Regulation of the heart mitochondrial respiration rate. Comparison of oxidation of succinate and NAD-dependent substrates.
Kholodenko B, Millazhane V, Borutaĭte V, Ivanovene L, Iuodkaĭte R, Katiliute Z, Toleĭkis A. Regulation of the heart mitochondrial respiration rate. Comparison of oxidation of succinate and NAD-dependent substrates. Биохимия 1991, 56: 1420-8. PMID: 1782265.Peer-Reviewed Original ResearchMeSH KeywordsAdenine NucleotidesAnimalsCreatine KinaseFlavin-Adenine DinucleotideMitochondria, HeartNADOxidation-ReductionOxygenRabbitsSubstrate SpecificitySuccinatesSuccinic AcidConceptsAdenine nucleotide translocatorNAD-dependent substratesSame relative rateInner mitochondrial membraneProton leakageMitochondrial respiration rateState 4Mitochondrial processesExtramitochondrial adenine nucleotidesMitochondrial membraneState 3Nucleotide translocatorRegulation of respirationRate of respirationSuccinate dehydrogenaseSuccinate oxidationHeart mitochondriaMembrane potentialRespirationRelative ratesRespiration rateMaximal rateRegulationControl of respirationControl coefficients