Hungarian-born biochemist Dr. Katalin Karikó, renowned for her pioneering work on mRNA technology, recently engaged in an illuminating conversation with Carl Zimmer, a celebrated science writer and member of the Molecular Biophysics & Biochemistry (MB&B) department. Karikó’s revolutionary contributions to the development of mRNA vaccines, including those that played a pivotal role in combating COVID-19, earned her the 2023 Nobel Prize and cemented her legacy in modern immunology.
Dr. Karikó’s research has fundamentally changed how scientists understand the interaction between mRNA and the immune system. This breakthrough not only enabled the rapid development of lifesaving COVID-19 vaccines but also opened new horizons for mRNA-based therapies targeting a range of diseases. During the interview, Karikó reflected on the challenges of her early work, her persistence in pursuing mRNA technology despite skepticism, and the impact of her discoveries on global health.
Carl Zimmer, a columnist for The New York Times and an author of many acclaimed science books, including the forthcoming Air-Borne: The Hidden History of the Life We Breathe, brought his signature curiosity and expertise to the conversation. Zimmer, a faculty member in the MB&B department, guided the discussion to explore not only the science behind Karikó’s achievements but also the personal and professional journey that led to her groundbreaking success.
The event was presented by the Cold Spring Harbor Laboratory Center for Humanities and History of Modern Biology in collaboration with the BGI Nobel Laureate Archives Program. It highlighted the intersection of scientific innovation and human perseverance, offering attendees a rare glimpse into the life and work of a Nobel Laureate who has saved millions of lives worldwide.