2021
Learning From England's Best Practice Tariff
Zogg CK, Metcalfe D, Judge A, Perry DC, Costa ML, Gabbe BJ, Schoenfeld AJ, Davis KA, Cooper Z, Lichtman JH. Learning From England's Best Practice Tariff. Annals Of Surgery 2021, 275: 506-514. PMID: 33491982, PMCID: PMC9233527, DOI: 10.1097/sla.0000000000004305.Peer-Reviewed Original Research
2020
Epidemiology, treatment, survival, and prognostic factors of cutaneous mucoepidermoid carcinoma: A distinct entity with an indolent clinical course
Mirza FN, Yumeen S, Zogg CK, Mirza HN, Leventhal JS. Epidemiology, treatment, survival, and prognostic factors of cutaneous mucoepidermoid carcinoma: A distinct entity with an indolent clinical course. Journal Of The American Academy Of Dermatology 2020, 83: 1827-1830. PMID: 32446830, PMCID: PMC7669598, DOI: 10.1016/j.jaad.2020.05.086.Peer-Reviewed Original ResearchQuantifying the Impact of Care Fragmentation on Outcomes After Transcatheter Aortic Valve Implantation
Hirji SA, Zogg CK, Vaduganathan M, Kiehm S, Percy ED, Yazdchi F, Pelletier M, Shah PB, Bhatt DL, O'Gara P, Kaneko T. Quantifying the Impact of Care Fragmentation on Outcomes After Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2020, 128: 113-119. PMID: 32650903, DOI: 10.1016/j.amjcard.2020.05.005.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCardiac CatheterizationCenters for Medicare and Medicaid Services, U.S.ComorbidityContinuity of Patient CareCoronary AngiographyDiabetes MellitusFemaleHospital CostsHospital MortalityHospitalsHumansHypertensionLength of StayLung DiseasesMaleMultivariate AnalysisPacemaker, ArtificialPatient ReadmissionPericardiocentesisPostoperative ComplicationsProsthesis ImplantationStrokeTranscatheter Aortic Valve ReplacementUnited StatesConceptsNonindex hospitalNonindex readmissionsCare fragmentationTranscatheter aortic valve implantation outcomesTranscatheter aortic valve implantationHigher co-morbidity burdenNational Readmission DatabaseAortic valve implantationCo-morbidity burdenTotal hospital costsMajor cardiac proceduresUS adult patientsFuture health policyValue of careIndex readmissionTAVI patientsCause mortalityIndex hospitalNoncardiac causesAdult patientsPatient characteristicsReadmission ratesValve implantationReadmission lengthCardiac proceduresThirty- and 90-Day Readmissions After Treatment of Traumatic Subdural Hematoma: National Trend Analysis
Koo AB, Elsamadicy AA, David WB, Zogg CK, Santarosa C, Sujijantarat N, Robert SM, Kundishora AJ, Cord BJ, Hebert R, Bahrassa F, Malhotra A, Matouk CC. Thirty- and 90-Day Readmissions After Treatment of Traumatic Subdural Hematoma: National Trend Analysis. World Neurosurgery 2020, 139: e212-e219. PMID: 32272271, PMCID: PMC7380544, DOI: 10.1016/j.wneu.2020.03.168.Peer-Reviewed Original ResearchConceptsTraumatic subdural hematomaSubdural hematomaRheumatoid arthritis/collagen vascular diseasesMultivariate logistic regression analysisCollagen vascular diseaseNationwide Readmissions DatabaseCongestive heart failureLikelihood of readmissionPrimary procedure codeTraumatic brain injuryLogistic regression analysisReadmission ratesRenal failureHeart failurePostoperative infectionNinth RevisionSurgical interventionPatient populationVascular diseaseCerebral meningesBrain injuryClinical ModificationPatient managementReadmissionInternational ClassificationUnderweight patients are at just as much risk as super morbidly obese patients when undergoing anterior cervical spine surgery
Ottesen TD, Malpani R, Galivanche AR, Zogg CK, Varthi AG, Grauer JN. Underweight patients are at just as much risk as super morbidly obese patients when undergoing anterior cervical spine surgery. The Spine Journal 2020, 20: 1085-1095. PMID: 32194246, PMCID: PMC7380546, DOI: 10.1016/j.spinee.2020.03.007.Peer-Reviewed Original ResearchConceptsAnterior cervical spine surgeryBody mass indexCervical spine surgeryNational Surgical Quality Improvement Program databaseSuper morbidly obese patientsQuality Improvement Program databaseWorld Health Organization categoriesMorbidly obese patientsImprovement Program databaseObese patientsAdverse eventsAdverse outcomesSpine surgeryUnderweight patientsPostoperative infectionProgram databaseSurgeons National Surgical Quality Improvement Program databaseMultivariate analysisAnterior cervical spine proceduresOverweight/obese categoriesThirty-day adverse eventsHigher body mass indexLower body mass indexAdverse outcome categoriesNormal BMI patientsHospital Variation in Geriatric Surgical Safety for Emergency Operation
