2022
National outcomes following benign cardiac tumor resection: A critical sex‐based disparity
Newell P, Zogg CK, Kusner J, Hirji S, Kerolos M, Kaneko T. National outcomes following benign cardiac tumor resection: A critical sex‐based disparity. Journal Of Cardiac Surgery 2022, 37: 2653-2660. PMID: 35662249, DOI: 10.1111/jocs.16654.Peer-Reviewed Original ResearchMeSH KeywordsComorbidityDatabases, FactualFemaleHeart NeoplasmsHumansMaleMiddle AgedPatient ReadmissionRisk FactorsConceptsComposite morbiditySurgical resectionIndependent predictorsMultivariable analysisVentricular tumorsFemale sexBenign primary cardiac tumorsCardiac tumor resectionLower comorbidity burdenPrimary cardiac tumorsNationwide Readmissions DatabaseMajority of patientsIntra-atrial septumNational outcomesSex-based disparitiesComorbidity burdenCardiac tumorsPrimary outcomeFemale patientsMean ageVentricular septumPrimary diagnosisRight atriumTumor locationTumor resection
2020
Resumption of Otolaryngology Surgical Practice in the Setting of Regionally Receding COVID-19
Izreig S, Zogg CK, Kasle DA, Torabi SJ, Manes RP. Resumption of Otolaryngology Surgical Practice in the Setting of Regionally Receding COVID-19. Otolaryngology 2020, 164: 788-791. PMID: 32957825, DOI: 10.1177/0194599820959671.Peer-Reviewed Original ResearchConceptsOngoing coronavirus disease 2019 (COVID-19) pandemicCoronavirus disease 2019 (COVID-19) pandemicPractice of otolaryngologyDisease 2019 pandemicCOVID-19 burdenCOVID-19 incidenceIncident COVID-19 casesCOVID-19 casesSurgical careSurgical proceduresAnticipatory guidanceSurgical practiceCOVID-19COVID-19 pandemicPandemicCOVID-19 dynamicsGeographic heterogeneityIncidenceQuantifying the Impact of Care Fragmentation on Outcomes After Transcatheter Aortic Valve Implantation
Hirji SA, Zogg CK, Vaduganathan M, Kiehm S, Percy ED, Yazdchi F, Pelletier M, Shah PB, Bhatt DL, O'Gara P, Kaneko T. Quantifying the Impact of Care Fragmentation on Outcomes After Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2020, 128: 113-119. PMID: 32650903, DOI: 10.1016/j.amjcard.2020.05.005.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCardiac CatheterizationCenters for Medicare and Medicaid Services, U.S.ComorbidityContinuity of Patient CareCoronary AngiographyDiabetes MellitusFemaleHospital CostsHospital MortalityHospitalsHumansHypertensionLength of StayLung DiseasesMaleMultivariate AnalysisPacemaker, ArtificialPatient ReadmissionPericardiocentesisPostoperative ComplicationsProsthesis ImplantationStrokeTranscatheter Aortic Valve ReplacementUnited StatesConceptsNonindex hospitalNonindex readmissionsCare fragmentationTranscatheter aortic valve implantation outcomesTranscatheter aortic valve implantationHigher co-morbidity burdenNational Readmission DatabaseAortic valve implantationCo-morbidity burdenTotal hospital costsMajor cardiac proceduresUS adult patientsFuture health policyValue of careIndex readmissionTAVI patientsCause mortalityIndex hospitalNoncardiac causesAdult patientsPatient characteristicsReadmission ratesValve implantationReadmission lengthCardiac procedures
2019
Coding algorithms for defining Charlson and Elixhauser co-morbidities in Read-coded databases
Metcalfe D, Masters J, Delmestri A, Judge A, Perry D, Zogg C, Gabbe B, Costa M. Coding algorithms for defining Charlson and Elixhauser co-morbidities in Read-coded databases. BMC Medical Research Methodology 2019, 19: 115. PMID: 31170931, PMCID: PMC6554904, DOI: 10.1186/s12874-019-0753-5.Peer-Reviewed Original ResearchConceptsCharlson Comorbidity IndexClinical Practice Research DatalinkElixhauser methodHip fractureLogistic regression modelsRead codesLarge primary care databaseUK primary care practicesPrimary care databasePrimary care practicesComorbidity categoriesComorbidity indexRegression modelsComorbidity measuresCare databaseComorbidity codesMethodsTwo researchersPredictive valueCare practicesControl populationPredictive propertiesReceiver Operating Characteristic (ROC) curveCharacteristic curveComorbiditiesOperating Characteristic curve
2018
Management of metastatic melanoma: improved survival in a national cohort following the approvals of checkpoint blockade immunotherapies and targeted therapies
Dobry AS, Zogg CK, Hodi FS, Smith TR, Ott PA, Iorgulescu JB. Management of metastatic melanoma: improved survival in a national cohort following the approvals of checkpoint blockade immunotherapies and targeted therapies. Cancer Immunology, Immunotherapy 2018, 67: 1833-1844. PMID: 30191256, PMCID: PMC6249064, DOI: 10.1007/s00262-018-2241-x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAntineoplastic Agents, ImmunologicalComorbidityDisease ManagementFemaleHealth Care SurveysHumansImmunotherapyMaleMelanomaMiddle AgedMolecular Targeted TherapyNeoplasm StagingOdds RatioProtein Kinase InhibitorsProto-Oncogene Proteins B-rafRegistriesSymptom AssessmentUnited StatesYoung AdultConceptsStage 4 melanomaOverall survivalInitial approvalCutaneous melanomaLandmark survival analysisSubstantial clinical efficacyImproved overall survivalMetastatic cutaneous melanomaNational Cancer DatabaseStage 4 diseaseCheckpoint blockade immunotherapySurvival of patientsRisk-adjusted analysisBlockade immunotherapyCheckpoint blockadeNovel immunotherapiesMultivariable analysisClinical efficacyMetastatic melanomaNational cohortCancer DatabaseUninsured patientsClinical trialsPatientsSurvival analysisDialysis Patients Undergoing Total Knee Arthroplasty Have Significantly Increased Odds of Perioperative Adverse Events Independent of Demographic and Comorbidity Factors
