2000
White matter hyperintensity volume in late‐onset and early‐onset schizophrenia
Rivkin P, Kraut M, Barta P, Anthony J, Arria A, Pearlson G. White matter hyperintensity volume in late‐onset and early‐onset schizophrenia. International Journal Of Geriatric Psychiatry 2000, 15: 1085-1089. PMID: 11180463, DOI: 10.1002/1099-1166(200012)15:12<1085::aid-gps250>3.0.co;2-x.Peer-Reviewed Original ResearchConceptsWhite matter hyperintensitiesMagnetic resonance imagingWhite matter hyperintensity volumeLate-onset psychosisEarly-onset schizophreniaEarly-onset schizophrenicsNeuro-imaging studiesNeuro-degenerative processesControl subjectsCase ascertainmentOnset psychosisHyperintensity volumeMatter hyperintensitiesOnset schizophreniaWMH volumeAnatomic correlatesResonance imagingStudy designSchizophreniaSignificant differencesWMH measurementsPresent studySchizophrenicsContinuous measureLatent vulnerability
1996
Schizophrenia: A Disease of Heteromodal Association Cortex?
Pearlson G, Petty R, Ross C, Tien A. Schizophrenia: A Disease of Heteromodal Association Cortex? Neuropsychopharmacology 1996, 14: 1-17. PMID: 8719025, DOI: 10.1016/s0893-133x(96)80054-6.Peer-Reviewed Original ResearchConceptsHeteromodal association cortexAssociation cortexLocal gray matter volumeMultiple brain areasGray matter volumeNeuro-imaging studiesNeuropathologic examinationClinical featuresCortical abnormalitiesPrimary involvementBrain areasMatter volumeCortexDiseaseSchizophreniaConsiderable evidenceMagnetic resonanceFindings formNetwork of circuitsLesionsNeocortexAbnormalities