2024
Multicenter validation of automated detection of paramagnetic rim lesions on brain MRI in multiple sclerosis
Chen L, Ren Z, Clark K, Lou C, Liu F, Cao Q, Manning A, Martin M, Luskin E, O'Donnell C, Azevedo C, Calabresi P, Freeman L, Henry R, Longbrake E, Oh J, Papinutto N, Bilello M, Song J, Kaisey M, Sicotte N, Reich D, Solomon A, Ontaneda D, Sati P, Absinta M, Schindler M, Shinohara R, Cooperative T. Multicenter validation of automated detection of paramagnetic rim lesions on brain MRI in multiple sclerosis. Journal Of Neuroimaging 2024, 34: 750-757. PMID: 39410780, DOI: 10.1111/jon.13242.Peer-Reviewed Original ResearchParamagnetic rim lesionsArea under the curveRim lesionsMultiple sclerosisPrognosis of MSBiomarkers of chronic inflammationWhite matter lesionsMulticenter settingMulticenter studyMulticenter validationChronic inflammationBrain MRIClinical trialsIdentified lesionsMulticenterMS diagnosisLesionsParamagnetic rimAutomated segmentation methodMRIMRI biomarkersMulticenter datasetDiagnosisSclerosisTeam of trained raters
2022
The Sit-to-Stand Transition as a Biomarker for Impairment: Comparison of Instrumented 30-Second Chair Stand Test and Daily Life Transitions in Multiple Sclerosis
Tulipani L, Meyer B, Fox S, Solomon A, Mcginnis R. The Sit-to-Stand Transition as a Biomarker for Impairment: Comparison of Instrumented 30-Second Chair Stand Test and Daily Life Transitions in Multiple Sclerosis. IEEE Transactions On Neural Systems And Rehabilitation Engineering 2022, 30: 1213-1222. PMID: 35468063, PMCID: PMC9204833, DOI: 10.1109/tnsre.2022.3169962.Peer-Reviewed Original ResearchConceptsSensory impairmentInvestigate impairmentsDaily lifeLevel of clinical disabilityPerformance metricsStructured tasksImpairmentPyramidal impairmentSub scoresMultiple sclerosisDaily life monitoringDichotomize participantsSit-stand transitionsClinical disabilityClassification performanceTaskWearable sensorsSupervised settingChest featuresFaller classificationDeficitsLife monitoringLow fall riskArea under the curveFunctional assessment