1991
Potentiation of the effects of reward-related stimuli by dopaminergic-dependent mechanisms in the nucleus accumbens
Cador M, Taylor J, Robbins T. Potentiation of the effects of reward-related stimuli by dopaminergic-dependent mechanisms in the nucleus accumbens. Psychopharmacology 1991, 104: 377-385. PMID: 1924645, DOI: 10.1007/bf02246039.Peer-Reviewed Original ResearchConceptsDorsal noradrenergic bundleDose-dependent increaseDA-dependent mechanismSignificant dose-dependent increaseSmaller infusion volumesDA infusionDA receptorsAlpha-flupenthixolNoradrenergic bundleSystemic doseProfound depletionNucleus accumbensReward-related processesInfusion volumeNeurotoxic lesionsNA levelsNeurochemical mediationNoradrenalinePotentiationCONDITIONED REINFORCEMENTDopamineReward-related stimuliConditioned reinforcersAmphetamineDoses
1989
Limbic-striatal interactions in reward-related processes
Robbins T, Cador M, Taylor J, Everitt B. Limbic-striatal interactions in reward-related processes. Neuroscience & Biobehavioral Reviews 1989, 13: 155-162. PMID: 2682402, DOI: 10.1016/s0149-7634(89)80025-9.Peer-Reviewed Original ResearchConceptsVentral striatumDA depletionIndirect dopamine agonist d-amphetamineStriatal DA depletionReward-related stimuliAgonist d-amphetamineSelective stimulatory effectDA-dependent processesBasolateral nucleusD-amphetamineExcitotoxic lesionsReward-related processesSecond-order scheduleDorsal striatumStriatumAmygdala lesionsStimulatory effectLesionsSimilar discriminative propertiesDiscriminative propertiesOrder schedulePredictive associationsSexual reinforcementDorsalParallel findings