1996
Eye Movements and Psychopathology in Schizophrenia and Bipolar Disorder
TIEN A, ROSS D, PEARLSON G, STRAUSS M. Eye Movements and Psychopathology in Schizophrenia and Bipolar Disorder. The Journal Of Nervous And Mental Disease 1996, 184: 331-338. PMID: 8642381, DOI: 10.1097/00005053-199606000-00001.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedAttentionBipolar DisorderEye MovementsFemaleHumansIntelligence TestsMaleMiddle AgedMultivariate AnalysisNeuropsychological TestsPsychiatric Status Rating ScalesPursuit, SmoothReaction TimeRegression AnalysisSaccadesSchizophreniaSchizophrenic PsychologySex FactorsVisual PerceptionSchizophrenia: A Disease of Heteromodal Association Cortex?
Pearlson G, Petty R, Ross C, Tien A. Schizophrenia: A Disease of Heteromodal Association Cortex? Neuropsychopharmacology 1996, 14: 1-17. PMID: 8719025, DOI: 10.1016/s0893-133x(96)80054-6.Peer-Reviewed Original ResearchMeSH KeywordsCerebral CortexHumansNeuropsychological TestsPrefrontal CortexSchizophreniaSchizophrenic PsychologyConceptsHeteromodal association cortexAssociation cortexLocal gray matter volumeMultiple brain areasGray matter volumeNeuro-imaging studiesNeuropathologic examinationClinical featuresCortical abnormalitiesPrimary involvementBrain areasMatter volumeCortexDiseaseSchizophreniaConsiderable evidenceMagnetic resonanceFindings formNetwork of circuitsLesionsNeocortexAbnormalities
1995
Cingulate gyrus in schizophrenic patients and normal volunteers
Noga J, Aylward E, Barta P, Pearlson G. Cingulate gyrus in schizophrenic patients and normal volunteers. Psychiatry Research 1995, 61: 201-208. PMID: 8748465, DOI: 10.1016/0925-4927(95)02612-2.Peer-Reviewed Original ResearchConceptsSeverity of hallucinationsCingulate gyrusNormal volunteersMagnetic resonance imaging sectionsPosterior cingulate gyrusPatient groupSchizophrenic patientsBrain volumeParental socioeconomic statusCingulate regionsPatientsCingulate structuresSocioeconomic statusInverse correlationGyrusInterrater reliabilityBonferroni correctionSchizophreniaSeverityVolunteersHallucinationsImaging sectionsLateral asymmetryGroupPosterior superior temporal gyrus in schizophrenia: grey matter changes and clinical correlates
Menon R, Barta P, Aylward E, Richards S, Vaughn D, Tien A, Harris G, Pearlson G. Posterior superior temporal gyrus in schizophrenia: grey matter changes and clinical correlates. Schizophrenia Research 1995, 16: 127-135. PMID: 7577766, DOI: 10.1016/0920-9964(94)00067-i.Peer-Reviewed Original Research
1993
Dopamine D2 receptor density estimates in schizophrenia: A positron emission tomography study with11C-N-methylspiperone
Tune L, Wong D, Pearlson G, Strauss M, Young T, Shaya E, Dannals R, Wilson A, Ravert H, Sapp J, Cooper T, Chase G, Wagner H. Dopamine D2 receptor density estimates in schizophrenia: A positron emission tomography study with11C-N-methylspiperone. Psychiatry Research 1993, 49: 219-237. PMID: 7909948, DOI: 10.1016/0165-1781(93)90063-m.Peer-Reviewed Original ResearchConceptsPositron emission tomographySchizophrenic patientsBmax valuesEntire groupControl subjectsEmission tomographyDopamine D2 receptor densityNeuroleptic-free patientsDuration of illnessChronic schizophrenic patientsD2 receptor densityClinical characteristicsPatient populationReceptor abnormalitiesCorpus striatumClinical dataReceptor densityPatientsControl groupFunction of ageLate manifestationDifferent radioligandsFour-compartment modelSignificant differencesRadioligand
1988
Late-Onset Schizophrenia Studying Clinical Validity
V.Jeste D, Harris M, Pearlson G, Rabins P, Lesser I, Miller B, Coles C, Yassa R. Late-Onset Schizophrenia Studying Clinical Validity. Psychiatric Clinics Of North America 1988, 11: 1-13. PMID: 3380754, DOI: 10.1016/s0193-953x(18)30513-6.Peer-Reviewed Original ResearchConceptsLate-onset schizophreniaSchizophrenic patientsYoung schizophrenic patientsClinical characteristicsChronic courseAge 45Onset schizophreniaParanoid typeClinical validityAuditory hallucinationsLow dosesBizarre delusionsSchizophreniaPatientsRelevant literatureNeurolepticsIllnessDosesHallucinations
1985
Symptomatic, Familial, Perinatal, and Social Correlates of Computerized Axial Tomography (CAT) Changes in Schizophrenics and Bipolars
PEARLSON G, GARBACZ D, MOBERG P, AHN H, DEPAULO J. Symptomatic, Familial, Perinatal, and Social Correlates of Computerized Axial Tomography (CAT) Changes in Schizophrenics and Bipolars. The Journal Of Nervous And Mental Disease 1985, 173: 42-50. PMID: 3965611, DOI: 10.1097/00005053-198501000-00007.Peer-Reviewed Original ResearchConceptsVentricular enlargementFamily historyNegative symptomsComputerized axial tomography scanLateral ventricular enlargementAxial tomography scanPast psychiatric historyEarly brain damageMarked ventricular enlargementSubgroup of schizophrenicsPoor premorbid adjustmentLateral ventricularTomography changesBrain ratioPatient groupBrain damageTomography scanPsychiatric illnessPsychiatric historyBipolar patientsNormal controlsEarly onsetPatientsPremorbid adjustmentSignificant proportion
1984
Lateral ventricular enlargement associated with persistent unemployment and negative symptoms in both schizophrenia and bipolar disorder
Pearlson G, Garbacz D, Breakey W, Ahn H, DePaulo J. Lateral ventricular enlargement associated with persistent unemployment and negative symptoms in both schizophrenia and bipolar disorder. Psychiatry Research 1984, 12: 1-9. PMID: 6589656, DOI: 10.1016/0165-1781(84)90133-1.Peer-Reviewed Original Research