Non-Treatment Studies
Modulation of Functional Connectivity and Fear Extinction Abnormalities
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HIC 2000039024
The purpose of this study is to test whether transcranial direct current stimulation (tDCS), a form of safe and mild electrical stimulation, affects processes in the brain related to the treatment of anxiety. Three MRI brain imaging scans will also be completed during this three-day study.
Brain imaging in tic disorders and OCD
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HIC: 2000021811
Evidence indicates that dopamine may be dysregulated in people with tic disorders and potentially in those with OCD as well. We are using positron emission tomography (PET), a form of non-invasive brain imaging, to examine dopamine receptor activity among people with and without both tics and OCD. We hope to better understand if and how dopamine dysregulation may be involved in tic disorders and OCD.
Individually Measured Phenotypes to Advance Computational Translation in Mental Health (IMPACT-MH)
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HIC: 2000036987
This study is investigating how mental health symptoms change and develop over time, among people with OCD as well as other mental health conditions. We will be collecting clinical information using various methods, including interviews, questionnaires, and computer tasks. These appointments will be both in-person and virtual over the course of about two years.
Exploring the genetics of OCD
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HIC 0803003626
It is clear that the risk for developing OCD depends in part on our genes; but the specific genes that contribute to OCD, and how they do so, are not well understood. Patients who we see in our clinic have the opportunity to give blood for genetic analysis. By comparing the specific genes of patients with OCD with other patients or with individuals with no psychiatric diagnosis, we hope to better understand the various complicated factors that contribute to the genetics of the illness.
Exercise and OCD
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HIC: 2000040629
Research suggests exercise can bring psychological benefits to people with OCD. It has also been shown to improve performance on tasks of cognitive flexibility, which is often impaired in OCD. This study is testing how a single session of low or moderate intensity exercise may affect both cognitive flexibility and symptom reactivity in people with OCD.
ClinicalTrials.gov ID: NCT07103902