GABAergic polygenic risk for cocaine use disorder is negatively correlated with precuneus activity during cognitive control in African American individuals
Yang BZ, Balodis IM, Kober H, Worhunsky PD, Lacadie CM, Gelernter J, Potenza MN. GABAergic polygenic risk for cocaine use disorder is negatively correlated with precuneus activity during cognitive control in African American individuals. Addictive Behaviors 2020, 114: 106695. PMID: 33153773, PMCID: PMC8299472, DOI: 10.1016/j.addbeh.2020.106695.Peer-Reviewed Original ResearchTubulin Polymerization Promoting Protein (TPPP) gene methylation and corpus callosum measures in maltreated children
de Araújo CM, Hudziak J, Crocetti D, Wymbs NF, Montalvo-Ortiz JL, Orr C, Albaugh MD, Althoff RR, O'Loughlin K, Holbrook H, Garavan H, Yang BZ, Mostofsky S, Jackowski A, Lee RS, Gelernter J, Kaufman J. Tubulin Polymerization Promoting Protein (TPPP) gene methylation and corpus callosum measures in maltreated children. Psychiatry Research Neuroimaging 2020, 298: 111058. PMID: 32120304, PMCID: PMC11079625, DOI: 10.1016/j.pscychresns.2020.111058.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildChild AbuseCohort StudiesCorpus CallosumDNA MethylationFemaleHumansMagnetic Resonance ImagingMaleNerve Tissue ProteinsConceptsStress-related psychiatric disordersCorpus callosum measuresFractional anisotropyPsychiatric disordersTrauma experiencesWhite matter tractsChild trauma experiencesBrain changesLarger studyRelevant covariatesAtlas-based approachSplenium fractional anisotropyDNA specimensMultiple comparisonsGene methylationDisordersChildrenCurrent study