Marcella Nunez-Smith, MD, MHS
Associate Dean for Health Equity Research and C.N.H. Long Professor of Internal Medicine (General Medicine), of Epidemiology (Chronic Disease) and of Public Health (Social And Behavioral Sciences) & Professor of Internal Medicine (General Medicine)Cards
Additional Titles
Affiliated Faculty, Yale Institute for Global Health
Founding Director, Equity Research and Innovation Center (ERIC), Yale School of Medicine
Director, Center for Research Engagement (CRE)
Director, Center for Community Engagement and Health Equity
Deputy Director for Health Equity Research and Workforce Development, Yale Center for Clinical Investigation (YCCI)
Director, Pozen-Commonwealth Fund Fellowship in Health Equity Leadership
Publications Overview
- 113 Publications
- 4,278 Citations
- 86 Yale Co-Authors
Appointments
Additional Titles
Affiliated Faculty, Yale Institute for Global Health
Founding Director, Equity Research and Innovation Center (ERIC), Yale School of Medicine
Director, Center for Research Engagement (CRE)
Director, Center for Community Engagement and Health Equity
Deputy Director for Health Equity Research and Workforce Development, Yale Center for Clinical Investigation (YCCI)
Director, Pozen-Commonwealth Fund Fellowship in Health Equity Leadership
Publications Overview
- 113 Publications
- 4,278 Citations
- 86 Yale Co-Authors
Appointments
Additional Titles
Affiliated Faculty, Yale Institute for Global Health
Founding Director, Equity Research and Innovation Center (ERIC), Yale School of Medicine
Director, Center for Research Engagement (CRE)
Director, Center for Community Engagement and Health Equity
Deputy Director for Health Equity Research and Workforce Development, Yale Center for Clinical Investigation (YCCI)
Director, Pozen-Commonwealth Fund Fellowship in Health Equity Leadership
Publications Overview
- 113 Publications
- 4,278 Citations
- 86 Yale Co-Authors
About
Titles
Associate Dean for Health Equity Research and C.N.H. Long Professor of Internal Medicine (General Medicine), of Epidemiology (Chronic Disease) and of Public Health (Social And Behavioral Sciences) & Professor of Internal Medicine (General Medicine)
Affiliated Faculty, Yale Institute for Global Health; Founding Director, Equity Research and Innovation Center (ERIC), Yale School of Medicine; Director, Center for Research Engagement (CRE); Director, Center for Community Engagement and Health Equity; Deputy Director for Health Equity Research and Workforce Development, Yale Center for Clinical Investigation (YCCI); Director, Pozen-Commonwealth Fund Fellowship in Health Equity Leadership
Biography
Dr. Nunez-Smith is Inaugural Associate Dean for Health Equity Research; C.N.H Long Professor of Internal Medicine, Public Health, and Management; Founding Director of the Equity Research and Innovation Center (ERIC); Director of the Center for Research Engagement (CRE); Associate Cancer Center Director for Community Outreach and Engagement at Yale Cancer Center; Chief Health Equity Officer at Smilow Cancer Hospital; Deputy Director for Health Equity Research and Workforce Development at the Yale Center for Clinical Investigation; Core Faculty in the National Clinician Scholars Program; Research Faculty in the Global Health Leadership Initiative; Director of the Pozen-Commonwealth Fund Fellowship in Health Equity Leadership; and Co-Director of the Doris Duke Clinical Research Fellowship.
Dr. Nunez-Smith’s research focuses on promoting health and healthcare equity for structurally marginalized populations with an emphasis on centering community engagement, supporting healthcare workforce diversity and development, developing patient reported measurements of healthcare quality, and identifying regional strategies to reduce the global burden of non-communicable diseases. Dr. Nunez-Smith has extensive expertise in examining the effects of social and structural determinants of health, systemic influences contributing to health disparities, health equity improvement, and community-academic partnered scholarship. In addition to primary data collection, management, and analysis, ERIC has institutional expertise in qualitative and mixed methods, population health, and medical informatics.