Ottesen TD, Zogg CK, Haynes MS, Malpani R, Bellamkonda KS, Grauer JN. Dialysis Patients Undergoing Total Knee Arthroplasty Have Significantly Increased Odds of Perioperative Adverse Events Independent of Demographic and Comorbidity Factors. The Journal Of Arthroplasty 2018, 33: 2827-2834. PMID: 29754981, DOI: 10.1016/j.arth.2018.04.012.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overArthroplasty, Replacement, KneeComorbidityElective Surgical ProceduresFemaleHumansInpatientsLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPatient DischargePatient ReadmissionPostoperative ComplicationsQuality ImprovementRegression AnalysisRenal DialysisReoperationRetrospective StudiesRisk AssessmentConceptsTotal knee arthroplastyDialysis-dependent patientsAdverse eventsPatient demographicsDialysis patientsAdverse outcomesKnee arthroplastyNational Surgical Quality Improvement Program databaseOverall healthRisk-adjusted logistic regressionElective total knee arthroplastyQuality Improvement Program databaseImprovement Program databaseMinor adverse eventsNational inpatient databaseSevere adverse eventsBone health statusNondialysis cohortNondialysis patientsPerioperative periodTKA patientsAdult patientsPreoperative riskComorbidity factorsInstitutional cohort
2016
Unplanned 30-day readmissions in orthopaedic trauma
Metcalfe D, Olufajo OA, Zogg CK, Rios-Diaz A, Harris M, Weaver MJ, Haider AH, Salim A. Unplanned 30-day readmissions in orthopaedic trauma. Injury 2016, 47: 1794-1797. PMID: 27262770, DOI: 10.1016/j.injury.2016.05.007.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedCaliforniaChildChild, PreschoolComorbidityFemaleHumansInfantMaleMiddle AgedOrthopedic ProceduresPatient ReadmissionPostoperative ComplicationsQuality Indicators, Health CareRetrospective StudiesRisk FactorsSocioeconomic FactorsSurgical Wound InfectionTime FactorsWounds and InjuriesYoung AdultConceptsTrauma patientsCharlson Comorbidity IndexOverall readmission rateOrthopaedic trauma patientsPrimary outcome measureHospital quality metricsUnplanned readmission riskTrauma readmissionsComorbidity indexInitial hospitalizationReadmission ratesHospital readmissionPatient factorsProcedural complicationsTrauma admissionsMale sexReadmission riskSpinal fracturesCardiopulmonary diseaseBlack racePrimary diagnosisAcute hospitalsMusculoskeletal problemsObservational studyMedical advice
2015
Morbidity or mortality? Variations in trauma centres in the rescue of older injured patients
Zafar SN, Shah AA, Zogg CK, Hashmi ZG, Greene WR, Haut ER, Cornwell EE, Haider AH. Morbidity or mortality? Variations in trauma centres in the rescue of older injured patients. Injury 2015, 47: 1091-1097. PMID: 26724172, DOI: 10.1016/j.injury.2015.11.044.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAgedAged, 80 and overComorbidityDatabases, FactualFailure to Rescue, Health CareFemaleGeriatric AssessmentHospital MortalityHumansInjury Severity ScoreLength of StayMaleMedicaidPneumoniaPostoperative ComplicationsRespiratory Distress SyndromeRisk AssessmentTrauma CentersUnited StatesWounds and InjuriesConceptsOlder trauma patientsMajor complicationsTrauma centerOld traumaRisk-adjusted ratesOlder patientsTrauma patientsNational Trauma Data BankFacility-level covariatesRisk-adjusted incidenceTrauma Data BankProcess of careType of injuryLogistic regression analysisPatient demographicsGeriatric traumaComorbid conditionsGeriatric patientsHigher proportionSerious complicationsInclusion criteriaInjury severityPatientsRescue ratesVital signsNational estimates of predictors of outcomes for emergency general surgery
Shah AA, Haider AH, Zogg CK, Schwartz DA, Haut ER, Zafar SN, Schneider EB, Velopulos CG, Shafi S, Zafar H, Efron DT. National estimates of predictors of outcomes for emergency general surgery. Journal Of Trauma And Acute Care Surgery 2015, 78: 482-491. PMID: 25710417, DOI: 10.1097/ta.0000000000000555.Peer-Reviewed Original ResearchConceptsEmergency general surgeryEGS patientsMajor complicationsGeneral surgeryMultivariate logistic regression analysisOverall complication ratePredictors of mortalityClinical Modification codesOverall mortality rateNationwide Inpatient SampleSeparate multivariate logistic regression analysesSurgery of TraumaDRG International ClassificationLogistic regression analysisHighest income quartileHospital complicationsHospital mortalityComplication ratePatient demographicsSurgical complicationsIndependent predictorsPrimary outcomeEGS conditionsMean ageInpatient Sample