Angelo Porciuncula
Associate Research ScientistCards
About
Research
Publications
2026
Conventional type-1 DC density is associated with checkpoint inhibitor response across multiple types of cancer
Lopez-Janeiro A, González-Gomariz J, Issa F, Hester J, Porciuncula A, Teijeira A, Luri-Rey C, Ruiz-Guillamon D, Perez-Gracia J, Perez-Ruiz E, Barragan I, Martín-Algarra S, Sanmamed M, Ortego I, Rodriguez-Ruiz M, Alexandru R, Rodriguez I, Arrieta-Aranzueque S, Rimm D, Aung T, Schalper K, de Andrea C, Melero I. Conventional type-1 DC density is associated with checkpoint inhibitor response across multiple types of cancer. Journal Of Clinical Investigation 2026, 136: e200987. PMID: 42065248, PMCID: PMC13132367, DOI: 10.1172/jci200987.Peer-Reviewed Original Research
2025
Selective STING Activation in Intratumoral Myeloid Cells via CCR2-Directed Antibody–Drug Conjugate TAK-500
Appleman V, Matsuda A, Ganno M, Zhang D, Rosentrater E, Lopez A, Porciuncula A, Hatten T, Christensen C, Merrigan S, Lee H, Lee M, Wang C, Dong L, Huang J, Iartchouk N, Wang J, Xu H, Yoneyama T, Piatkov K, Haridas S, Harbison C, Gregory R, Parent A, Lineberry N, Arendt C, Schalper K, Abu-Yousif A. Selective STING Activation in Intratumoral Myeloid Cells via CCR2-Directed Antibody–Drug Conjugate TAK-500. Cancer Immunology Research 2025, 13: 661-679. PMID: 39918395, PMCID: PMC12046323, DOI: 10.1158/2326-6066.cir-24-0103.Peer-Reviewed Original Research