Dr. Nunez-Smith is the principal investigator on many NIH and foundation-funded research projects, including an NIH-funded project to develop a tool to assess patient reported experiences of discrimination in healthcare. She has conducted an investigation of the promotion and retention of diversity in academic medical school faculty and has published numerous articles on the experiences of minority students and faculty. Funded by NIH/NIMHD, she established the Eastern Caribbean Health Outcomes Research Network (ECHORN), a research collaborative across four Eastern Caribbean islands, supporting several chronic disease research projects and enhancing health outcomes research and leadership capacity in the region; the flagship ECHORN Cohort Study recruited and is following a community-dwelling adult cohort (n=3000) to examine novel chronic disease risk and protective factors. She received NIH/NHLBI funding to build upon this work by recruiting children into an expanded intergenerational ECHORN cohort, inclusive of a biorepository. She is also PI on one of five NIH/NIMHD-funded Transdisciplinary Collaborative Centers on Health Disparities focused on Precision Medicine which leverages the ECHORN infrastructure to conduct collaborative research on hypertension and diabetes.
Most recently, as the COVID-19 pandemic has shed national attention on the health and healthcare disparities of marginalized populations, she received NIH funding to leverage ECHORN to improve the COVID-19 testing cascade in Puerto Rico and the US Virgin Islands. Further, she was called upon to chair the Governor’s ReOpen CT Advisory Group Community Committee and was subsequently named co-chair of the Biden-Harris Transition COVID-19 Advisory Board. She served as Senior Advisor to the White House COVID-19 Response and Chair of the Presidential COVID-19 Health Equity Task Force at the Department of Health and Human Services.
Dr. Nunez-Smith has mentored dozens of trainees since completing fellowship and has received numerous awards for teaching and mentoring. An elected member of the National Academy of Medicine, Dr. Nunez-Smith is board certified in internal medicine, having completed residency training at Harvard University’s Brigham and Women’s Hospital and fellowship at the Yale Robert Wood Johnson Foundation Clinical Scholars Program, where she also received a Masters in Health Sciences.
Originally from the US Virgin Islands, she attended Jefferson Medical College, where she was inducted into the Alpha Omega Alpha Medical Honor Society, and she earned a BA in Biological Anthropology and Psychology at Swarthmore College.
Appointments
Office of the Dean, School of Medicine
Associate DeanDualGeneral Internal Medicine
ProfessorPrimaryChronic Disease Epidemiology
ProfessorSecondarySocial and Behavioral Sciences
ProfessorSecondary
Other Departments & Organizations
- Cancer Prevention and Control
- Center for Community Engagement and Health Equity (CEHE)
- Chronic Disease Epidemiology
- Climate Change and Health
- Dean's Advisory Council for LGBTQI Affairs
- Diabetes Research Center
- Directories
- Equity Research and Innovation Center (ERIC)
- General Internal Medicine
- Global Health Studies
- Internal Medicine
- MORE
- Obesity Research Working Group
- Office of Health Equity Research
- Office of the Dean, School of Medicine
- Social and Behavioral Sciences
- Yale Cancer Center
- Yale Center for Clinical Investigation (YCCI)
- Yale Center for Implementation Science (YCIS)
- Yale Institute for Global Health
- Yale Medicine
- Yale Medicine Outlist
- Yale School of Public Health
- Yale TCC
- Yale Ventures
- Yale-New Haven Hospital Primary Care Center
- YCC Diversity, Equity, and Inclusion
Education & Training
- MHS
- Yale University
- Post-doctoral Fellow
- Yale University School of Medicine
