2013
Cerebral gray matter volumes and low-frequency fluctuation of BOLD signals in cocaine dependence: Duration of use and gender difference
Ide JS, Zhang S, Hu S, Sinha R, Mazure CM, Li CS. Cerebral gray matter volumes and low-frequency fluctuation of BOLD signals in cocaine dependence: Duration of use and gender difference. Drug And Alcohol Dependence 2013, 134: 51-62. PMID: 24090712, PMCID: PMC3865077, DOI: 10.1016/j.drugalcdep.2013.09.004.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultCerebral CortexCocaine-Related DisordersEcho-Planar ImagingFemaleHumansMaleMiddle AgedSex CharacteristicsTime FactorsYoung AdultConceptsGray matter volumeSuperior frontal gyrusDuration of useGM volumeMatter volumeLow-frequency fluctuationsBOLD signalCingulate cortexCD individualsCocaine useCerebral gray matter volumeAlcohol useMiddle/posterior cingulate cortexRight superior frontal gyrusGM volume lossBilateral superior frontal gyrusHealthy control subjectsRight ventral putamenMagnetic resonance imagingChronic cocaine usePosterior cingulate cortexInfluence of ageEffect of ageControl subjectsVentral putamenError processing and gender-shared and -specific neural predictors of relapse in cocaine dependence
Luo X, Zhang S, Hu S, Bednarski SR, Erdman E, Farr OM, Hong KI, Sinha R, Mazure CM, Li CS. Error processing and gender-shared and -specific neural predictors of relapse in cocaine dependence. Brain 2013, 136: 1231-1244. PMID: 23485852, PMCID: PMC3613717, DOI: 10.1093/brain/awt040.Peer-Reviewed Original ResearchConceptsDorsal anterior cingulate cortexFunctional magnetic resonance imagingCognitive controlError-related activationError processingCocaine-dependent individualsAnterior cingulate cortexSignal taskCingulate cortexCocaine dependenceFunctional magnetic resonance imaging (fMRI) dataStop-signal taskTreatment-seeking individualsCross-sectional findingsModerate-sized cohortsBrain activationBehavioral treatmentNeural predictorsDrug useMagnetic resonance imaging dataStatistical Parametric Mapping 8Regional activationPsychosocial factorsSuccess trialsMagnetic resonance imaging
2007
Severity of childhood trauma is predictive of cocaine relapse outcomes in women but not men
Hyman SM, Paliwal P, Chaplin TM, Mazure CM, Rounsaville BJ, Sinha R. Severity of childhood trauma is predictive of cocaine relapse outcomes in women but not men. Drug And Alcohol Dependence 2007, 92: 208-216. PMID: 17900822, PMCID: PMC2233653, DOI: 10.1016/j.drugalcdep.2007.08.006.Peer-Reviewed Original ResearchMeSH KeywordsAdultAdult Survivors of Child AbuseChildChild Abuse, SexualCocaine-Related DisordersData Interpretation, StatisticalFemaleFollow-Up StudiesHumansInpatientsMaleMiddle AgedPredictive Value of TestsProspective StudiesPsychiatric Status Rating ScalesRecurrenceSex CharacteristicsSocioeconomic FactorsSubstance Abuse Treatment CentersSurveys and QuestionnairesConceptsOverall childhood traumaCocaine relapse outcomesChildhood traumaEmotional abuseRelapse outcomesChildhood emotional abuseCocaine treatment outcomesCocaine-dependent menCocaine-dependent adultsCocaine relapseAssociation of severityRisk of relapseSexual abusePhysical abuseGender-specific effectsInitial relapseDay cocaineCocaine dependenceDependent adultsInpatient SampleInpatient treatmentTreatment outcomesGreater severityAbuseDependent men
2005
A gender specific psychometric analysis of the early trauma inventory short form in cocaine dependent adults
Hyman SM, Garcia M, Kemp K, Mazure CM, Sinha R. A gender specific psychometric analysis of the early trauma inventory short form in cocaine dependent adults. Addictive Behaviors 2005, 30: 847-852. PMID: 15833587, PMCID: PMC2444015, DOI: 10.1016/j.addbeh.2004.08.009.Peer-Reviewed Original ResearchConceptsLifetime diagnosisDSM-IV Axis I DisordersMajor depressive disorderStructured Clinical InterviewAxis I DisordersCocaine-dependent adultsAlcohol use disorderCocaine-dependent menShort formChildhood Trauma Questionnaire-Short FormEarly traumaQuestionnaire-Short FormInternal consistencyClinical research toolDepressive disorderI disordersPredictive validityGood internal consistencyPsychiatric disordersUse disordersClinical InterviewDependent menCTQ-SFDependent adultsWomen