2000
Kinetics and control of oxidative phosphorylation in rat liver mitochondria after chronic ethanol feeding.
Marcinkeviciute A, Mildaziene V, Crumm S, Demin O, Hoek J, Kholodenko B. Kinetics and control of oxidative phosphorylation in rat liver mitochondria after chronic ethanol feeding. Biochemical Journal 2000, 349: 519-26. PMID: 10880351, PMCID: PMC1221175, DOI: 10.1042/0264-6021:3490519.Peer-Reviewed Original ResearchConceptsOxidative phosphorylationRespiratory fluxMitochondrial proton leakRat liver mitochondriaMitochondrial oxidative phosphorylationCytochrome c oxidaseMitochondrial energy metabolismATP synthaseLiver mitochondriaProton leakC oxidaseProtonmotive forceState 3Blocks of reactionsPhosphorylationEnergy metabolismMitochondriaMitochondrial malfunctioningRespiration rateRespiratory activityRespiratory subsystemIndividual functional unitsFunctional units
1995
Calcium Indirectly Increases the Control Exerted by the Adenine Nucleotide Translocator over 2-Oxoglutarate Oxidation in Rat Heart Mitochondria
Mildaziene V, Baniene R, Nauciene Z, Bakker B, Brown G, Westerhoff H, Kholodenko B. Calcium Indirectly Increases the Control Exerted by the Adenine Nucleotide Translocator over 2-Oxoglutarate Oxidation in Rat Heart Mitochondria. Archives Of Biochemistry And Biophysics 1995, 324: 130-134. PMID: 7503547, DOI: 10.1006/abbi.1995.9918.Peer-Reviewed Original Research
1991
Regulation of the heart mitochondrial respiration rate. Comparison of oxidation of succinate and NAD-dependent substrates.
Kholodenko B, Millazhane V, Borutaĭte V, Ivanovene L, Iuodkaĭte R, Katiliute Z, Toleĭkis A. Regulation of the heart mitochondrial respiration rate. Comparison of oxidation of succinate and NAD-dependent substrates. Биохимия 1991, 56: 1420-8. PMID: 1782265.Peer-Reviewed Original ResearchConceptsAdenine nucleotide translocatorNAD-dependent substratesSame relative rateInner mitochondrial membraneProton leakageMitochondrial respiration rateState 4Mitochondrial processesExtramitochondrial adenine nucleotidesMitochondrial membraneState 3Nucleotide translocatorRegulation of respirationRate of respirationSuccinate dehydrogenaseSuccinate oxidationHeart mitochondriaMembrane potentialRespirationRelative ratesRespiration rateMaximal rateRegulationControl of respirationControl coefficients
1988
The role of adenine nucleotide translocator in the regulation of oxidative phosphorylation in heart mitochondria.
Kholodenko B, Zhilinskene V, Borutaĭte V, Ivanovene L, Toleĭkis A. The role of adenine nucleotide translocator in the regulation of oxidative phosphorylation in heart mitochondria. Биохимия 1988, 53: 1009-12. PMID: 2846076.Peer-Reviewed Original ResearchConceptsAdenine nucleotide translocaseOxidative phosphorylationNucleotide translocaseADP/ATP translocaseHeart mitochondriaATP translocaseTitration of respirationTranslocaseRegulatory rolePhosphorylationRabbit heart mitochondriaMitochondriaRespiration rateRole of adenineRegulationRespirationKey roleState 3TranslocatorRoleCarboxyatractylosideControl coefficientsADP