2024
Implications of Surgical Infection on Surgical and Hospital Outcomes after Spine Surgery: A NSQIP Study of 410,930 Patients
Elsamadicy A, Serrato P, Sadeghzadeh S, Dietz N, Lo S, Sciubba D. Implications of Surgical Infection on Surgical and Hospital Outcomes after Spine Surgery: A NSQIP Study of 410,930 Patients. Clinical Neurology And Neurosurgery 2024, 108505. DOI: 10.1016/j.clineuro.2024.108505.Peer-Reviewed Original ResearchExtended hospital length of stayNon-routine dischargeLength of staySurgical infectionsHospital length of stayExtended hospital lengthRetrospective cohort studySpine surgeryAdverse eventsStudy Design Retrospective cohort studyCohort studyPredictors of adverse eventsMultivariate logistic regression analysisRate of adverse eventsProlonged length of stayACS NSQIP databaseRisk of complicationsPostoperative adverse eventsHealthcare resource utilizationICD-9/10 codesLogistic regression analysisNon-home dischargeNSQIP studiesDesign Retrospective cohort studyMean BMIImpact of Depression on Postoperative Medical and Surgical Outcomes in Spine Surgeries: A Systematic Review and Meta-Analysis
Aghajanian S, Shafiee A, Athar M, Mohammadifard F, Goodarzi S, Esmailpur F, Elsamadicy A. Impact of Depression on Postoperative Medical and Surgical Outcomes in Spine Surgeries: A Systematic Review and Meta-Analysis. Journal Of Clinical Medicine 2024, 13: 3247. PMID: 38892958, PMCID: PMC11172961, DOI: 10.3390/jcm13113247.Peer-Reviewed Original ResearchNon-routine dischargeSpine surgerySurgical complicationsSurgical outcomesStatistically significant higher rateUrinary tract infectionSurgical site infectionDeep vein thrombosisLength of hospitalizationSystematic reviewNon-depressed controlsSignificantly higher ratesUrinary retentionPostoperative medicationTract infectionsPostoperative outcomesPulmonary embolismSite infectionSpinal surgeryVein thrombosisImpact of depressionPooled analysisDepressed patientsHematoma formationHospital lengthEfficacy and utility of antifibrinolytics in pediatric spine surgery: a systematic review and network meta-analysis
Aghajanian S, Mohammadifard F, Kohandel Gargari O, Naeimi A, Bahadorimonfared A, Elsamadicy A. Efficacy and utility of antifibrinolytics in pediatric spine surgery: a systematic review and network meta-analysis. Neurosurgical Review 2024, 47: 177. PMID: 38644447, DOI: 10.1007/s10143-024-02424-x.Peer-Reviewed Original ResearchConceptsNetwork meta-analysisRate of complicationsBlood lossSpine surgeryEpsilon-aminocaproic acidMeta-analysisTranexamic acidEfficacy of antifibrinolyticsPediatric spine surgeryPerioperative blood lossReduce blood lossStandardized outcome dataRandomized clinical trialsStandard of carePerioperative bleedingTransfusion volumeTransfusion rateAntifibrinolytic agentsMassive transfusionPediatric patientsSafety profilePediatric surgeryProbability of efficacyAntifibrinolyticsClinical trials
2023
Academic career progression in AANS/CNS Spine Section award recipients
Elsamadicy A, Sherman J, Craft S, Virk M, Elder B, Bonfield C, Snyder L, Ray W, Jones K, Ryu W. Academic career progression in AANS/CNS Spine Section award recipients. Journal Of Neurosurgery Spine 2023, 1-8. DOI: 10.3171/2023.7.spine23259.Peer-Reviewed Original ResearchConceptsAcademic medical centerPeer-reviewed journalsMedical CenterPeer-reviewed publicationsMean numberPrincipal investigatorMean h-indexAANS/CNS SectionNational InstituteFederal research fundingPeripheral nervesCNS SectionSpine surgeryOutstanding abstractsPrior recipientsMedical Research ProgramSubspecialty focusHealth fundingRecipientsAppointment statusNeurological SurgeonsPublication rateOne-thirdFaculty appointmentsProgression
2022
Utilization of Machine Learning to Model Important Features of 30-day Readmissions following Surgery for Metastatic Spinal Column Tumors: The Influence of Frailty
