2023
Analysis of the impact of eliminating bolus 5-fluorouracil in metastatic colorectal cancer.
Peng C, Saffo S, Shusterman M, Becker D, Berlin J, Oberstein P, Nagar A, Yu S. Analysis of the impact of eliminating bolus 5-fluorouracil in metastatic colorectal cancer. Journal Of Clinical Oncology 2023, 41: 59-59. DOI: 10.1200/jco.2023.41.4_suppl.59.Peer-Reviewed Original ResearchMetastatic colorectal cancerOverall survivalECOG scoreColorectal cancerUnivariable Cox proportional hazards modelsFirst-line treatment regimensCox proportional hazards modelHigher ECOG scoreHigh-risk comorbiditiesRole of bolusMulticenter cohort studyOverall survival benefitRisk of deathLimited functional statusCombination drug regimenProportional hazards modelUse of bolusPropensity-score matchingAdjuvant settingBaseline creatinineFlatiron HealthMedian followCohort studyCreatinine levelsDrug regimen
2021
Prevalence of Advanced Colorectal Neoplasia in Veterans
Imperiale TF, Daggy JK, Imler TD, Sherer EA, Kahi CJ, Larson J, Cardwell J, Johnson CS, Ahnen DJ, Antaki F, Ashley C, Baffy G, Dominitz JA, Hou J, Korsten MA, Nagar A, Promrat K, Robertson DJ, Saini S, Shergill A, Smalley WE. Prevalence of Advanced Colorectal Neoplasia in Veterans. Journal Of Clinical Gastroenterology 2021, 55: 876-883. PMID: 34049372, DOI: 10.1097/mcg.0000000000001402.Peer-Reviewed Original ResearchConceptsAdvanced neoplasiaProximal colorectal cancerColorectal cancerVeterans Affairs Medical CenterProximal advanced neoplasiaAdvanced colorectal neoplasiaCross-sectional studyIndependent effectsHigh overall prevalenceRace/ethnicityCRC prevalenceColorectal neoplasiaCRC riskOverall prevalenceMedical CenterDiagnostic subgroupsLogistic regressionPrevalenceAgeVeteransWomenColonoscopyNeoplasiaRiskAdvanced findings