Daniel Chamié, MD, PhD
Assistant Professor of Medicine (Cardiovascular Medicine)Cards
About
Research
Publications
2026
Artificial intelligence-based coronary computed tomography angiography quantification of atherosclerosis burden: comparison with intravascular ultrasound in the INVICTUS Registry
Nakanishi R, Okubo R, Matsuo H, Sobue Y, Kaneko U, Sato H, Fujimoto S, Nozaki Y, Kajiya T, Miyoshi T, Ichikawa K, Abe M, Kitagawa T, Ikenaga H, Osawa K, Saji M, Iguchi N, Nakazawa G, Takahashi K, Ijichi T, Mikamo H, Kurata A, Moroi M, Iijima R, Bandeira D, Demuyakor A, Parise H, Malkasian S, Mintz G, Lansky A, Earls J, Chamié D. Artificial intelligence-based coronary computed tomography angiography quantification of atherosclerosis burden: comparison with intravascular ultrasound in the INVICTUS Registry. European Radiology 2026, 1-14. PMID: 41781729, DOI: 10.1007/s00330-026-12412-y.Peer-Reviewed Original ResearchCoronary CT angiographyLow-attenuation plaqueIntravascular ultrasoundExternal elastic membranePlaque volumeImage processing timeCalcium indexElastic membraneAtherosclerosis burdenNon-calcifiedCoronary segmentsProcessing timeExternal elastic membrane volumeCoronary Computed Tomography AngiographyPredictor of cardiovascular eventsModality findingsNon-diseased segmentsTherapeutic decision-makingRoutine clinical practiceDisease severity spectrumLumen area stenosisPlaque segmentationInter-observer variabilityCardiovascular risk assessmentMinimum lumen area500.10 Association of Coronary Tortuosity on Symptom Burden in Patients with Ischemia with Nonobstructive Coronary Arteries: Insight from the DISCOVER INOCA Multicenter Registry
Ohadi L, Sohal S, Cristea E, Toleva O, Henry T, Tremmel J, Smilowitz N, Kobayashi Y, Parikh R, Henry G, Savage M, Samuels B, Lerman A, Moses J, Prasad M, Pietras C, Amenyedor K, Pandya R, Moore M, Chamié D, Latif N, Qureshi R, Dudorova E, Lansky A, Shah S. 500.10 Association of Coronary Tortuosity on Symptom Burden in Patients with Ischemia with Nonobstructive Coronary Arteries: Insight from the DISCOVER INOCA Multicenter Registry. JACC Cardiovascular Interventions 2026, 19: s49-s50. DOI: 10.1016/j.jcin.2026.01.172.Peer-Reviewed Original Research500.01 Determining the Optimal Threshold for Coronary Calcium Quantification Using AI-Based Coronary CT Angiography Analysis. Comparison With OCT in the INVICTUS Registry
Chamié D, Demuyakor A, Matsuo H, Kaneko U, Sato H, Pandya R, Fujimoto S, Kajiya T, Miyoshi T, Abe M, Kitagawa T, Osawa K, Iguchi N, Nakazawa G, Ijichi T, Mikamo H, Kurata A, Iijima R, Young R, Wiest M, Mintz G, Lansky A, Nakanishi R. 500.01 Determining the Optimal Threshold for Coronary Calcium Quantification Using AI-Based Coronary CT Angiography Analysis. Comparison With OCT in the INVICTUS Registry. JACC Cardiovascular Interventions 2026, 19: s46. DOI: 10.1016/j.jcin.2026.01.158.Peer-Reviewed Original Research500.05 Automated External Elastic Lamina Segmentation in High-Frequency OCT Using Machine Learning: Validation Against an Independent OCT Core Lab
Pandya R, Demuyakor A, Bandeira D, Tamhane A, Ughi G, Lansky A, Chamié D. 500.05 Automated External Elastic Lamina Segmentation in High-Frequency OCT Using Machine Learning: Validation Against an Independent OCT Core Lab. JACC Cardiovascular Interventions 2026, 19: s47-s48. DOI: 10.1016/j.jcin.2026.01.164.Peer-Reviewed Original ResearchAbluminus DES+ sirolimus-eluting stent versus everolimus-eluting stent in patients with diabetes and coronary artery disease (ABILITY Diabetes Global): results from a multicentre, randomised controlled trial.