Elsamadicy A, Koo A, Reeves B, Cross J, Hersh A, Hengartner A, Karhade A, Pennington Z, Akinduro O, Lo S, Gokaslan Z, Shin J, Mendel E, Sciubba D. Utilization of Machine Learning to Model Important Features of 30-day Readmissions following Surgery for Metastatic Spinal Column Tumors: The Influence of Frailty. Global Spine Journal 2022, 14: 1227-1237. PMID: 36318478, PMCID: PMC11289550, DOI: 10.1177/21925682221138053.Peer-Reviewed Original ResearchHospital Frailty Risk ScoreSpinal column tumorsFrailty Risk ScoreInfluence of frailtySpinal column metastasesProportion of patientsRetrospective cohort studyNationwide Readmissions DatabaseRisk of readmissionMultivariate regression analysisIntermediate frailtyAdult patientsCohort studyIndependent predictorsSurgical interventionSpine surgeryReadmissionPatient readmissionRisk scorePatientsFrailtySurgeryCohortTumorsRegression analysis
2021
Effects of preoperative nutritional status on complications and readmissions after posterior lumbar decompression and fusion for spondylolisthesis: A propensity-score analysis
Elsamadicy AA, Havlik J, Reeves BC, Koo AB, Sherman J, Lo SL, Shin JH, Sciubba DM. Effects of preoperative nutritional status on complications and readmissions after posterior lumbar decompression and fusion for spondylolisthesis: A propensity-score analysis. Clinical Neurology And Neurosurgery 2021, 211: 107017. PMID: 34781222, DOI: 10.1016/j.clineuro.2021.107017.Peer-Reviewed Original ResearchConceptsUnplanned readmissionAdverse eventsSpine surgerySurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseOccurrence of AEsPreoperative serum albumin levelQuality Improvement Program databaseMultivariate logistic regression analysisPosterior lumbar decompressionPreoperative nutritional statusHigh rateImprovement Program databaseRetrospective cohort studySerum albumin levelSignificant independent predictorsEffects of malnutritionLogistic regression analysisPropensity score analysisPropensity-score matchingMalnourished cohortMalnourished patientsPerioperative complicationsPostoperative complicationsLumbar decompressionImpact of race on outcomes and healthcare utilization following spinal fusion for adolescent idiopathic scoliosis
Elsamadicy AA, Koo AB, David WB, Freedman IG, Kundishora AJ, Hong CS, Sarkozy M, Sciubba DM, Kahle KT, DiLuna M. Impact of race on outcomes and healthcare utilization following spinal fusion for adolescent idiopathic scoliosis. Clinical Neurology And Neurosurgery 2021, 206: 106634. PMID: 33979695, DOI: 10.1016/j.clineuro.2021.106634.Peer-Reviewed Original ResearchConceptsPosterior spinal fusionPostoperative complicationsAdolescent idiopathic scoliosisPatient demographicsIdiopathic scoliosisAdolescent patientsSpine surgerySpinal fusionBlack cohortBaseline patient demographicsRate of complicationsMajority of patientsPosterior spine surgeryPosterior spinal surgeryMedian total costBaseline comorbiditiesHospital stayDischarge dispositionInpatient managementPostoperative outcomesBlood transfusionPrimary outcomeFemale patientsHealthcare utilizationHispanic patientsCost and Health Care Resource Utilization Differences After Spine Surgery for Bony Spine versus Primary Intradural Spine Tumors
Elsamadicy AA, Koo AB, Reeves BC, Freedman IG, Pennington Z, David WB, Ehresman J, Hengartner A, Laurans M, Kolb L, Shin JH, Sciubba DM. Cost and Health Care Resource Utilization Differences After Spine Surgery for Bony Spine versus Primary Intradural Spine Tumors. World Neurosurgery 2021, 151: e286-e298. PMID: 33866030, DOI: 10.1016/j.wneu.2021.04.015.Peer-Reviewed Original ResearchConceptsLength of stayPrimary intradural spinal tumorsIntradural spinal tumorsSpine tumorsSpine surgeryPerioperative complicationsSpinal tumorsNational Inpatient Sample databaseMultivariable logistic regression analysisStepwise multivariable logistic regression analysisBackward stepwise multivariable logistic regression analysisIntradural spinal neoplasmsIntradural spine tumorsRetrospective cohort studyLogistic regression analysisHealth care resourcesMore comorbiditiesAdult patientsCohort studyDischarge dispositionIntraoperative variablesPatient demographicsComplication rateHospital admissionIndependent predictors