Becher RD, Sukumar N, DeWane MP, Stolar MJ, Gill TM, Schuster KM, Maung AA, Zogg CK, Davis KA. Hospital Variation in Geriatric Surgical Safety for Emergency Operation. Journal Of The American College Of Surgeons 2020, 230: 966-973.e10. PMID: 32032720, PMCID: PMC7409563, DOI: 10.1016/j.jamcollsurg.2019.10.018.Peer-Reviewed Original ResearchConceptsStandardized mortality ratioHospital-level characteristicsGeneral surgery operationsGeriatric patientsEmergency operationHospital variationEmergency general surgery operationsMean standardized mortality ratioCalifornia State Inpatient DatabaseHospital-based mortalitySignificant hospital variationPatients 65 yearsSubstantial excess mortalitySurgery operationsState Inpatient DatabasesMixed effects logistic regression modelsCommon general surgery operationsLow-mortality outliersLogistic regression modelsPostoperative mortalityHospital deathOlder patientsInpatient DatabaseMortality outcomesNonelective operationsThirty-Day Nonindex Readmissions and Clinical Outcomes After Cardiac Surgery
Hirji SA, Percy ED, Zogg CK, Vaduganathan M, Kiehm S, Pelletier M, Kaneko T. Thirty-Day Nonindex Readmissions and Clinical Outcomes After Cardiac Surgery. The Annals Of Thoracic Surgery 2020, 110: 484-491. PMID: 31972128, PMCID: PMC7382395, DOI: 10.1016/j.athoracsur.2019.11.042.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementNonindex readmissionsCardiac surgeryNonindex hospitalNonindex hospital readmissionsCoronary artery bypassNational Readmission DatabaseAortic valve replacementCardiac surgery patientsMajor cardiac surgeryPatient risk profileHigh-volume centersUS adult patientsRegionalization of careFragmentation of careComorbidity burdenHospital mortalityIndex readmissionArtery bypassInitial hospitalizationAdult patientsSurgery patientsValve replacementHospital readmissionIndependent predictors
2019
Coding algorithms for defining Charlson and Elixhauser co-morbidities in Read-coded databases
Metcalfe D, Masters J, Delmestri A, Judge A, Perry D, Zogg C, Gabbe B, Costa M. Coding algorithms for defining Charlson and Elixhauser co-morbidities in Read-coded databases. BMC Medical Research Methodology 2019, 19: 115. PMID: 31170931, PMCID: PMC6554904, DOI: 10.1186/s12874-019-0753-5.Peer-Reviewed Original ResearchConceptsCharlson Comorbidity IndexClinical Practice Research DatalinkElixhauser methodHip fractureLogistic regression modelsRead codesLarge primary care databaseUK primary care practicesPrimary care databasePrimary care practicesComorbidity categoriesComorbidity indexRegression modelsComorbidity measuresCare databaseComorbidity codesMethodsTwo researchersPredictive valueCare practicesControl populationPredictive propertiesReceiver Operating Characteristic (ROC) curveCharacteristic curveComorbiditiesOperating Characteristic curveTotal hip arthroplasty versus hemiarthroplasty for independently mobile older adults with intracapsular hip fractures
Metcalfe D, Judge A, Perry DC, Gabbe B, Zogg CK, Costa ML. Total hip arthroplasty versus hemiarthroplasty for independently mobile older adults with intracapsular hip fractures. BMC Musculoskeletal Disorders 2019, 20: 226. PMID: 31101041, PMCID: PMC6525472, DOI: 10.1186/s12891-019-2590-4.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overArthroplasty, Replacement, HipFemur HeadFracture DislocationHemiarthroplastyHip FracturesHumansIndependent LivingMiddle AgedPatient SelectionPostoperative ComplicationsQuality of LifeRandomized Controlled Trials as TopicRegistriesReoperationRisk FactorsUnited KingdomConceptsTotal hip arthroplastyNational Hip Fracture DatabaseHospital Episode StatisticsHip fractureIntracapsular hip fracturesMobile older adultsTHA dislocationOlder adultsHip arthroplastyPropensity scoreHealth-related qualityHip Fracture DatabaseClinical registry dataLength of stayMethodsA systematic reviewUrgent further studyDeath registration dataResultsFive RCTsFit patientsSecondary outcomesPrimary outcomeEpisode StatisticsSafety profileSurgical interventionFunctional outcome
