychological tests