2020
Thirty- and 90-day Readmissions After Spinal Surgery for Spine Metastases
Elsamadicy AA, Koo AB, David WB, Zogg CK, Kundishora AJ, Hong CS, Kuzmik GA, Gorrepati R, Coutinho PO, Kolb L, Laurans M, Abbed K. Thirty- and 90-day Readmissions After Spinal Surgery for Spine Metastases. Spine 2020, 46: 828-835. PMID: 33394977, PMCID: PMC8278805, DOI: 10.1097/brs.0000000000003907.Peer-Reviewed Original ResearchConceptsSpine metastasesGenitourinary complicationsPostoperative infectionSpine surgeryRheumatoid arthritis/collagen vascular diseasesAcute post-hemorrhagic anemiaCollagen vascular diseaseRetrospective cohort studyUnplanned hospital readmissionNationwide Readmissions DatabasePatient-level factorsVulnerable patient groupSurgical treatment interventionMultivariate regression analysisFusion spine surgeryInpatient complicationsFrequent readmissionsUnplanned readmissionCohort studyRenal failureClinical factorsHospital readmissionSurgery typePatient groupVascular diseaseScoring System to Triage Patients for Spine Surgery in the Setting of Limited Resources
Sciubba D, Ehresman J, Pennington Z, Lubelski D, Feghali J, Bydon A, Chou D, Elder B, Elsamadicy A, Goodwin M, Goodwin C, Harrop J, Huq S, Klineberg E, Laufer I, Lo S, Neumaan B, Passias P, Protopsaltis T, Shin J, Theodore N, Witham T, Benzel E. Scoring System to Triage Patients for Spine Surgery in the Setting of Limited Resources. Neurosurgery 2020, 67: nyaa447_684. PMCID: PMC7717415, DOI: 10.1093/neuros/nyaa447_684.Peer-Reviewed Original ResearchScoring systemSpine surgerySurgical casesElective spine surgery patientsFellowship-trained spine surgeonsElective spine surgeryPatient medical comorbiditiesSpine surgery patientsPost-operative complicationsSpine surgery casesLocal disease burdenFinal scoring systemAcademic medical centerElective surgical casesResource-limited settingsWeb-based calculatorHospital courseMedical comorbiditiesDischarge dispositionNeurological statusSurgery patientsDisease burdenSurgery casesMedical CenterSpine surgeonsScoring System to Triage Patients for Spine Surgery in the Setting of Limited Resources: Application to the Coronavirus Disease 2019 (COVID-19) Pandemic and Beyond
Sciubba DM, Ehresman J, Pennington Z, Lubelski D, Feghali J, Bydon A, Chou D, Elder BD, Elsamadicy AA, Goodwin CR, Goodwin ML, Harrop J, Klineberg EO, Laufer I, Lo SL, Neuman BJ, Passias PG, Protopsaltis T, Shin JH, Theodore N, Witham TF, Benzel EC. Scoring System to Triage Patients for Spine Surgery in the Setting of Limited Resources: Application to the Coronavirus Disease 2019 (COVID-19) Pandemic and Beyond. World Neurosurgery 2020, 140: e373-e380. PMID: 32479913, PMCID: PMC7256646, DOI: 10.1016/j.wneu.2020.05.233.Peer-Reviewed Original ResearchConceptsElective spine surgeryCoronavirus disease 2019 (COVID-19) pandemicDisease 2019 pandemicSpine surgeryScoring systemSurgical casesFellowship-trained spine surgeonsPatient medical comorbiditiesSpine surgery casesLocal disease burdenFinal scoring systemAcademic medical centerElective surgical casesResource-limited settingsWeb-based calculatorHospital courseMedical comorbiditiesPostoperative complicationsDischarge dispositionNeurologic statusDisease burdenSurgery casesMedical CenterSpine surgeonsSpine stability
2019
Rate of instrumentation changes on postoperative and follow-up radiographs after primary complex spinal fusion (five or more levels) for adult deformity correction.