2018
Racial/Ethnic Disparities in Longer-term Outcomes Among Emergency General Surgery Patients
Zogg CK, Jiang W, Ottesen TD, Shafi S, Schuster K, Becher R, Davis KA, Haider AH. Racial/Ethnic Disparities in Longer-term Outcomes Among Emergency General Surgery Patients. Annals Of Surgery 2018, 268: 968-979. PMID: 28742704, PMCID: PMC5783796, DOI: 10.1097/sla.0000000000002449.Peer-Reviewed Original ResearchConceptsEmergency general surgery patientsNon-Hispanic whitesGeneral surgery patientsLong-term outcomesNon-Hispanic blacksNon-Hispanic AsiansMinority patientsMajor morbidityUnplanned readmissionSurgery patientsOlder adultsRisk-adjusted Cox proportional hazards modelsEthnic disparitiesCox proportional hazards modelDiagnostic categoriesRacial/Ethnic DisparitiesUS population agesProportional hazards modelNHB patientsNonagenarian patientsNHW patientsBACKGROUND DATAHospital's percentageMortality differencesMedicare dataChanging prognosis of oral cancer: An analysis of survival and treatment between 1973 and 2014
Cheraghlou S, Schettino A, Zogg CK, Judson BL. Changing prognosis of oral cancer: An analysis of survival and treatment between 1973 and 2014. The Laryngoscope 2018, 128: 2762-2769. PMID: 30194691, DOI: 10.1002/lary.27315.Peer-Reviewed Original ResearchConceptsOral cavity cancerLate-stage diseaseAdjuvant therapyOral cancerEnd Results 9 registriesCox survival regressionHigher nodal yieldsNational Cancer DatabaseEarly-stage diseaseKaplan-Meier analysisRetrospective database analysisAnalysis of survivalAdjuvant chemoradiotherapyNodal yieldAdult patientsNeck dissectionRetrospective studyCancer DatabasePrognosisPatientsCancerDiseaseDatabase analysisSurvival regressionChemoradiotherapyManagement of metastatic melanoma: improved survival in a national cohort following the approvals of checkpoint blockade immunotherapies and targeted therapies
Dobry AS, Zogg CK, Hodi FS, Smith TR, Ott PA, Iorgulescu JB. Management of metastatic melanoma: improved survival in a national cohort following the approvals of checkpoint blockade immunotherapies and targeted therapies. Cancer Immunology, Immunotherapy 2018, 67: 1833-1844. PMID: 30191256, PMCID: PMC6249064, DOI: 10.1007/s00262-018-2241-x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAntineoplastic Agents, ImmunologicalComorbidityDisease ManagementFemaleHealth Care SurveysHumansImmunotherapyMaleMelanomaMiddle AgedMolecular Targeted TherapyNeoplasm StagingOdds RatioProtein Kinase InhibitorsProto-Oncogene Proteins B-rafRegistriesSymptom AssessmentUnited StatesYoung AdultConceptsStage 4 melanomaOverall survivalInitial approvalCutaneous melanomaLandmark survival analysisSubstantial clinical efficacyImproved overall survivalMetastatic cutaneous melanomaNational Cancer DatabaseStage 4 diseaseCheckpoint blockade immunotherapySurvival of patientsRisk-adjusted analysisBlockade immunotherapyCheckpoint blockadeNovel immunotherapiesMultivariable analysisClinical efficacyMetastatic melanomaNational cohortCancer DatabaseUninsured patientsClinical trialsPatientsSurvival analysisImproved Risk-Adjusted Survival for Melanoma Brain Metastases in the Era of Checkpoint Blockade Immunotherapies: Results from a National Cohort
