2000
Anatomic basis of sequence‐dependent predictability exhibited by nigral dopamine neuron firing patterns
Hoffman R, Shi W, Bunney B. Anatomic basis of sequence‐dependent predictability exhibited by nigral dopamine neuron firing patterns. Synapse 2000, 39: 133-138. PMID: 11180500, DOI: 10.1002/1098-2396(200102)39:2<133::aid-syn4>3.0.co;2-k.Peer-Reviewed Original Research
1997
Dopamine-cell depolarization block as a model for the therapeutic actions of antipsychotic drugs
Grace A, Bunney B, Moore H, Todd C. Dopamine-cell depolarization block as a model for the therapeutic actions of antipsychotic drugs. Trends In Neurosciences 1997, 20: 31-37. PMID: 9004417, DOI: 10.1016/s0166-2236(96)10064-3.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntipsychotic AgentsDopamineDopamine AgonistsMembrane PotentialsModels, NeurologicalConceptsDepolarization blockAntipsychotic drugsDopamine systemNigrostriatal dopamine systemWeeks of treatmentExtrapyramidal side effectsAntipsychotic drug efficacyDopamine receptor antagonistDrug treatment resultsMesolimbic dopamine neuronsTreatment of schizophreniaDopamine neuron firingReceptor blockadeDopamine neuronsTherapeutic impactSide effectsClinical actionsDrug AdministrationTherapeutic efficacyTreatment resultsDrug efficacyTherapeutic actionPotential mechanismsDrugsEfficacy
1995
Nonlinear sequence-dependent structure of nigral dopamine neuron interspike interval firing patterns
Hoffman R, Shi W, Bunney B. Nonlinear sequence-dependent structure of nigral dopamine neuron interspike interval firing patterns. Biophysical Journal 1995, 69: 128-137. PMID: 7669889, PMCID: PMC1236231, DOI: 10.1016/s0006-3495(95)79882-4.Peer-Reviewed Original ResearchConceptsNonlinear deterministic structureDeterministic structureNumber of degreesDopamine neuronsDynamical analysisEffect of nonstationarityRandom processFiring patternsNigral dopamine neuronsRat substantia nigraSubstantia nigraSynaptic inputsISI sequencesNeuron responsesTime seriesNeural circuit interactionsSequence-dependent structureNeuronsFiring modesCircuit interactionsOverall predictabilityNonstationarity
1991
Midbrain dopamine system electrophysiological functioning: A review and new hypothesis
Bunney B, Chiodo L, Grace A. Midbrain dopamine system electrophysiological functioning: A review and new hypothesis. Synapse 1991, 9: 79-94. PMID: 1821487, DOI: 10.1002/syn.890090202.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell CommunicationDopamineElectrophysiologyFeedbackHumansMesencephalonModels, NeurologicalNervous System DiseasesNeurons