Yale Geneticist With Rare Disease to Build Pediatric Cell Atlas of Skeletal Muscle
A $3 million grant from the Chan Zuckerberg Initiative, awarded to a team of researchers led by Monkol Lek, PhD, assistant professor of genetics at Yale, will support Lek and his team in creating a Pediatric Cell Atlas of Skeletal Muscle — a roadmap of healthy skeletal cells and how they change at four key age group milestones between the ages of zero and 18 years.
Strategies to accelerate diagnosis and treatment of rare cardiovascular diseases
The current landscape for patients with rare cardiovascular disease has shifted. Using genome sequencing Yale physician-scientists have begun to elucidate the pathophysiology of genetic disorders and develop treatment guidelines and recommendations.
Parental Birth Abnormalities and Offspring’s Autism Linked
In a study of medical registry records of nearly 400,000 parent-child pairs from Denmark, a Yale School of Public Health study found that parents who themselves born very prematurely are nearly twice as likely to have children with autism spectrum disorder.
Jawless Lamprey Takes a Bite out of Oncogene Evolution
By carefully tracing the evolution of a select number of cancer-causing genes in a variety of species, the researchers evaluated which animals are — and are not — effective in gauging how an analogue of those genes in humans can lead to cancer. What they found is surprising: jawless fish such as lampreys share significant similarities in these certain genes compared to humans, while fruit flies do not.
Major Gift Will Support an Innovative Brain Research Collaboration
The Swiss-based NOMIS Foundation is making a large five-year award for research into what makes the human brain unique. The research will be a collaboration between the laboratories of James P. Noonan, PhD, associate professor of genetics and of neuroscience at Yale School of Medicine, and Franck Polleux, PhD, professor of neuroscience at Columbia University and a member of that school’s Zuckerman Institute. Their combined mission is to understand the brain and mind.