Iorgulescu JB, Harary M, Zogg CK, Ligon KL, Reardon DA, Hodi FS, Aizer AA, Smith TR. Improved Risk-Adjusted Survival for Melanoma Brain Metastases in the Era of Checkpoint Blockade Immunotherapies: Results from a National Cohort. Cancer Immunology Research 2018, 6: 1039-1045. PMID: 30002157, PMCID: PMC6230261, DOI: 10.1158/2326-6066.cir-18-0067.Peer-Reviewed Original ResearchConceptsMelanoma brain metastasesCheckpoint blockade immunotherapyMBM patientsOverall survivalBlockade immunotherapyStage 4 melanomaNational Cancer DatabaseManagement of patientsKaplan-Meier techniqueLarge national cohortEarly clinical trialsBrain metastasesExtracranial metastasesSurvival benefitAdvanced melanomaOS improvementNational cohortCancer DatabaseClinical trialsNovel therapiesU.S. cancerPatientsTherapy trialsProportional hazardsFDA approvalThe Cost of Complications Following Major Resection of Malignant Neoplasia
Zogg CK, Ottesen TD, Kebaish KJ, Galivanche A, Murthy S, Changoor NR, Zogg DL, Pawlik TM, Haider AH. The Cost of Complications Following Major Resection of Malignant Neoplasia. Journal Of Gastrointestinal Surgery 2018, 22: 1976-1986. PMID: 29946953, PMCID: PMC6224301, DOI: 10.1007/s11605-018-3850-6.Peer-Reviewed Original ResearchConceptsIncremental hospital costsHospital costsMalignant neoplasiaMajor resectionResection typePre-discharge complicationsSystem-based complicationsImpact of complicationsComplex surgical patientsCost of complicationsLong-term treatmentMore complex patientsMajor gastrointestinal resectionsProviders/payersValue of carePulmonary complicationsUrinary complicationsComplication groupInfectious complicationsAdult patientsRectal resectionSurgical patientsGastrointestinal resectionGI diseaseSurgical outcomesDialysis Patients Undergoing Total Knee Arthroplasty Have Significantly Increased Odds of Perioperative Adverse Events Independent of Demographic and Comorbidity Factors
Ottesen TD, Zogg CK, Haynes MS, Malpani R, Bellamkonda KS, Grauer JN. Dialysis Patients Undergoing Total Knee Arthroplasty Have Significantly Increased Odds of Perioperative Adverse Events Independent of Demographic and Comorbidity Factors. The Journal Of Arthroplasty 2018, 33: 2827-2834. PMID: 29754981, DOI: 10.1016/j.arth.2018.04.012.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overArthroplasty, Replacement, KneeComorbidityElective Surgical ProceduresFemaleHumansInpatientsLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPatient DischargePatient ReadmissionPostoperative ComplicationsQuality ImprovementRegression AnalysisRenal DialysisReoperationRetrospective StudiesRisk AssessmentConceptsTotal knee arthroplastyDialysis-dependent patientsAdverse eventsPatient demographicsDialysis patientsAdverse outcomesKnee arthroplastyNational Surgical Quality Improvement Program databaseOverall healthRisk-adjusted logistic regressionElective total knee arthroplastyQuality Improvement Program databaseImprovement Program databaseMinor adverse eventsNational inpatient databaseSevere adverse eventsBone health statusNondialysis cohortNondialysis patientsPerioperative periodTKA patientsAdult patientsPreoperative riskComorbidity factorsInstitutional cohort
2017
Epidemiology of malignant cutaneous granular cell tumors: A US population-based cohort analysis using the Surveillance, Epidemiology, and End Results (SEER) database
Mirza FN, Tuggle CT, Zogg CK, Mirza HN, Narayan D. Epidemiology of malignant cutaneous granular cell tumors: A US population-based cohort analysis using the Surveillance, Epidemiology, and End Results (SEER) database. Journal Of The American Academy Of Dermatology 2017, 78: 490-497.e1. PMID: 28989104, PMCID: PMC5815907, DOI: 10.1016/j.jaad.2017.09.062.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBlack or African AmericanChildFemaleGranular Cell TumorHumansIncidenceKaplan-Meier EstimateKidney NeoplasmsMaleMiddle AgedNeoplasm StagingPancreatic NeoplasmsResidence CharacteristicsRetrospective StudiesSEER ProgramSex FactorsSkin NeoplasmsSurvival RateUnited StatesWhite PeopleYoung AdultConceptsDisease-specific survivalCutaneous granular cell tumorsPopulation-based cohort analysisEnd Results (SEER) databaseMedian survival timeGranular cell tumorSurgical resectionResults databaseCell tumorsCohort analysisSurvival timeCox proportional hazards regressionPoor disease-specific survivalRisk-adjusted associationHigh-risk patientsEnd Results (SEER) dataProportional hazards regressionSingle-institution studyAdvanced cancer stageRisk-adjusted modelsDSS ratesOverall survivalPatient characteristicsSubstantial morbiditySecondary malignanciesDifferences in rural and urban outcomes: a national inspection of emergency general surgery patients