Elsamadicy AA, Lubkin DT, Sergesketter AR, Adil SM, Charalambous LT, Drysdale N, Williamson T, Camara-Quintana J, Abd-El-Barr MM, Goodwin CR, Karikari IO. Rate of instrumentation changes on postoperative and follow-up radiographs after primary complex spinal fusion (five or more levels) for adult deformity correction. Journal Of Neurosurgery Spine 2019, 30: 376-381. PMID: 30641841, DOI: 10.3171/2018.9.spine18686.Peer-Reviewed Original ResearchConceptsPrimary complex spinal fusionComplex spinal fusionSpinal fusionSpine surgeryDeformity correctionAdult deformity correctionCost-conscious healthcareMethodsThe medical recordsPostoperative complication rateMean lengthBody mass indexFollow-up radiographsRevision of surgeryComplex spine surgeryMajor academic institutionHospital stayAdult patientsComplication ratePatient demographicsReadmission ratesBlood lossPrimary outcomeMass indexEarly radiographsPostoperative radiographs
2018
Independent Associations With 30- and 90-Day Unplanned Readmissions After Elective Lumbar Spine Surgery: A National Trend Analysis of 144 123 Patients.
Elsamadicy AA, Ren X, Kemeny H, Charalambous L, Sergesketter AR, Rahimpour S, Williamson T, Goodwin CR, Abd-El-Barr MM, Gottfried ON, Xie J, Lad SP. Independent Associations With 30- and 90-Day Unplanned Readmissions After Elective Lumbar Spine Surgery: A National Trend Analysis of 144 123 Patients. Neurosurgery 2018, 84: 758-767. PMID: 29893899, DOI: 10.1093/neuros/nyy215.Peer-Reviewed Original ResearchConceptsElective lumbar spine surgeryChronic obstructive pulmonary disorderLumbar spine surgeryNational Readmission DatabaseUnplanned hospital readmissionPatient risk factorsUnplanned readmissionHospital readmissionSpine surgeryDeficiency anemiaInsurance statusRisk factorsElective spinal surgeryUnplanned readmission rateObstructive pulmonary disorderMultivariate regression analysisPaucity of dataInpatient complicationsNational healthcare expendituresReadmission ratesDural tearPulmonary disordersIndependent associationPatient outcomesSpinal surgeryMinimally Invasive Lateral Access Surgery and Reoperation Rates: A Multi-Institution Retrospective Review of 2060 Patients
Nayar G, Wang T, Sankey EW, Berry-Candelario J, Elsamadicy AA, Back A, Karikari I, Isaacs R. Minimally Invasive Lateral Access Surgery and Reoperation Rates: A Multi-Institution Retrospective Review of 2060 Patients. World Neurosurgery 2018, 116: e744-e749. PMID: 29787875, DOI: 10.1016/j.wneu.2018.05.082.Peer-Reviewed Original ResearchConceptsRate of reoperationLateral access surgeryLumbar spine surgeryMore comorbiditiesSurgical approachSpine surgeryDecompressive lumbar spine surgeryElective lumbar spinal surgeryMulti-institution retrospective reviewAccess surgeryLower body mass indexLumbar spinal surgeryBody mass indexOpen posterior approachHealth care systemOnly significant predictorAdditional readmissionsLT cohortOP cohortOP surgeryReoperation ratePatient demographicsSurgical complicationsRetrospective reviewMass indexDoes Nasal Carriage of Staphylococcus aureus Increase the Risk of Postoperative Infections After Elective Spine Surgery: Do Most Infections Occur in Carriers?