- Resident
- Brigham & Women's Hospital
- Chief Resident
- Veteran Affairs Medical Center, West Roxbury
- Intern
- Brigham & Women’s Hospital
- MD
- Jefferson Medical College
- BA
- Swarthmore College
Research
Overview
Medical Research Interests
Public Health Interests
ORCID
0000-0003-2797-4756- View Lab Website
Equity Research and Innovation Center
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Josefa L. Martinez, PhD, MHS
Leslie Curry, PhD, MPH
Carol Oladele, PhD, MPH
Harlan Krumholz, MD, SM
Mayur M. Desai, PhD, MPH, FACE
Karen Wang, MD, MHS
Healthcare Disparities
Caribbean Region
COVID-19
Socioeconomic Factors
Social Determinants of Health
Chronic Disease
Publications
2025
Mediators of Racial Inequities in Non‐Small Cell Lung Cancer Care
Hamid S, Lee D, Herrin J, Yu J, Pollack C, Dean L, Gaddy J, Oladele C, Feder S, Canavan M, Nunez-Smith M, Soulos P, Gross C. Mediators of Racial Inequities in Non‐Small Cell Lung Cancer Care. Cancer Medicine 2025, 14: e70757. PMID: 40052387, DOI: 10.1002/cam4.70757.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsNon-small cell lung cancer carePhase of careSocioeconomic statusNon-small cell lung cancerIndividual-level socioeconomic statusNeighborhood-level socioeconomic statusMedicare-Medicaid dual eligibilityWhite patientsHealth care accessLung cancer careNon-Hispanic blacksIndirect effects of mediatorsDiagnosis stageStage-appropriate treatmentTwo-year survivalCancer careCare accessEffects of raceOptimal careDual eligiblesCareStructural racismRacial inequalityBlack patientsInadequate evaluationSociodemographic correlates of hypertension prevalence, awareness, and control in the Eastern Caribbean
Oladele C, Miller M, Adams O, Maharaj R, Nazario C, Nunez M, Nunez-Smith M, Desai M. Sociodemographic correlates of hypertension prevalence, awareness, and control in the Eastern Caribbean. The Lancet Regional Health - Americas 2025, 43: 101012. PMID: 40093852, PMCID: PMC11910123, DOI: 10.1016/j.lana.2025.101012.Peer-Reviewed Original ResearchConceptsPrevalence of hypertensionMinority healthSociodemographic correlatesHypertension prevalenceSelf-administered health surveyHypertension care cascadeLow physical activityCommunity-dwelling personsEducational attainmentSelf-reported hypertensionJoint National Committee on PreventionSource of healthcareHigher prevalence of hypertensionAssociated with awarenessLower educational attainmentPredictors of hypertensionAge of participantsControl of hypertensionTreatment of High Blood PressureNational InstitutePhysical activityHealth disparitiesHigh blood pressureCare cascadeHealth SurveyAssessing cardiovascular disease risk and social determinants of health: A comparative analysis of five risk estimation instruments using data from the Eastern Caribbean Health Outcomes Research Network
Schwartz J, Howitt C, Raman S, Nair S, Hassan S, Oladele C, Hambleton I, Sarpong D, Adams O, Maharaj R, Nazario C, Nunez M, Nunez-Smith M. Assessing cardiovascular disease risk and social determinants of health: A comparative analysis of five risk estimation instruments using data from the Eastern Caribbean Health Outcomes Research Network. PLOS ONE 2025, 20: e0316577. PMID: 39854547, PMCID: PMC11760610, DOI: 10.1371/journal.pone.0316577.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsCardiovascular disease riskSocial determinants of healthDeterminants of healthSocial determinantsRisk estimation toolsCardiovascular diseaseEstimate 10-year CVD riskCVD riskEastern Caribbean Health Outcomes Research NetworkCardiovascular disease risk estimatesHigh riskHigher level of educationHistory of cardiovascular diseaseHigher CVD riskMultivariate logistic regression modelEthnically diverse populationsResource-constrained settingsLogistic regression modelsNon-professional occupationsSDoH variablesLevel of educationSDoHPerceived social statusRisk toolFraminghamMedical School Curriculum Evaluation to Improve Health Equity Education
