The function of ATP/ADP translocator in the regulation of mitochondrial respiration during development of heart ischemic injury
Borutaité V, Mildažiene V, Katiliūté Z, Kholodenko B, Toleikis A. The function of ATP/ADP translocator in the regulation of mitochondrial respiration during development of heart ischemic injury. Biochimica Et Biophysica Acta 1993, 1142: 175-180. PMID: 8457582, DOI: 10.1016/0005-2728(93)90099-2.Peer-Reviewed Original ResearchConceptsATP/ADP translocatorHeart ischemic injuryNormal mitochondriaInhibitor titration studiesRate of succinateIschemic injuryMin ischemiaMitochondrial respiratory rateRespiratory rateOxidative phosphorylationTranslocatorMitochondrial respirationMalate oxidationMitochondriaState 3Heart mitochondriaTotal ischemiaControl coefficientsIschemiaState 4RegulationIschemic mitochondriaInjuryPhosphorylationMaximal rate