Brian Wojeck, MD, MPH
Assistant Professor of Medicine (Endocrinology)Cards
About
Research
Publications
2026
Transoral Neuromuscular Electrical Stimulation Therapy Adherence and Intensity Levels in Veterans with Mild OSA
Stepnowsky C, Zamora T, Velazquez Y, Schmickl C, Cervantes-Gameros C, Owens R, Wojeck B, Colvonen P, Nokes B. Transoral Neuromuscular Electrical Stimulation Therapy Adherence and Intensity Levels in Veterans with Mild OSA. SLEEP Advances 2026, zpag061. DOI: 10.1093/sleepadvances/zpag061.Peer-Reviewed Original ResearchObstructive sleep apneaMild obstructive sleep apneaRetrospective reviewVA San Diego Healthcare SystemStimulation intensity levelsPositive airway pressure adherenceAbstract Study ObjectivesWeek 1 to week 6Sleep apneaPhase 1Therapy adherenceAdherence definitionsWeek 6Study objectiveTherapyPatientsStimulation therapyStimulation intensityAdherenceWeeksDaysStimulationPhase 2Intensity levelsMinutesC75-17 Insomnia, Sleep Apnea, and Incidence of Pre-diabetes Among U.S. Military Veterans
Al Jumaily K, Gaffey A, Wojeck B, Zinchuk A. C75-17 Insomnia, Sleep Apnea, and Incidence of Pre-diabetes Among U.S. Military Veterans. American Journal Of Respiratory And Critical Care Medicine 2026, 212: aamag286.324. DOI: 10.1093/ajrccm/aamag286.324.Peer-Reviewed Original ResearchObstructive sleep apneaRetrospective cohort studySleep apneaPre-diabetesAssociated with future cardiovascular diseaseRisk of incident prediabetesBody mass index categoriesSleep disordersAssociated with impaired glucose regulationType 2 diabetes mellitusMultivariate Cox modelFuture cardiovascular diseaseIncidence of pre-diabetesCox proportional hazards modelsImpaired glucose regulationProgression to T2DMTime-to-event analysisModifiable risk factorsU.S. military veteransProportional hazards modelCardiometabolic comorbiditiesVeterans Health AdministrationHazard ratioBackground PrediabetesPublic health priority1029 Insomnia, Sleep Apnea and Incident Diabetes Among U.S. Military Veterans
Al Jumaily K, Gaffey A, Zinchuk A, Wojeck B. 1029 Insomnia, Sleep Apnea and Incident Diabetes Among U.S. Military Veterans. Sleep 2026, 49: a458-a458. DOI: 10.1093/sleep/zsag091.1028.Peer-Reviewed Original ResearchObstructive sleep apneaVeterans Health AdministrationMetabolic riskSleep apneaSleep disordersCohort studyIncident T2DMPredictor of incident T2DMRisk of new-onset T2DMAntihyperglycemic medication useType 2 diabetes mellitusElevated riskNew-onset T2DMEarly identificationCox proportional hazards modelsBody mass indexHigh-risk populationTime-varying exposureProportional hazards modelCommunity-based sampleMiddle-aged adultsSecondary data analysisU.S. military veteransIdentification of sleep disordersLaboratory valuesPerspective—weight loss, obstructive sleep apnea therapy, or both for cardiometabolic risk in obesity-related obstructive sleep apnea?
Nokes B, Wojeck B, Schmickl C. Perspective—weight loss, obstructive sleep apnea therapy, or both for cardiometabolic risk in obesity-related obstructive sleep apnea? Sleep 2026, zsag116. PMID: 42033315, DOI: 10.1093/sleep/zsag116.Peer-Reviewed Original ResearchComorbid obesityObesity-related obstructive sleep apneaObstructive sleep apnea therapyImpact of weight lossObstructive sleep apneaWeight loss medicationsSleep apnea therapyObesity pharmacotherapyOSA severitySleep apneaTreatment landscapeCardiometabolic riskClinical trialsFDA approvalOSAReal-world outcomesObesityWeight lossTrialsApneaTherapyPatientsPharmacotherapyMedicationFDA
2025
Obesity Medications Beyond Glucose Control and Weight Reduction: Updates on the Expanding Benefits, Clinical Challenges, and Future Directions
Ntelis S, Wojeck B. Obesity Medications Beyond Glucose Control and Weight Reduction: Updates on the Expanding Benefits, Clinical Challenges, and Future Directions. Current Hypertension Reports 2025, 28: 5. PMID: 41460420, DOI: 10.1007/s11906-025-01349-0.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsClinical benefitClinical effectsLow riskRisk of atherosclerotic cardiovascular eventsObstructive sleep apneaPreserved Ejection FractionInitiation of treatmentDiabetic kidney diseaseAtherosclerotic cardiovascular eventsWeight reductionSleep apneaEjection fractionObesity medicationsReceptor agonistsClinical outcomesIncretin therapiesAdverse eventsHeart failureCardiovascular eventsClinical challengeClinical trialsKidney diseaseLiver diseaseGlycemic controlObesity managementThe impact of obesity on upper airway anatomy as assessed by magnetic resonance imaging and obstructive sleep apnea endotypic traits