Chaudhary MA, Shah AA, Zogg CK, Changoor N, Chao G, Nitzschke S, Havens JM, Haider AH. Differences in rural and urban outcomes: a national inspection of emergency general surgery patients. Journal Of Surgical Research 2017, 218: 277-284. PMID: 28985861, DOI: 10.1016/j.jss.2017.06.034.Peer-Reviewed Original ResearchConceptsLength of stayRural patientsEGS conditionsUrban hospitalOverall oddsEmergency general surgery conditionsEmergency general surgery patientsShorter LOSGeneral surgery patientsPatient-level factorsLimited clinical importanceNational Inpatient SampleSurgery of TraumaRegionalization of careCost of careMultivariable regression modelsUnited States populationHospital mortalityEGS patientsSurgery patientsUrban patientsAdult patientsMajor complicationsPrimary diagnosisInpatient Sample
2016
Factors associated with health-related quality of life (HRQOL) in adults with short stature skeletal dysplasias
Dhiman N, Albaghdadi A, Zogg CK, Sharma M, Hoover-Fong JE, Ain MC, Haider AH. Factors associated with health-related quality of life (HRQOL) in adults with short stature skeletal dysplasias. Quality Of Life Research 2016, 26: 1337-1348. PMID: 27866314, DOI: 10.1007/s11136-016-1455-7.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedOsteochondrodysplasiasSickness Impact ProfileSurveys and QuestionnairesYoung AdultConceptsShort stature skeletal dysplasiasHealth-related qualitySpondyloepiphyseal dysplasia congenitaSkeletal dysplasiaHRQoL of adultsMultivariable logistic regressionDecade of ageHealth care providersSF-12 componentsLower scoresHealth insurance coverageMedian PCSPain prevalenceHRQoL scoresPain specialistsLower HRQoLResultsA totalLower PCSSF-12High prevalenceCare providersHealth disparitiesHRQoLLogistic regressionDysplasiaGeographic Distribution of Trauma Burden, Mortality, and Services in the United States: Does Availability Correspond to Patient Need?
Rios-Diaz AJ, Metcalfe D, Olufajo OA, Zogg CK, Yorkgitis B, Singh M, Haider AH, Salim A. Geographic Distribution of Trauma Burden, Mortality, and Services in the United States: Does Availability Correspond to Patient Need? Journal Of The American College Of Surgeons 2016, 223: 764-773.e2. PMID: 28193322, DOI: 10.1016/j.jamcollsurg.2016.08.569.Peer-Reviewed Original ResearchConceptsLevel II trauma centerAge-adjusted mortality ratesTrauma admissionsTrauma centerTrauma serviceTrauma mortalityTrauma burdenMortality rateTrauma care provisionAge-adjusted mortalityCritical care providersTrauma patientsTrauma careCare providersLevel IPatient needsAdmissionProvider densitySurgeon availabilityQuality careMortalityCare provisionSCC fellowshipsAssociationCareImplementation of a Comprehensive Post-Discharge Venous Thromboembolism Prophylaxis Program for Abdominal and Pelvic Surgery Patients
Najjar PA, Madenci AL, Zogg CK, Schneider EB, Dankers CA, Pimentel MT, Chabria AS, Goldberg JE, Sharma G, Piazza G, Bleday R, Orgill DP, Kachalia A. Implementation of a Comprehensive Post-Discharge Venous Thromboembolism Prophylaxis Program for Abdominal and Pelvic Surgery Patients. Journal Of The American College Of Surgeons 2016, 223: 804-813. PMID: 27693288, PMCID: PMC6309555, DOI: 10.1016/j.jamcollsurg.2016.09.010.Peer-Reviewed Original ResearchConceptsPost-intervention cohortPre-intervention cohortInflammatory bowel diseaseVenous thromboembolismProphylaxis programAbdominal surgeryBowel diseasePost-discharge VTE ratesVenous thromboembolism prophylaxis programBedside medication deliveryInpatient venous thromboembolismInstitutional American CollegeSymptomatic venous thromboembolismPrimary end pointMajor abdominal surgeryVTE prevention programSingle-institution retrospectiveSurgeons NSQIP datasetPost-intervention analysisProphylactic anticoagulationVTE prophylaxisVTE ratesVTE eventsNSQIP datasetRisk patients