2018
Changing prognosis of oral cancer: An analysis of survival and treatment between 1973 and 2014
Cheraghlou S, Schettino A, Zogg CK, Judson BL. Changing prognosis of oral cancer: An analysis of survival and treatment between 1973 and 2014. The Laryngoscope 2018, 128: 2762-2769. PMID: 30194691, DOI: 10.1002/lary.27315.Peer-Reviewed Original ResearchConceptsOral cavity cancerLate-stage diseaseAdjuvant therapyOral cancerEnd Results 9 registriesCox survival regressionHigher nodal yieldsNational Cancer DatabaseEarly-stage diseaseKaplan-Meier analysisRetrospective database analysisAnalysis of survivalAdjuvant chemoradiotherapyNodal yieldAdult patientsNeck dissectionRetrospective studyCancer DatabasePrognosisPatientsCancerDiseaseDatabase analysisSurvival regressionChemoradiotherapy
2014
Phosphoglycerate Dehydrogenase: Potential Therapeutic Target and Putative Metabolic Oncogene
Zogg CK. Phosphoglycerate Dehydrogenase: Potential Therapeutic Target and Putative Metabolic Oncogene. Journal Of Oncology 2014, 2014: 524101. PMID: 25574168, PMCID: PMC4276281, DOI: 10.1155/2014/524101.Peer-Reviewed Original ResearchRole of PHGDHPotential therapeutic targetMetabolic oncogeneTherapeutic targetEnzyme phosphoglycerate dehydrogenaseTumor suppressors/oncogenesClassic animal studiesPhosphoglycerate dehydrogenaseAnimal studiesWarburg effectMetabolic pathwaysRate-limiting stepOncogenePHGDHMetabolic explanationCancerCell preference