2021
Treatment outcomes in individuals diagnosed with comorbid opioid use disorder and Posttraumatic stress disorder: A review
Meshberg-Cohen S, MacLean R, Martin A, Sofuoglu M, Petrakis IL. Treatment outcomes in individuals diagnosed with comorbid opioid use disorder and Posttraumatic stress disorder: A review. Addictive Behaviors 2021, 122: 107026. PMID: 34182307, DOI: 10.1016/j.addbeh.2021.107026.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderComorbid opioid use disorderStress disorderImpact of PTSDPresence of PTSDComorbid posttraumatic stress disorderUse disordersOpioid use disorderMultiple mental health problemsMental health problemsPTSD treatmentComparison participantsTreatment outcomesPTSD diagnosisPsychosocial problemsStandardized assessmentConcurrent diagnosisPsychiatric conditionsMedical record diagnosisDrug useIndividualsDisordersPublic health emergencyRecord diagnosisInclusion criteria
2014
Effects of Δ9-tetrahydrocannabinol in individuals with a familial vulnerability to alcoholism
Ranganathan M, Sewell RA, Carbuto M, Elander J, Schnakenberg A, Radhakrishnan R, Pittman B, D’Souza D. Effects of Δ9-tetrahydrocannabinol in individuals with a familial vulnerability to alcoholism. Psychopharmacology 2014, 231: 2385-2393. PMID: 24424782, DOI: 10.1007/s00213-013-3402-4.Peer-Reviewed Original ResearchConceptsPerceptual alterationsRewarding effectsSubjective effectsAlcohol-related behaviorsΔ9-THCExecutive functionEffects of alcoholSpatial memoryMemory impairmentCounterbalanced orderAlcohol problemsFamilial vulnerabilityCannabinoid receptor functionΔ9-tetrahydrocannabinolCannabinoid Δ9-tetrahydrocannabinolFirst human studyDouble-blind conditionsCB1R functionOutcome measuresIndividualsMemoryMeasuresAlcoholismSecondary outcome measuresHuman studies