2012
D-Cycloserine for Treatment Nonresponders With Obsessive-Compulsive Disorder: A Case Report
Norberg M, Gilliam C, Villavicencio A, Pearlson G, Tolin D. D-Cycloserine for Treatment Nonresponders With Obsessive-Compulsive Disorder: A Case Report. Cognitive And Behavioral Practice 2012, 19: 338-345. DOI: 10.1016/j.cbpra.2011.05.002.Peer-Reviewed Original ResearchObsessive-compulsive disorderN-methyl-D-aspartate (NMDA) receptor partial agonist D-cycloserinePartial agonist D-cycloserineThird of patientsD-cycloserineCourse of ERPReuptake inhibitorsCase reportTreatment nonrespondersEffective treatmentPatientsPrior treatmentResponse preventionGreater reductionTreatmentDisordersPresent studyAdequate responseNonrespondersPrevention
1994
Mapping of SPECT regional cerebral perfusion abnormalities in obsessive‐compulsive disorder
Harris G, Hoehn‐Saric R, Lewis R, Pearlson G, Streeter C. Mapping of SPECT regional cerebral perfusion abnormalities in obsessive‐compulsive disorder. Human Brain Mapping 1994, 1: 237-248. PMID: 24591194, DOI: 10.1002/hbm.460010403.Peer-Reviewed Original ResearchCerebral perfusion abnormalitiesObsessive-compulsive disorderMagnetic resonance imagingPerfusion abnormalitiesObsessive-compulsive patientsPrior functional neuroimaging studiesSex-matched control subjectsCerebral perfusion differencesRelative cerebral perfusionRight visual association cortexRight frontal cortexVisual association cortexFunctional imaging studiesSingle photon emissionFunctional neuroimaging studiesCerebral valuesCerebral perfusionFrontal perfusionControl subjectsStudies of OCDFrontal cortexCaudate nucleusPerfusion differencesAssociation cortexRegional abnormalities
1993
Single Photon Emission Computed Tomography in Obsessive-Compulsive Disorder
Harris G, Pearlson G, Hoehn-Saric R. Single Photon Emission Computed Tomography in Obsessive-Compulsive Disorder. JAMA Psychiatry 1993, 50: 498-499. PMID: 8498888, DOI: 10.1001/archpsyc.1993.01820180100015.Peer-Reviewed Original ResearchConceptsOrbital frontal regionsObsessive-compulsive disorderSingle photon emissionBlood flowRegional cerebral blood flowCortical blood flowGroup of patientsCerebral blood flowMedial frontal regionsSPECT studiesAnatomical locationPatientsCompulsive disorderPhoton emissionEt al1DisordersTomographyGroup