2014
Evolutionary Systems Biology: Shifting Focus to the Context‐Dependency of Genetic Effects
Pavličev M, Wagner G. Evolutionary Systems Biology: Shifting Focus to the Context‐Dependency of Genetic Effects. 2014, 91-108. DOI: 10.1002/9781118398814.ch6.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
1998
Genetic measurement theory of epistatic effects
Wagner G, Laubichler M, Bagheri-Chaichian H. Genetic measurement theory of epistatic effects. Genetica 1998, 102-103: 569-580. PMID: 9766965, DOI: 10.1023/a:1017088321094.Peer-Reviewed Original ResearchConceptsEpistatic effectsGenotype-phenotype mapMendelian genetic systemMathematical population geneticsAverage additive effectPairs of lociGenetic architecturePopulation geneticsEvolutionary changeEvolutionary phenomenaGenetic systemGenotypic varianceMetabolic fluxSecond locusEpistasisGene substitutionMutation effectsAdditive effectAdult body weightGene effectsSecond mutationLocus BLociMutationsNegative interactionsGenetic measurement theory of epistatic effects
Wagner G, Laubichler M, Bagheri-Chaichian H. Genetic measurement theory of epistatic effects. Contemporary Issues In Genetics And Evolution 1998, 7: 569-580. DOI: 10.1007/978-94-011-5210-5_43.Peer-Reviewed Original ResearchEpistatic effectsGenotype-phenotype mapMendelian genetic systemMathematical population geneticsAverage additive effectPairs of lociGenetic architecturePopulation geneticsEvolutionary changeEvolutionary phenomenaGenetic systemGenotypic varianceMetabolic fluxSecond locusEpistasisGene substitutionMutation effectsAdditive effectAdult body weightGene effectsSecond mutationLocus BLociMutationsNegative interactions