2024
Compartmentalized pooling generates orientation selectivity in wide-field amacrine cells
Lei W, Clark D, Demb J. Compartmentalized pooling generates orientation selectivity in wide-field amacrine cells. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2411130121. PMID: 39602271, PMCID: PMC11626119, DOI: 10.1073/pnas.2411130121.Peer-Reviewed Original ResearchConceptsOrientation selectivityBand-pass spatial frequency tuningVisual systemReceptive fieldsSpatial frequency tuningWide-field amacrine cellsReceptive field modelOrientation detectionKappa-opioid receptorsAmacrine cellsDetecting orientationVisual sceneFrequency tuningGlycinergic inhibitionOpioid receptorsField modelSpecific membrane resistanceExcitatory inputSynaptic inputsCalcium imagingMouse retinaCalcium signalingDendritic compartmentsMicrocircuit levelPolarization
2023
Direct comparison reveals algorithmic similarities in fly and mouse visual motion detection
Chen J, Gish C, Fransen J, Salazar-Gatzimas E, Clark D, Borghuis B. Direct comparison reveals algorithmic similarities in fly and mouse visual motion detection. IScience 2023, 26: 107928. PMID: 37810236, PMCID: PMC10550730, DOI: 10.1016/j.isci.2023.107928.Peer-Reviewed Original ResearchMolecular mechanismsStarburst amacrine cellsSpatiotemporal receptive-field structureReceptive field structureAmacrine cellsT4 neuronsSpeciesNeuronal morphologyNeuron typesAnalogous neuronsNeural circuitsVisual motion detectionCellsVisual motionMotion stimuliVertebratesInvertebratesMiceMotion processingNeuronsSimilarityApparent motion stimuliFlies