2019
The Association of Impulsivity and Family History of Alcohol Use Disorder on Alcohol Use and Consequences
Haeny AM, Gueorguieva R, Morean ME, Krishnan‐Sarin S, DeMartini KS, Pearlson GD, Anticevic A, Krystal JH, O'Malley SS. The Association of Impulsivity and Family History of Alcohol Use Disorder on Alcohol Use and Consequences. Alcohol Clinical And Experimental Research 2019, 44: 159-167. PMID: 31693193, PMCID: PMC6981005, DOI: 10.1111/acer.14230.Peer-Reviewed Original ResearchConceptsFacets of impulsivityBarratt Impulsiveness ScaleAlcohol-related problemsAlcohol use disorderProblem drinkingAssociation of impulsivityImpulsivity-related traitsAlcohol-related consequencesUse disordersFHP individualsAlcohol outcomesImpulsiveness ScaleImpulsivityProblematic drinkingFHN individualsDrinking quantityAlcohol quantityTranslational neuroscienceAlcohol misuseAlcohol useTransdisciplinary Tobacco Use Research CenterMain effectAnalysis of covariancePhenotypic riskStrong positive association
2013
Effects of memantine on event-related potential, oscillations, and complexity in individuals with and without family histories of alcoholism.
Narayanan B, Stevens MC, Jiantonio RE, Krystal JH, Pearlson GD. Effects of memantine on event-related potential, oscillations, and complexity in individuals with and without family histories of alcoholism. Journal Of Studies On Alcohol And Drugs 2013, 74: 245-57. PMID: 23384372, PMCID: PMC3568163, DOI: 10.15288/jsad.2013.74.245.Peer-Reviewed Original ResearchConceptsNMDA receptor functionFHN subjectsFamily historyReceptor functionFHP individualsAlpha activityN-methyl-D-aspartate receptor functionNMDA receptor antagonist memantineEffects of memantineAuditory oddball discrimination taskPositive family historyFamily history-negative subjectsEvent-related potentialsAlcoholism family historyCortical information processingOddball discrimination taskFHN individualsMemantine administrationAcute effectsDrug interactionsP3b amplitudeFHP subjectsMemantineSeparate occasionsTheta activity