Nokes B, Schueler A, Darquenne C, Schmickl C, Wojeck B, Moore S, Deyoung P, McGinnis L, Theilmann R, Gruenberg E, Grunvald E, Holloway B, Alex R, Sands S, Colvonen P, Owens R, Malhotra A. The impact of obesity on upper airway anatomy as assessed by magnetic resonance imaging and obstructive sleep apnea endotypic traits. Frontiers In Physiology 2025, 16: 1648767. PMID: 41103297, PMCID: PMC12521235, DOI: 10.3389/fphys.2025.1648767.Peer-Reviewed Original ResearchAssociated with apnea-hypopnea indexObstructive sleep apneaUpper airway anatomyUpper airway magnetic resonance imagingMagnetic resonance imagingAirway anatomyEndotypic traitsSleeve gastrectomyResonance imagingObstructive Sleep Apnea EndotypesObstructive sleep apnea outcomesObstructive sleep apnea treatmentImpact of weight lossApnea-hypopnea indexUpper airway lengthBariatric surgery clinicWeight lossImpact of obesityHypopnea indexHypoxic burdenResearch polysomnographySleep apneaSurgery clinicPolysomnographyObesity managementAssociation Between Sleep-Related Leg Movements and Diabetes Prevalence: A Cohort Study From the United States
Ding Q, Xie Y, Koo B, Hass Z, Wojeck B, Sico J, Murray-Kolb L, Bravata D, Zinchuk A. Association Between Sleep-Related Leg Movements and Diabetes Prevalence: A Cohort Study From the United States. Cureus 2025, 17: e84701. PMID: 40557002, PMCID: PMC12185253, DOI: 10.7759/cureus.84701.Peer-Reviewed Original ResearchNational Health and Nutrition Examination SurveyShort sleep durationSleep durationDiabetes prevalenceHealth and Nutrition Examination SurveyNational population-based cohort studyNon-Hispanic white individualsCohort studyPopulation-based cohort studyWeighted logistic regression modelsOdds of diabetesNutrition Examination SurveyUS adult populationPrevalence of diabetesRisk of diabetesLeg movementsDiabetes mellitusLogistic regression modelsDM prevalenceExamination SurveyCardiometabolic healthUnited StatesWhite individualsAdult populationPotential mediators
2024
Understanding the impact of night-to-night sleep variations on glucose regulation in healthy young adults: Insights from Ng et al. (2024)
Ding Q, Wojeck B, Zinchuk A. Understanding the impact of night-to-night sleep variations on glucose regulation in healthy young adults: Insights from Ng et al. (2024). Sleep 2024, 48: zsae253. PMID: 39460669, PMCID: PMC11807883, DOI: 10.1093/sleep/zsae253.Commentaries, Editorials and LettersEffect of obesity on sleep apnea pathogenesis differs in women versus men: multiple mediation analyses in the retrospective SNOOzzzE cohort
Nokes B, Orr J, White S, Luu S, Chen Z, Alex R, Sands S, Wojeck B, Owens R, Malhotra A, Schmickl C. Effect of obesity on sleep apnea pathogenesis differs in women versus men: multiple mediation analyses in the retrospective SNOOzzzE cohort. Journal Of Applied Physiology 2024, 136: 1516-1525. PMID: 38660729, PMCID: PMC11368527, DOI: 10.1152/japplphysiol.00925.2023.Peer-Reviewed Original ResearchApnea-hypopnea indexObstructive sleep apneaBody mass indexEffect of body mass indexCirculatory delayArousal thresholdAssociated with apnea-hypopnea indexObstructive sleep apnea risk factorsObstructive Sleep Apnea EndotypesIn-laboratory polysomnographyUpper airway collapseEvents per hourHigh arousal thresholdsEffect of obesityHypopnea indexOSA pathogenesisSleep apneaConsecutive adultsSleep clinicEndotypic traitsAirway collapseMass indexPathogenesis differencesRisk factorsPolysomnography signalsChapter 35 Diseases of the pituitary gland
Wojeck B, Kryger M. Chapter 35 Diseases of the pituitary gland. 2024, 374-378.e1. DOI: 10.1016/b978-0-323-65403-6.00044-5.Chapters
Clinical Care
Overview
Brian Wojeck, MD, MPH, is an assistant professor at Yale School of Medicine (YSM) in the Section of Endocrinology. He received his medical degree from University of Arizona and his master of public health from Emory University. He completed his internal medicine residency at Mayo Clinic and subspecialty fellowships in sleep medicine and endocrinology at YSM. He has additional training in obesity medicine and is a weight management specialist.
Dr. Wojeck's clinical and research focus is the comprehensive management of the interrelated disease processes of diabetes, obesity, and sleep disorders.
Clinical Specialties
Endocrinology; Sleep Medicine; Obesity Medicine
Fact Sheets
Sleep Study
Learn More on Yale MedicineSleep Apnea
Learn More on Yale MedicinePediatric Obstructive Sleep Apnea
Learn More on Yale MedicineSurgeries for Upper Aero-Digestive Tract
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Board Certifications
Obesity Medicine
- Certification Organization
- AB of Obesity Medicine
- Original Certification Date
- 2020
Yale Medicine News
News
News
- October 07, 2025
Uncovering Hidden Risk Factors: Sleep-Related Leg Movements and Diabetes
- January 27, 2025
Drawing Connections Between Diabetes, Obesity, and Sleep
- October 18, 2022
Yale Endocrinology Obesity Medicine: Approaching Obesity as a Complex, Chronic Disease
- July 27, 2022
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Nov 202620Friday
Everyone Bubu Banini, MD, PhD - Jorge Moreno, MD - John Morton, MD, MPH, MHA, BS, FACS, FASMBS - Brian Wojeck, MD, MPH