1990
Bovine papillomavirus E2 repressor mutant displays a high-copy-number phenotype and enhanced transforming activity
Riese D, Settleman J, Neary K, DiMaio D. Bovine papillomavirus E2 repressor mutant displays a high-copy-number phenotype and enhanced transforming activity. Journal Of Virology 1990, 64: 944-949. PMID: 2153255, PMCID: PMC249196, DOI: 10.1128/jvi.64.2.944-949.1990.Peer-Reviewed Original ResearchConceptsRepressor proteinWild-type copy numberBovine papillomavirus type 1 genomeCopy numberViral genomeTranscriptional repressor proteinTransient expression experimentsMouse C127 cellsMutant viral DNAViral DNAType 1 genomeNumber phenotypeRepressor activityLow copy numberMethionine codonInitiation codonExpression experimentsC127 cellsGenomeCV1 cellsRepressor mutantsFoci formationColony formationCodonProtein
1982
Bovine papillomavirus vector that propagates as a plasmid in both mouse and bacterial cells.
DiMaio D, Treisman R, Maniatis T. Bovine papillomavirus vector that propagates as a plasmid in both mouse and bacterial cells. Proceedings Of The National Academy Of Sciences Of The United States Of America 1982, 79: 4030-4034. PMID: 6287462, PMCID: PMC346570, DOI: 10.1073/pnas.79.13.4030.Peer-Reviewed Original ResearchConceptsMammalian cellsBacterial cellsInduce focus formationHuman beta-globin gene clusterBeta-globin gene clusterBPV DNADerivative of pBR322Mouse C127 cellsTransformation of bacteriaTransformed mouse cellsHuman beta-globin geneExtrachromosomal elementsGene clusterBeta-globin geneBovine papillomavirus vectorDeletion derivativesInput DNACellular genesRecombinant plasmidC127 cellsCopy numberMouse cellsTransformed cellsPlasmidFoci formation