1995
In Vivo D2 Dopamine Receptor Density in Psychotic and Nonpsychotic Patients With Bipolar Disorder
Pearlson G, Wong D, Tune L, Ross C, Chase G, Links J, Dannals R, Wilson A, Ravert H, Wagner H, DePaulo J. In Vivo D2 Dopamine Receptor Density in Psychotic and Nonpsychotic Patients With Bipolar Disorder. JAMA Psychiatry 1995, 52: 471-477. PMID: 7771917, DOI: 10.1001/archpsyc.1995.03950180057008.Peer-Reviewed Original ResearchConceptsSchizophrenic patientsBipolar disorderBmax valuesNonpsychotic patientsNormal controlsPsychotic symptomsPsychotic patientsAffective disordersPositron emission tomographic scansD2 dopamine receptor densityNeuroleptic-naive schizophrenic patientsPositron emission tomographic studiesDopamine receptor densityReceptor density valuesDSM-III criteriaPresent State ExaminationPresence of psychosisEmission tomographic studiesHigher Bmax valuesPsychotic bipolar disorderNeuroleptic medicationReceptor BmaxMood abnormalitiesReceptor valuesTomographic scan
1988
Positron emission tomography imaging of dopamine and serotonin receptors in Huntington's chorea.
Wong D, Wagner H, Links J, Dannals R, Folstein S, Ravert H, Tune L, Pearlson G, Frost J, Folstein M. Positron emission tomography imaging of dopamine and serotonin receptors in Huntington's chorea. American Journal Of Physiologic Imaging 1988, 3: 51. PMID: 2968808.Peer-Reviewed Original Research
1986
Positron Emission Tomography Reveals Elevated D2 Dopamine Receptors in Drug-Naive Schizophrenics
Wong D, Wagner H, Tune L, Dannals R, Pearlson G, Links J, Tamminga C, Broussolle E, Ravert H, Wilson A, Toung J, Malat J, Williams J, O'Tuama L, Snyder S, Kuhar M, Gjedde A. Positron Emission Tomography Reveals Elevated D2 Dopamine Receptors in Drug-Naive Schizophrenics. Science 1986, 234: 1558-1563. PMID: 2878495, DOI: 10.1126/science.2878495.Peer-Reviewed Original ResearchConceptsD2 dopamine receptorsD2 dopamine receptor densityPositron emission tomographyGroup of patientsDopamine receptor densityDopamine receptorsCaudate nucleusReceptor densityNormal volunteersEmission tomographyDrug-naive schizophrenicsNumber of receptorsMost patientsBasal gangliaNeuroleptic drugsPostmortem studiesBiochemical abnormalitiesPatientsPsychiatric diseasesSchizophreniaReceptorsDrugsVolunteersTomographyGroup
1985
Dopamine receptor binding of C-11-3-N-methylspiperone in the caudate in schizophrenia and bipolar disorder: a preliminary report.
Wong D, Wagner H, Pearlson G, Dannals R, Links J, Ravert H, Wilson A, Suneja S, Bjorvvinssen E, Kuhar M. Dopamine receptor binding of C-11-3-N-methylspiperone in the caudate in schizophrenia and bipolar disorder: a preliminary report. Psychopharmacology Bulletin 1985, 21: 595-8. PMID: 4034877.Peer-Reviewed Original ResearchMeSH KeywordsAdultBipolar DisorderButyrophenonesCaudate NucleusHumansReceptors, DopamineSchizophreniaSpiperoneConceptsDopamine receptor binding