Nguemeni Tiako M, Sundaresh R, Nunez-Smith M, Shenson D, Sheares B. Medical School Curriculum Evaluation to Improve Health Equity Education. Journal Of General Internal Medicine 2025, 1-5. PMID: 39843676, DOI: 10.1007/s11606-024-09347-9.Peer-Reviewed Original ResearchConceptsHealth equity curriculumEquity educationStudent focus groupsHealth equityEducation policyUndergraduate medical educationClassroom teachingCurriculum evaluationResponsive to community needsCurriculumSocial justiceCourse directorsPhysician-patient relationshipEducationAxes of oppressionYale School of MedicineNational reviewFocus groupsStudentsMedical educationSchool of MedicineBlack Lives MatterMedical studentsStructural competencyCommunity needsEvaluation and adaptation of a two-way text messaging intervention in the WIC breastfeeding peer counseling program: A qualitative analysis
Martinez-Brockman J, Granner J, Buchanan B, Acosta L, Lonczak M, Goeschel L, Xu X, Curry L, Nunez-Smith M, Pérez-Escamilla R. Evaluation and adaptation of a two-way text messaging intervention in the WIC breastfeeding peer counseling program: A qualitative analysis. PLOS ONE 2025, 20: e0313779. PMID: 39787090, PMCID: PMC11717301, DOI: 10.1371/journal.pone.0313779.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsProgram impact pathwayCritical Quality Control PointsLow-income womenPeer counseling programPeer counselorsSpecial Supplemental Nutrition ProgramSupplemental Nutrition ProgramContinuity of careCounseling programQuality control pointsLactation AdviceDischarge supportIn-depth interviewsWIC mothersWIC programNutrition ProgramFeasibility trialWICCounseling supportLactation consultantsPeer counselingInfant healthQualitative studyCausal pathwaysBuy-in
2024
Caribbean data-sharing initiatives: activities of the Eastern Caribbean Health Outcomes Research Network
Wang K, Britton M, Hambleton I, Howitt C, Jeyaseelan S, Fraser K, Martinez-Brockman J, Whiteman S, Rajeevan H, Nunez-Smith M. Caribbean data-sharing initiatives: activities of the Eastern Caribbean Health Outcomes Research Network. BULL PAN AM HEALTH ORGAN 2024, 48: 1. PMID: 39687248, PMCID: PMC11648151, DOI: 10.26633/rpsp.2024.121.Peer-Reviewed Original ResearchConceptsEastern Caribbean Health Outcomes Research NetworkLongitudinal data resourcesCommunity-engaged processCommunity-engaged approachCommunity-dwelling adultsGovernment focusPower dynamicsResearch NetworkData-sharing infrastructureGreater accessParticipating communitiesCare principlesNoncommunicable diseasesUnited StatesDemocratize data accessCohort studyImpact of researchProtective factorsData dashboardsSecondary useIdentifying opportunitiesDissemination of dataDissemination of informationDemocracyFunding agenciesSupporting diversity in clinical trials: the equitable breakthroughs in medicine site maturity model
Harris T, Nunez-Smith M, Suttiratana S, Fretz S, Leonard S, Linnander E, Curry L. Supporting diversity in clinical trials: the equitable breakthroughs in medicine site maturity model. Trials 2024, 25: 764. PMID: 39543751, PMCID: PMC11566401, DOI: 10.1186/s13063-024-08594-9.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsSocial determinants of healthQuantitative self-report dataDeterminants of healthCommunity engagementHealth care providersRepresentation of diverse populationsSelf-reported dataSocial determinantsCare providersContent validityPotential participantsClinical trial capabilitiesClinical trial diversityDiverse populationsInclusion of diverse participantsClinical trialsAssessment of capabilitiesTrial infrastructureDiverse participantsU.S. sitesClinical researchAbstract BackgroundParticipantsDiversity effortsStructural assessmentDisentangling gender, sex, and biology: a mixed methods study of gender identity data collection tools