Adogwa O, Vuong VD, Elsamadicy AA, Lilly DT, Desai SA, Khalid S, Cheng J, Bagley CA. Does Nasal Carriage of Staphylococcus aureus Increase the Risk of Postoperative Infections After Elective Spine Surgery: Do Most Infections Occur in Carriers? World Neurosurgery 2018, 116: e519-e524. PMID: 29772370, DOI: 10.1016/j.wneu.2018.05.025.Peer-Reviewed Original ResearchConceptsSurgical site infectionElective spine surgeryWound infectionNasal colonizationSite infectionSpine surgeryCases of SSIPost-operative surgical site infectionDirect medical record reviewAdult spinal deformity surgeryProspective multi-institutional studyLocal vancomycin powderPostoperative wound infectionDeep wound infectionHistory of diabetesMajority of patientsMedical record reviewDay of surgeryBody mass indexStandard deviation agePost-operative infectionSpinal deformity surgeryMulti-institutional studyBaseline characteristicsNasal carriageInfluence of racial disparities on patient-reported satisfaction and short- and long-term perception of health status after elective lumbar spine surgery.
Elsamadicy AA, Kemeny H, Adogwa O, Sankey EW, Goodwin CR, Yarbrough CK, Lad SP, Karikari IO, Gottfried ON. Influence of racial disparities on patient-reported satisfaction and short- and long-term perception of health status after elective lumbar spine surgery. Journal Of Neurosurgery Spine 2018, 29: 40-45. PMID: 29701564, DOI: 10.3171/2017.12.spine171079.Peer-Reviewed Original ResearchMeSH KeywordsBlack or African AmericanDiagnostic Self EvaluationDisability EvaluationElective Surgical ProceduresFemaleHealth StatusHealthcare DisparitiesHumansLumbar VertebraeMaleMiddle AgedPainPatient Reported Outcome MeasuresPatient SatisfactionPrevalenceProspective StudiesRetrospective StudiesSelf ConceptTime FactorsWhite PeopleConceptsElective lumbar spine surgeryPatient-reported outcomesLumbar spine surgerySpine surgeryPatient satisfactionRacial disparitiesPatient demographicsReadmission ratesWhite patientsAA patientsMedical recordsLong-term patient-reported outcomesOverall patient-reported outcomeGreater body mass indexBaseline patient demographicsInferior surgical outcomesVAS-LP scoresPatient-reported satisfactionOverall patient satisfactionBody mass indexVisual analog scaleAfrican American patientsPatient-specific factorsPatient satisfaction measuresPerception of healthPreoperative Hemoglobin Level is Associated with Increased Health Care Use After Elective Spinal Fusion (≥3 Levels) in Elderly Male Patients with Spine Deformity
Elsamadicy AA, Adogwa O, Ongele M, Sergesketter AR, Tarnasky A, Lubkin DET, Drysdale N, Cheng J, Bagley CA, Karikari IO. Preoperative Hemoglobin Level is Associated with Increased Health Care Use After Elective Spinal Fusion (≥3 Levels) in Elderly Male Patients with Spine Deformity. World Neurosurgery 2018, 112: e348-e354. PMID: 29355811, DOI: 10.1016/j.wneu.2018.01.046.Peer-Reviewed Original ResearchConceptsElderly male patientsPreoperative Hgb levelsElective spinal fusionHealth care useHgb levelsSpinal fusionMale patientsPostoperative deliriumHemoglobin levelsCare useMean Hgb levelsNon-wound infectionsPreoperative hemoglobin levelLower hemoglobin levelsLower Hgb levelsQuality of careMajor academic institutionPreoperative HgbHospital stayPreoperative levelsPrimary outcomePreoperative identificationHematoma formationMedical recordsSpine surgeryInterdisciplinary Care Model Independently Decreases Use of Critical Care Services After Corrective Surgery for Adult Degenerative Scoliosis