Abizaid A, Mehran R, Oliva A, Chamié D, Staico R, Malik F, Vink M, Kurniadi A, Cao D, Capranzano P, Faurie B, Garot P, Hildick-Smith D, Ielasi A, Löffelhardt N, Kedev S, Mylotte D, Milewski K, Paradies V, Schmitz T, Teeuwen K, Testa L, Toelg R, Vochelet F, Vogel B, Wykrzykowska J, Sartori S, Colombo A, Saito S, Morice MC, ABILITY Diabetes Global investigators. Abluminus DES+ sirolimus-eluting stent versus everolimus-eluting stent in patients with diabetes and coronary artery disease (ABILITY Diabetes Global): results from a multicentre, randomised controlled trial. Lancet 2026, 407: 227-236. PMID: 41520674, DOI: 10.1016/S0140-6736(25)02157-9.Peer-Reviewed Original Research
2025
TCT-438 Comparison of Coronary Vessel Sizing by Artificial Intelligence-Based Coronary Computed Tomography Angiography Quantification and Intravascular Ultrasound: Insights from the INVICTUS Registry
Demuyakor A, Nakanishi R, Pandya R, Okubo R, Matsuo H, Sato H, Fujimoto S, Kajiya T, Miyoshi T, Ichikawa K, Abe M, Kitagawa T, Ikenaga H, Osawa K, Saji M, Nakazawa G, Takahashi K, Ijichi T, Mikamo H, Kurata A, Moroi M, Bandeira D, Lansky A, Mintz G, Chamie D. TCT-438 Comparison of Coronary Vessel Sizing by Artificial Intelligence-Based Coronary Computed Tomography Angiography Quantification and Intravascular Ultrasound: Insights from the INVICTUS Registry. Journal Of The American College Of Cardiology 2025, 86: b192. DOI: 10.1016/j.jacc.2025.09.558.Peer-Reviewed Original ResearchMicrobubble Contrast Agent Use During Invasive Coronary Microvascular Assessment
Bahl R, Mehta S, Seligman H, Rajkumar C, Gafore S, Sen S, Nijjer S, Al-Lamee R, Chamié D, Bandeira D, Zhou X, Shin M, Tang M, Petraco R. Microbubble Contrast Agent Use During Invasive Coronary Microvascular Assessment. Journal Of The Society For Cardiovascular Angiography & Interventions 2025, 4: 103857. PMID: 41268079, PMCID: PMC12629735, DOI: 10.1016/j.jscai.2025.103857.Peer-Reviewed Original ResearchSignal-to-noise ratioSignal qualityCoronary flow reserveDoppler signal qualityUltrasound microbubble contrast agentFlow velocityDoppler-derived coronary flow reserveAssessment of coronary flow velocityMicrovascular assessmentMicrobubble contrast agentsAdministration of SonoVueContrast agent useMicrovascular function assessmentCoronary flow velocityCFR measurementsContrast agentsDoppler signalsAgent useMicrobubble contrastFlow reserveThe Lancet Commission on rethinking coronary artery disease: moving from ischaemia to atheroma
Zaman S, Wasfy J, Kapil V, Ziaeian B, Parsonage W, Sriswasdi S, Chico T, Capodanno D, Colleran R, Sutton N, Song L, Karam N, Sofat R, Fraccaro C, Chamié D, Alasnag M, Warisawa T, Gonzalo N, Jomaa W, Mehta S, Cook E, Sundström J, Nicholls S, Shaw L, Patel M, Al-Lamee R. The Lancet Commission on rethinking coronary artery disease: moving from ischaemia to atheroma. The Lancet 2025, 405: 1264-1312. PMID: 40179933, PMCID: PMC12315672, DOI: 10.1016/s0140-6736(25)00055-8.Peer-Reviewed Original ResearchCan AI Capture and Quantify Clinical Expertise? Implications for Intracoronary Imaging in Percutaneous Coronary Intervention
Petraco R, Bahl R, Almeida G, Bandeira D, Seligman H, Alloula A, Demuyakor A, Lansky A, Johnson T, Francis D, Mintz G, Shun-Shin M, Chamié D. Can AI Capture and Quantify Clinical Expertise? Implications for Intracoronary Imaging in Percutaneous Coronary Intervention. Journal Of The Society For Cardiovascular Angiography & Interventions 2025, 4: 102523. PMID: 40230670, PMCID: PMC11993851, DOI: 10.1016/j.jscai.2024.102523.Peer-Reviewed Original ResearchHigh-Frequency Optical Coherence Tomography: Addressing Common Pitfalls of Traditional Optical Coherence Tomography Imaging
Case B, Wallace R, Chamié D. High-Frequency Optical Coherence Tomography: Addressing Common Pitfalls of Traditional Optical Coherence Tomography Imaging. Journal Of The Society For Cardiovascular Angiography & Interventions 2025, 4: 102621. PMID: 40231051, PMCID: PMC11993861, DOI: 10.1016/j.jscai.2025.102621.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
News
News
- December 09, 2025
Building a Career in Cutting-Edge Intravascular Imaging
- October 28, 2025Source: JSCAI: Conversations in Interventional Cardiology
Coronary Compliance Modification by Intravascular Lithotripsy: New Predictor of Stent Expansion in Calcified Coronary Lesions
- October 21, 2025Source: JSCAI: Conversations in Interventional Cardiology
High-Definition Intravascular Ultrasound Versus Optical Coherence Tomography: Lumen Size and Plaque Morphology
- August 07, 2025Source: Clinical Trial Results
Dr. Daniel Chamie and Dr. C. Michael Gibson discuss: Clinical Utility of Atherosclerosis Imaging: Lessons Learned from Intravascular Ultrasound
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Mailing Address
Yale School of Medicine
135 College Street
New Haven, Connecticut 06510
United States