Alpert A, Hernandez T, Ruddick R, Manzano C, Adams S, Rivers L, Ramos-Pibernus A, Sevelius J, Poteat T, Obedin-Maliver J, Cicero E, Radix A, Lett E, Operario D, Chapman B, Wittink M, Cupertino A, Murchison G, Nunez-Smith M, Cartujano-Barrera F. Disentangling gender, sex, and biology: a mixed methods study of gender identity data collection tools. Patient Education And Counseling 2024, 130: 108473. PMID: 39471780, DOI: 10.1016/j.pec.2024.108473.Peer-Reviewed Original ResearchConceptsTGD peopleGender identity questionTGD participantsConflation of sexConcepts of sexIdentical questionsTGD adultsGender identityCommunity membersTGDContextual factorsQualitative dataGenderDecrease stigmaPeopleData collection toolTemplate analysisQuantitative dataAnalyzed quantitative dataCisgenderismCollective preferencesQuestionsTransgenderMedical careMixing methodDiagnostic experiences of Black and White patients with uterine cancer: A qualitative study
Britton M, Izampuye E, Clark M, Ornstein R, Nunez-Smith M, Wright J, Xu X. Diagnostic experiences of Black and White patients with uterine cancer: A qualitative study. Gynecologic Oncology 2024, 191: 67-73. PMID: 39362045, PMCID: PMC11637892, DOI: 10.1016/j.ygyno.2024.09.010.Peer-Reviewed Original ResearchConceptsDiagnosis of uterine cancerUterine cancerRacial disparitiesHealthcare systemSocial determinants of healthNon-Hispanic White (WhiteGynecologic careDeterminants of healthDiscriminatory experiencesSemi-structured interviewsPatient engagementSocial determinantsAcceptance of discomfortHealthcare accessPerceived barriersPatient experienceThematic analysisDiagnostic journeyQualitative studyAudio-recordedBlack respondentsWhite patientsNegative experiencesHealthcareStage II-IV diseaseUnderstanding Barriers and Facilitators to Disaster Preparedness in Federally Qualified Health Centers in the United States: A Mixed Methods Study
Hassan S, Wiciak M, Escobar K, del Mar González Montalvo M, Richards T, Villanueva H, Ortiz J, Evans D, Nunez-Smith M. Understanding Barriers and Facilitators to Disaster Preparedness in Federally Qualified Health Centers in the United States: A Mixed Methods Study. Disaster Medicine And Public Health Preparedness 2024, 18: e138. PMID: 39291834, DOI: 10.1017/dmp.2024.102.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsFederally Qualified Health CentersNon-communicable diseasesMultiple non-communicable diseasesMixed-methods study designDisaster preparednessQualified Health CentersQualitative dataMixed methods studyMental health disordersQualitative in-depth interviewsKnowledge of disaster preparednessExperiences of staffHealth disparitiesIn-depth interviewsUnderstanding barriersHealth centersMethods studyHealth disordersStudy designPuerto RicoQuantitative surveyCareNarrative approachPreparednessPerceived gap
Clinical Trials
Current Trials
Sight-saving Engagement and Evaluation in New Haven (SEEN) Program
HIC ID2000031731RoleSub InvestigatorPrimary Completion Date12/31/2022Recruiting Participants
Academic Achievements & Community Involvement
honor Elected Member to the National Academy of Medicine
National AwardNational Academy of MedicineDetails10/18/2021United States
Clinical Care
Overview
Clinical Specialties
Yale Medicine News
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News
- January 20, 2025Source: Yale Daily News
Unmasking alcohol: Yale experts debate alcohol’s cancer risk and labeling implications
- November 21, 2024
Research Assessment Model Strives to Enhance Diversity in Clinical Trials
- October 22, 2024
Health Equity Summit Celebrates Achievements, Plans Future Solutions
- October 01, 2024
Connecticut Health Foundation launches advisory committee for statewide blueprint on maternal health equity