Adogwa O, Elsamadicy AA, Sergesketter AR, Ongele M, Vuong V, Khalid S, Moreno J, Cheng J, Karikari IO, Bagley CA. Interdisciplinary Care Model Independently Decreases Use of Critical Care Services After Corrective Surgery for Adult Degenerative Scoliosis. World Neurosurgery 2018, 111: e845-e849. PMID: 29317368, DOI: 10.1016/j.wneu.2017.12.180.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCase ManagementClinical ProtocolsCohort StudiesCritical CareDecompression, SurgicalFemaleGeriatricsHumansLumbar VertebraeMaleNeurosurgical ProceduresPatient Care TeamPostoperative CarePostoperative ComplicationsRetrospective StudiesScoliosisSpinal FusionTreatment OutcomeConceptsElderly patientsCritical care servicesICU transferIndependent predictorsCorrective surgeryFusion surgeryComanagement modelSpine surgeryCare servicesComplex lumbar spine surgeryTeam approachIntensive care unit resourcesPeri-operative optimizationSenior Health (POSH) programDuration of surgeryLumbar spine surgeryInterdisciplinary care modelLong-term outcomesLumbar fusion surgeryMajor academic medical centerAdult degenerative scoliosisAcademic medical centerInterdisciplinary team approachPOSH cohortHospital course
2017
Geriatric comanagement reduces perioperative complications and shortens duration of hospital stay after lumbar spine surgery: a prospective single-institution experience.
Adogwa O, Elsamadicy AA, Vuong VD, Moreno J, Cheng J, Karikari IO, Bagley CA. Geriatric comanagement reduces perioperative complications and shortens duration of hospital stay after lumbar spine surgery: a prospective single-institution experience. Journal Of Neurosurgery Spine 2017, 27: 670-675. PMID: 28960161, DOI: 10.3171/2017.5.spine17199.Peer-Reviewed Original ResearchConceptsLumbar spine surgeryHospital stayPOSH cohortElderly patientsSpine surgeryGeriatric comanagementPerioperative complicationsComplex lumbar spine surgeryElective lumbar spine surgeryMedical comorbid conditionsSenior Health (POSH) programDays of dischargeElective spinal surgerySingle institution experienceMajority of patientsNursing home admissionLumbar fusion surgeryResults One hundred twentyMajor academic medical centerAdult degenerative scoliosisAcademic medical centerHospital complicationsSurgical screeningPostoperative complicationsBaseline characteristicsImpact of Gender Disparities on Short-Term and Long-Term Patient Reported Outcomes and Satisfaction Measures After Elective Lumbar Spine Surgery: A Single Institutional Study of 384 Patients
Elsamadicy AA, Reddy GB, Nayar G, Sergesketter A, Zakare-Fagbamila R, Karikari IO, Gottfried ON. Impact of Gender Disparities on Short-Term and Long-Term Patient Reported Outcomes and Satisfaction Measures After Elective Lumbar Spine Surgery: A Single Institutional Study of 384 Patients. World Neurosurgery 2017, 107: 952-958. PMID: 28743671, DOI: 10.1016/j.wneu.2017.07.082.Peer-Reviewed Original ResearchConceptsElective lumbar spine surgeryLumbar spine surgeryVisual analog scaleSpine surgeryMale cohortPerception of healthFemale cohortAnalog scaleMean changeBaseline patient-reported outcome measuresVisual analog scale leg painEuroQol 5 dimensions questionnairePatient-reported outcome measuresPatient-reported outcome instrumentsBaseline patient demographicsLonger hospital stayOswestry Disability IndexSingle institutional studyOverall patient satisfactionLong-term patientsPatient-reported outcomesPatient satisfaction measuresPaucity of dataSpine OutcomesDisability Index